{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:00:20Z","timestamp":1788667220087,"version":"build-2803163510"},"reference-count":30,"publisher":"Royal College of Psychiatrists","license":[{"start":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:00:00Z","timestamp":1775433600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Br J Psychiatry"],"abstract":"<jats:sec id=\"S000712502610614X_as1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Postpartum depressive symptoms can vary substantially and probably reflect distinct subtypes. Understanding specific symptom patterns may help identify those at risk for later psychiatric care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S000712502610614X_as2\">\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>We aimed to identify subtypes of postpartum depressive symptoms and examine their associations with subsequent psychiatric care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S000712502610614X_as3\">\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We conducted a cohort study using Danish nationwide health registers linked to population-based Edinburgh Postnatal Depression Scale (EPDS) scores from 2015 to 2021. Latent class analysis of EPDS responses identified subtypes among women with clinically relevant symptoms (EPDS \u226511), using a maternal background population as a reference group (EPDS &lt;11). The outcome was psychiatric hospital contacts or redeemed psychotropic prescriptions within 1 year postpartum. We estimated standardised cumulative incidence rates and risk ratios using spline-based, time-to-event models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S000712502610614X_as4\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 162 079 women, 11 847 (7.3%) had clinically relevant symptoms (EPDS \u226511). Five subtypes were identified: Mild-depressive (23%), Moderate-anxious (17%), Moderate-depressive (18%), Moderate-overwhelmed (31%) and Severe-depressive (11%). At 1 year, the standardised cumulative incidence of psychiatric care was 69.6 (95% CI, 61.4\u201379.0) per 1000 persons in the Mild-depressive subtype. Compared with this group, the adjusted risk ratio was 0.33 (95% CI, 0.28\u20130.38) in the background maternal population, between 1.11 (95% CI, 0.93\u20131.32) and 1.25 (95% CI, 1.06\u20131.48) across moderate subtypes and 2.37 (95% CI, 1.99\u20132.82) for the Severe-depressive subtype.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S000712502610614X_as5\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Distinct subtypes of postpartum depressive symptoms were associated with varying risks of subsequent psychiatric care, depending on both symptom severity and symptom type. These findings underscore the importance of systematic screening and tailored follow-up, even for women with mild to moderate symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1192\/bjp.2026.10614","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T03:10:58Z","timestamp":1775445058000},"page":"1-8","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Subtypes of postpartum depressive symptoms and the association with subsequent psychiatric care: latent class analysis"],"prefix":"10.1192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4507-5295","authenticated-orcid":false,"given":"Sofie","family":"Egsgaard","sequence":"first","affiliation":[{"name":"University of Southern Denmark"},{"id":[{"id":"https:\/\/ror.org\/03yrrjy16","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Southern Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2736-9639","authenticated-orcid":false,"given":"Simone N.","family":"Vigod","sequence":"additional","affiliation":[{"name":"University of Toronto"},{"name":"University of Toronto"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7907-383X","authenticated-orcid":false,"given":"Lucy C.","family":"Barker","sequence":"additional","affiliation":[{"name":"University of Toronto"},{"name":"University of Toronto"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Bliddal","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03yrrjy16","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Southern Denmark"},{"name":"University of Southern Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8690-5841","authenticated-orcid":false,"given":"Hilary K.","family":"Brown","sequence":"additional","affiliation":[{"name":"University of Toronto Scarborough"},{"name":"University of Toronto"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0135-7242","authenticated-orcid":false,"given":"Cindy-Lee","family":"Dennis","sequence":"additional","affiliation":[{"name":"University of Toronto"},{"name":"Mount Sinai Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7487-3427","authenticated-orcid":false,"given":"Mette-Marie","family":"Zacher Kjeldsen","sequence":"additional","affiliation":[{"name":"Aarhus University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqin","family":"Liu","sequence":"additional","affiliation":[{"name":"Aarhus University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trine","family":"Munk-Olsen","sequence":"additional","affiliation":[{"name":"University of Southern Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2026,4,6]]},"reference":[{"key":"S000712502610614X_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-024-02038-z"},{"key":"S000712502610614X_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(17)30136-0"},{"key":"S000712502610614X_ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2018.22"},{"key":"S000712502610614X_ref2","first-page":"106","article-title":"Is postpartum depression different from depression occurring outside of the perinatal period? 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Published by Cambridge University Press on behalf of Royal College of Psychiatrists","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}