{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:58:43Z","timestamp":1780534723078,"version":"3.54.1"},"reference-count":29,"publisher":"Royal College of Psychiatrists","issue":"3","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":2864,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J\n                        Psychiatry"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Age at the first psychotic episode and an interval between the onset of\n                           epilepsy and that of psychosis reflect developmental processes of\n                           interictal psychosis. However, factors relating to these indices remain\n                           unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To identify clinical variables that are associated with the timing of the\n                           development of interictal psychosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In 285 adults with epilepsy with interictal psychosis, effects of\n                           epileptic (epilepsy type), organic (intellectual functioning) and genetic\n                           (family history of psychosis) variables on timing of the development of\n                           psychosis were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean interval between the onset of epilepsy and that of psychosis was\n                           14.4 years. Some psychosis occurred within a few years of the first\n                           seizure. Generalised epilepsy, normal intellectual function and a\n                           positive family history of psychosis were associated with early onset of\n                           psychosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Early development of interictal psychosis in people with epilepsy may\n                           reflect other individual vulnerabilities to psychosis rather than\n                           epilepsy-related damage.<\/jats:p><\/jats:sec>","DOI":"10.1192\/bjp.bp.108.056721","type":"journal-article","created":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T11:30:29Z","timestamp":1267443029000},"page":"212-216","source":"Crossref","is-referenced-by-count":37,"title":["Epileptic, organic and genetic vulnerabilities for timing of the\n                        development of interictal psychosis"],"prefix":"10.1192","volume":"196","author":[{"given":"Naoto","family":"Adachi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nozomi","family":"Akanuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masumi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsunekatsu","family":"Hara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasunori","family":"Oana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Matsuura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiro","family":"Okubo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teiichi","family":"Onuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S000712500025188X_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.461004.x"},{"key":"S000712500025188X_ref23","volume-title":"Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM\u2013IV)","year":"1994"},{"key":"S000712500025188X_ref16","first-page":"593","volume-title":"Handbook of Clinical Neurology, vol.15","author":"Bruens","year":"1974"},{"key":"S000712500025188X_ref6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.9.1310"},{"key":"S000712500025188X_ref29","doi-asserted-by":"publisher","DOI":"10.1037\/h0079307"},{"key":"S000712500025188X_ref26","article-title":"IQ and risk for schizophrenia: a population-based cohort study","volume":"158","author":"David","year":"1997","journal-title":"Psychol Med"},{"key":"S000712500025188X_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291799001786"},{"key":"S000712500025188X_ref17","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.155.3.325"},{"key":"S000712500025188X_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1982.tb00307.x"},{"key":"S000712500025188X_ref18","article-title":"Tenkan to seishinbyou: rinshou-kenkyu ni okeru kadai. 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