{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:14:27Z","timestamp":1787166867759,"version":"build-2736575974"},"reference-count":10,"publisher":"Royal College of Psychiatrists","issue":"1","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":1097,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J\n                        Psychiatry"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>We investigated the morphology of multiple brain regions in a rare sample of\n                        15 very heavy cannabis users with minimal psychiatric comorbidity or\n                        significant exposure to other substances (compared with 15 age- and\n                        IQ-matched non-cannabis-using controls) using manual techniques. Heavy\n                        cannabis users demonstrated smaller hippocampus and amygdala volumes, but no\n                        alterations of the orbitofrontal and anterior- and paracingulate cortices,\n                        or the pituitary gland. These findings indicate that chronic cannabis use\n                        has a selective and detrimental impact on the morphology of the\n                        mediotemporal lobe.<\/jats:p>","DOI":"10.1192\/bjp.bp.114.151407","type":"journal-article","created":{"date-parts":[[2014,11,28]],"date-time":"2014-11-28T10:46:44Z","timestamp":1417171604000},"page":"77-78","source":"Crossref","is-referenced-by-count":81,"title":["Gross morphological brain changes with chronic, heavy cannabis\n                        use"],"prefix":"10.1192","volume":"206","author":[{"given":"Valentina","family":"Lorenzetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Solowij","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Whittle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Fornito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan I.","family":"Lubman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Pantelis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Y\u00fccel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S0007125000237458_ref9","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2012.39"},{"key":"S0007125000237458_ref8","doi-asserted-by":"publisher","DOI":"10.1111\/pcn.12085"},{"key":"S0007125000237458_ref6","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.185.1.5"},{"key":"S0007125000237458_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.12.033"},{"key":"S0007125000237458_ref1","doi-asserted-by":"publisher","DOI":"10.2174\/13816128113199990435"},{"key":"S0007125000237458_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.06.061"},{"key":"S0007125000237458_ref4","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.65.6.694"},{"key":"S0007125000237458_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2011.10.029"},{"key":"S0007125000237458_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(88)91597-1"},{"key":"S0007125000237458_ref10","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws136"}],"container-title":["British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125000237458","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T16:38:24Z","timestamp":1555864704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125000237458\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S0007125000237458"],"URL":"https:\/\/doi.org\/10.1192\/bjp.bp.114.151407","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1]]}}}