{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:17:47Z","timestamp":1791346667429,"version":"4.3.1"},"reference-count":30,"publisher":"Royal College of Psychiatrists","issue":"6","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"unspecified","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec id=\"S0007125025000388_as1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sensitivity to ovarian hormone fluctuations can lead to mental distress during the luteal phase of the menstrual cycle, such as in premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD), and also during pregnancy and postpartum, as in perinatal depression (PND).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0007125025000388_as2\">\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>In two cohorts, we investigated the relationship between history of PMS\/PMDD and PND symptoms. We also examined how premenstrual symptoms are associated with perinatal symptom trajectories and dimensional phenotypes of PND symptoms, which remains unidentified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0007125025000388_as3\">\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>From early pregnancy until 6 months postpartum, participants of two large longitudinal cohorts were followed using the Edinburgh Postnatal Depression Scale (EPDS). Premenstrual symptoms were self-reported retrospectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0007125025000388_as4\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both pre-pregnancy PMS and PMDD were associated with higher EPDS scores across pregnancy and postpartum, even after adjustment for confounders. The odds of developing PND were higher among those reporting PMS and PMDD, ranging up to 1.68 (95% CI 1.25\u20132.29) (6\u201313 weeks postpartum) and 3.05 (95% CI 2.26\u20134.10) (late pregnancy) respectively for PMS and PMDD, throughout the perinatal period. Premenstrual symptomatology was associated more with certain PND trajectories based on the time of occurrence and persistence of symptoms. However, PND symptom severity did not differ depending on premenstrual symptomatology in any trajectory. Prior PMS\/PMDD was associated with underlying dimensions of symptom constructs of PND, including severe and moderate symptoms of depressed mood, anxiety and anhedonia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0007125025000388_as5\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Women with a history of PMS\/PMDD require coordinated care by psychiatrists, other mental health clinicians, midwives and gynaecologists during pregnancy as well as postpartum.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1192\/bjp.2025.38","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T04:07:09Z","timestamp":1750392429000},"page":"401-409","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":14,"title":["Trajectories and dimensional phenotypes of depressive symptoms throughout pregnancy and postpartum in relation to prior premenstrual symptoms"],"prefix":"10.1192","volume":"226","author":[{"given":"Ella","family":"Schleimann-Jensen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inger","family":"Sundstr\u00f6m-Poromaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Meltzer-Brody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tory A.","family":"Eisenlohr-Moul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fotis C.","family":"Papadopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alkistis","family":"Skalkidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2174-2068","authenticated-orcid":false,"given":"Erika","family":"Comasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2025,6,20]]},"reference":[{"key":"S0007125025000388_ref9","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2023.0069"},{"key":"S0007125025000388_ref21","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2021.222"},{"key":"S0007125025000388_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(22)00110-9"},{"key":"S0007125025000388_ref25","doi-asserted-by":"publisher","DOI":"10.3109\/08039488.2011.590606"},{"key":"S0007125025000388_ref30","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852914000480"},{"key":"S0007125025000388_ref16","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2015.5310"},{"key":"S0007125025000388_ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-023-01373-6"},{"key":"S0007125025000388_ref12","doi-asserted-by":"publisher","DOI":"10.3109\/09540269609037816"},{"key":"S0007125025000388_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(17)30136-0"},{"key":"S0007125025000388_ref1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2012.11081302"},{"key":"S0007125025000388_ref19","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S2215-0366(14)00055-8","article-title":"Heterogeneity of postpartum depression: a latent class analysis","volume":"2","author":"Putnam","year":"2015","journal-title":"Lancet Psychiatry"},{"key":"S0007125025000388_ref4","doi-asserted-by":"publisher","DOI":"10.1258\/mi.2011.011028"},{"key":"S0007125025000388_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2019.11.010"},{"key":"S0007125025000388_ref27","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m4022"},{"key":"S0007125025000388_ref15","doi-asserted-by":"publisher","DOI":"10.2217\/WHE.12.55"},{"key":"S0007125025000388_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2021.11.011"},{"key":"S0007125025000388_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2017.05.003"},{"key":"S0007125025000388_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.05.045"},{"key":"S0007125025000388_ref2","first-page":"291","article-title":"Premenstrual dysphoric disorder: burden of illness and treatment 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British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125025000388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,13]],"date-time":"2025-07-13T12:40:39Z","timestamp":1752410439000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125025000388\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0007125025000388"],"URL":"https:\/\/doi.org\/10.1192\/bjp.2025.38","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}