{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:30:00Z","timestamp":1790886600439,"version":"4.1.0"},"reference-count":40,"publisher":"Royal College of Psychiatrists","issue":"1","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":3654,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J\n                        Psychiatry"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Alexithymia has been shown to be related to many psychiatric and somatic\n                           illnesses. Aberrant emotion processing in the brain may underlie several\n                           psychiatric disorders. However, little is known about the neurobiological\n                           underpinnings of alexithymia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine the way in which the brain processes emotion in\n                           alexithymia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The participants were 10 healthy women with alexithymia and 11 healthy\n                           women without this condition, recruited into the study on the basis of\n                           their scores on the 20-item Toronto Alexithymia Scale. Four films were\n                           projected on a video screen to induce each of three emotional conditions\n                           (neutral, amusement, sadness). The brain areas activated during emotional\n                           stimuli in the alexithymia group were compared with those activated in\n                           the non-alexithymia group. Scans of the distribution of\n                              [<jats:sup>15<\/jats:sup>O]H<jats:sub>2<\/jats:sub>O were acquired using a positron emission\n                           tomography (PET) scanner operated in three-dimensional mode.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In response to emotional stimuli participants with alexithymia activated\n                           more parts of their sensory and motor cortices and insula, especially on\n                           the left side, and less of their anterior cingulate, compared with the\n                           control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Women with alexithymia seem to over-activate their \u2018bodily\u2019 brain\n                           regions, implying a different mode of emotion processing. This may be\n                           related to their tendency to experience physical symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1192\/bjp.bp.106.034728","type":"journal-article","created":{"date-parts":[[2008,1,3]],"date-time":"2008-01-03T21:50:38Z","timestamp":1199397038000},"page":"32-38","source":"Crossref","is-referenced-by-count":89,"title":["Cortical activation in alexithymia as a response to emotional\n                        stimuli"],"prefix":"10.1192","volume":"192","author":[{"given":"Hasse","family":"Karlsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petri","family":"N\u00e4\u00e4t\u00e4nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Stenman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S0007125000248411_ref34","doi-asserted-by":"publisher","DOI":"10.1159\/000288581"},{"key":"S0007125000248411_ref28","volume-title":"Human Brain Function","author":"Friston","year":"1997"},{"key":"S0007125000248411_ref37","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-199910000-00003"},{"key":"S0007125000248411_ref27","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.6.961"},{"key":"S0007125000248411_ref24","volume-title":"Human Brain Function","author":"Penny","year":"2003"},{"key":"S0007125000248411_ref17","first-page":"296","article-title":"A new colour atlas based on the Natural Colour System by Hering Johansson","volume":"15","author":"H\u00e5rd","year":"1966","journal-title":"Farbe"},{"key":"S0007125000248411_ref12","doi-asserted-by":"publisher","DOI":"10.1080\/02699939308409183"},{"key":"S0007125000248411_ref9","doi-asserted-by":"publisher","DOI":"10.1080\/08039480151108561"},{"key":"S0007125000248411_ref8","article-title":"The 20-item Toronto Alexithymia Scale IV. 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