{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T05:15:33Z","timestamp":1790054133489,"version":"4.0.1"},"reference-count":42,"publisher":"Royal College of Psychiatrists","issue":"3","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec id=\"S0007125025103632_as1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Being diagnosed with cancer can be stressful and has been linked to suicide. However, an updated analyses where a wide range of cancers are compared is lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0007125025103632_as2\">\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To examine whether individuals first-time diagnosed with cancer within the past 5 years had higher suicide rates than those with no such diagnosis. Associations with time since diagnosis, and stage and site of cancer, were analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0007125025103632_as3\">\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      A population-based cohort study design applied to nationwide, longitudinal data on all persons aged 15 years or above (\n                      <jats:italic>N<\/jats:italic>\n                      = 6 987 998) and living in Denmark between 2000 and 2021. Specific sites of cancer first-time diagnosed were considered as exposure for the subsequent 5 years, and death by suicide was examined as outcome. Adjusted incidence rate ratios (aIRRRs) were calculated using Poisson regression models and adjusted for sociodemographics, psychiatric disorders and suicide attempts prior to cancer diagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0007125025103632_as4\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 707 513 (10%) individuals were included. While 12 800 individuals died by suicide in the non-cancer group, 601 died of suicide in the cancer group, resulting in an aIRR of 2.0 (95% CI: 1.9\u20132.1). The highest rate was found in the period immediately following diagnosis (&lt;6 months: 3.9, 95% CI: 3.6\u20134.2 versus 4\u20135 years: 1.8, 95% CI: 1.5\u20132.0). Also, higher rates were found for high-stage tumours (3.1, 95% CI: 2.8\u20133.4). The highest aIRRs were found for pancreatic cancer (7.5, 95% CI: 5.8\u20139.7) and oesophageal cancer (7.1, 95% CI: 5.4\u20139.3). Almost all sites of cancer analysed showed elevated rates of suicide compared with individuals without cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0007125025103632_as5\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Several recently diagnosed cancers were linked to elevated rates of suicide, especially during the first period following diagnosis. High tumour stage was associated with the highest rates, as were cancer sites with poor prognosis, suggesting prioritisation of these patient groups for suicide prevention efforts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1192\/bjp.2025.10363","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T07:00:53Z","timestamp":1756710053000},"page":"308-313","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Association between recent cancer and suicide: Danish national cohort study"],"prefix":"10.1192","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0413-1783","authenticated-orcid":false,"given":"Cecilie","family":"Fitzgerald","sequence":"first","affiliation":[{"name":"Mental Health Centre Copenhagen"},{"name":"Copenhagen Research Centre for Mental Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne Oksbjerg","family":"Dalton","sequence":"additional","affiliation":[{"name":"Danish Cancer Institute, Danish Cancer Society"},{"name":"Zealand University Hospital"},{"name":"University of Copenhagen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Frederiksen","sequence":"additional","affiliation":[{"name":"Odense University Hospital and University of Southern Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina Steinrud","family":"M\u00f8rch","sequence":"additional","affiliation":[{"name":"Danish Cancer Institute, Danish Cancer Society"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte Wessel","family":"Skovlund","sequence":"additional","affiliation":[{"name":"Danish Cancer Institute, Danish Cancer Society"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merete","family":"Nordentoft","sequence":"additional","affiliation":[{"name":"Mental Health Centre Copenhagen"},{"name":"Copenhagen Research Centre for Mental Health"},{"name":"University of Copenhagen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3475-0558","authenticated-orcid":false,"given":"Annette","family":"Erlangsen","sequence":"additional","affiliation":[{"name":"Mental Health Centre Copenhagen"},{"name":"Copenhagen Research Centre for Mental Health"},{"name":"Johns Hopkins Bloomberg School of Public Health"},{"name":"Australian National University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2025,9,1]]},"reference":[{"key":"S0007125025103632_ref4","doi-asserted-by":"publisher","DOI":"10.1002\/1099-1611(200101\/02)10:1<19::AID-PON501>3.0.CO;2-6"},{"key":"S0007125025103632_ref14","doi-asserted-by":"publisher","DOI":"10.1177\/1403494815575193"},{"key":"S0007125025103632_ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1110307"},{"key":"S0007125025103632_ref36","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2231"},{"key":"S0007125025103632_ref19","volume-title":"International Statistical Classification of Diseases and Related Health Problems: Alphabetical Index","year":"2004"},{"key":"S0007125025103632_ref18","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811399958"},{"key":"S0007125025103632_ref17","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810395825"},{"key":"S0007125025103632_ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2006.00220.x"},{"key":"S0007125025103632_ref30","unstructured":"30 Kroeftens Bekoempelse. Statistik om Kr\u00e6ft [Statistics on Cancer]. Kroeftens Bekoempelse, 2021 (https:\/\/www.cancer.dk\/nyheder\/presserum\/statistik-om-kraeft\/)."},{"key":"S0007125025103632_ref23","volume-title":"SAS System for SunOP","year":"2003"},{"key":"S0007125025103632_ref32","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.68.8358"},{"key":"S0007125025103632_ref2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920315)69:6<1509::AID-CNCR2820690632>3.0.CO;2-J"},{"key":"S0007125025103632_ref15","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810393562"},{"key":"S0007125025103632_ref24","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2400"},{"key":"S0007125025103632_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2021.08.131"},{"key":"S0007125025103632_ref16","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811401482"},{"key":"S0007125025103632_ref34","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-009120"},{"key":"S0007125025103632_ref40","doi-asserted-by":"publisher","DOI":"10.5964\/ejop.v15i3.1741"},{"key":"S0007125025103632_ref20","doi-asserted-by":"publisher","DOI":"10.2340\/1651-226X.2024.35232"},{"key":"S0007125025103632_ref29","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djaa183"},{"key":"S0007125025103632_ref11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1902944"},{"key":"S0007125025103632_ref27","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4246"},{"key":"S0007125025103632_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"S0007125025103632_ref10","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2018.3181"},{"key":"S0007125025103632_ref37","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23567"},{"key":"S0007125025103632_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.07.082"},{"key":"S0007125025103632_ref8","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602424"},{"key":"S0007125025103632_ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.genhosppsych.2019.07.003"},{"key":"S0007125025103632_ref26","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-98260-w"},{"key":"S0007125025103632_ref13","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"S0007125025103632_ref25","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5804"},{"key":"S0007125025103632_ref39","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29672"},{"key":"S0007125025103632_ref12","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"S0007125025103632_ref5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.21834"},{"key":"S0007125025103632_ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2007.05.009"},{"key":"S0007125025103632_ref28","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-022-01745-y"},{"key":"S0007125025103632_ref31","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k1415"},{"key":"S0007125025103632_ref38","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2017-0306"},{"key":"S0007125025103632_ref1","volume-title":"Oxford Textbook of Suicidology and Suicide Prevention","author":"Stenager","year":"2020"},{"key":"S0007125025103632_ref6","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-049358"},{"key":"S0007125025103632_ref33","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32146"},{"key":"S0007125025103632_ref42","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4286"}],"container-title":["The British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125025103632","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T04:20:46Z","timestamp":1788495646000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125025103632\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,1]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S0007125025103632"],"URL":"https:\/\/doi.org\/10.1192\/bjp.2025.10363","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,1]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}