{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T21:49:37Z","timestamp":1788904177331,"version":"build-2803163510"},"reference-count":30,"publisher":"Royal College of Psychiatrists","issue":"4","license":[{"start":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T00:00:00Z","timestamp":1542931200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec id=\"S0007125018002477_sec_a1\" sec-type=\"other\"><jats:title>Background<\/jats:title><jats:p>A randomised controlled trial found that a structured mindfulness group therapy (MGT) programme was as effective as treatment as usual (mostly cognitive\u2013behavioural therapy) for patients with a diagnosis of depression, anxiety or stress and adjustment disorders in Sweden (ClinicalTrials.gov: NCT01476371).<\/jats:p><\/jats:sec><jats:sec id=\"S0007125018002477_sec_a2\" sec-type=\"other\"><jats:title>Aims<\/jats:title><jats:p>To perform a cost-effectiveness analysis of MGT compared with treatment as usual from both a healthcare and a societal perspective for the trial duration (8 weeks).<\/jats:p><\/jats:sec><jats:sec id=\"S0007125018002477_sec_a3\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>The costs from a healthcare perspective included treatment as usual, medication and costs for providing MGT. The societal perspective included costs from the healthcare perspective plus savings from productivity gains for the trial duration. The effectiveness was measured as quality-adjusted life-years (QALY) using the EQ-5D-5L questionnaire and the UK value set. Uncertainty surrounding the incremental costs and effects were estimated using non-parametric bootstrapping with 5000 replications and presented with 95% confidence intervals and cost-effectiveness acceptability curves.<\/jats:p><\/jats:sec><jats:sec id=\"S0007125018002477_sec_a4\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>The MGT group had significantly lower healthcare and societal costs (mean differences \u2013\u20ac115 (95% CI \u2212193 to \u221236) and \u2013\u20ac112 (95% CI \u2212207 to \u221217), respectively) compared with the control group. In terms of effectiveness, there was no significant difference in QALY gain (mean difference \u22120.003, 95% CI \u22120.0076 to 0.0012) between the two groups.<\/jats:p><\/jats:sec><jats:sec id=\"S0007125018002477_sec_a5\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>MGT is a cost-saving alternative to treatment as usual over the trial duration from both a healthcare and a societal perspective for patients with a diagnosis of depression, anxiety or stress and adjustment disorders in Sweden.<\/jats:p><\/jats:sec>","DOI":"10.1192\/bjp.2018.247","type":"journal-article","created":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T10:37:12Z","timestamp":1542969432000},"page":"197-203","source":"Crossref","is-referenced-by-count":20,"title":["Economic evaluation of mindfulness group therapy for patients with depression, anxiety, stress and adjustment disorders compared with treatment as usual"],"prefix":"10.1192","volume":"216","author":[{"given":"Sanjib","family":"Saha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Jarl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf-G","family":"Gerdtham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Sundquist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Sundquist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2018,11,23]]},"reference":[{"key":"S0007125018002477_ref20","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1050(199812)7:8<723::AID-HEC392>3.0.CO;2-O"},{"key":"S0007125018002477_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2011.05.002"},{"key":"S0007125018002477_ref26","volume-title":"Applied Methods of Cost-Benefit Analysis in Health Care","author":"Frew","year":"2010"},{"key":"S0007125018002477_ref21","doi-asserted-by":"publisher","DOI":"10.1002\/hec.903"},{"key":"S0007125018002477_ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-013-0422-3"},{"key":"S0007125018002477_ref18","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1050(199707)6:4<327::AID-HEC282>3.0.CO;2-W"},{"key":"S0007125018002477_ref29","doi-asserted-by":"publisher","DOI":"10.1007\/s12671-014-0282-6"},{"key":"S0007125018002477_ref12","doi-asserted-by":"publisher","DOI":"10.1002\/hec.944"},{"key":"S0007125018002477_ref14","unstructured":"Swedish Association of Local Authorities and Regions. 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