{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:24:28Z","timestamp":1761675868444},"reference-count":15,"publisher":"Royal College of Psychiatrists","issue":"4","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":2285,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>It is hypothesised that the risk of schizophrenia may be elevated in children conceived following a short interpregnancy interval, when maternal folate stores are still being replenished. We examined the relationship between inter-pregnancy interval and schizophrenia risk in a longitudinal, population-based cohort. Risk of schizophrenia was increased by approximately 150% in those born following a pregnancy interval of $6 months, but was not increased if the interval after birth of the participant, before conception of the subsequent sibling, was $6 months. These findings support the hypothesis that folate (or other micronutrient) deficiency during fetal development may be an important risk factor for schizophrenia.<\/jats:p>","DOI":"10.1192\/bjp.bp.111.092916","type":"journal-article","created":{"date-parts":[[2011,8,5]],"date-time":"2011-08-05T00:34:53Z","timestamp":1312504493000},"page":"338-339","source":"Crossref","is-referenced-by-count":32,"title":["Pre-conception inter-pregnancy interval and risk of schizophrenia"],"prefix":"10.1192","volume":"199","author":[{"given":"Lihini","family":"Gunawardana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George Davey","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanley","family":"Zammit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elise","family":"Whitley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Gunnell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Finn","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S0007125000258388_ref15","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2010.110"},{"key":"S0007125000258388_ref13","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2371"},{"key":"S0007125000258388_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2003.10.002"},{"key":"S0007125000258388_ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8709.2007.00092.x"},{"key":"S0007125000258388_ref4","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a010236"},{"key":"S0007125000258388_ref12","volume-title":"International Classification of Diseases, Ninth Revision","year":"1977"},{"key":"S0007125000258388_ref8","doi-asserted-by":"publisher","DOI":"10.1089\/15246090050020718"},{"key":"S0007125000258388_ref14","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.65.10.1136"},{"key":"S0007125000258388_ref11","volume-title":"International Statistical Classification of Diseases and Related Health Problems, 10th Revision","year":"1992"},{"key":"S0007125000258388_ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1992.01820120071010"},{"key":"S0007125000258388_ref7","article-title":"Erythrocyte folate, plasma folate and plasma homocysteine during normal pregnancy and postpartum: a longitudinal study comprising 404 Danish women","volume":"76","author":"Milman","year":"2006","journal-title":"Eur J Haematol"},{"key":"S0007125000258388_ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.5.557"},{"key":"S0007125000258388_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)07105-7"},{"key":"S0007125000258388_ref5","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbn096"},{"key":"S0007125000258388_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbl041"}],"container-title":["British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125000258388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T04:41:11Z","timestamp":1556340071000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125000258388\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S0007125000258388"],"URL":"https:\/\/doi.org\/10.1192\/bjp.bp.111.092916","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}