{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:04:26Z","timestamp":1783692266662,"version":"3.55.0"},"reference-count":47,"publisher":"Royal College of Psychiatrists","issue":"5","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":977,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Psychiatry"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Clinical and population-based studies report increased prevalence of autism spectrum disorders (ASD) in individuals with anorexia nervosa and in their relatives. No nationwide study has yet been published on co-occurrence of these disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To investigate comorbidity of ASD in individuals with anorexia nervosa, and aggregation of ASD and anorexia nervosa in their relatives.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In Danish registers we identified all individuals born in 1981\u20132008, their parents, and full and half siblings, and linked them to data on hospital admissions for psychiatric disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Risk of comorbidity of ASD in probands with anorexia nervosa and aggregation of ASD in families of anorexia nervosa probands were increased. However, the risk of comorbid and familial ASD did not differ significantly from comorbid and familial major depression or any psychiatric disorder in anorexia nervosa probands.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We confirm aggregation of ASD in probands with anorexia nervosa and in their relatives; however, the relationship between anorexia nervosa and ASD appears to be non-specific.<\/jats:p><\/jats:sec>","DOI":"10.1192\/bjp.bp.114.153221","type":"journal-article","created":{"date-parts":[[2015,2,6]],"date-time":"2015-02-06T05:41:26Z","timestamp":1423201286000},"page":"401-407","source":"Crossref","is-referenced-by-count":65,"title":["Autism spectrum disorder in individuals with anorexia nervosa and in their first- and second-degree relatives: Danish nationwide register-based cohort-study"],"prefix":"10.1192","volume":"206","author":[{"given":"Susanne V.","family":"Koch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janne T.","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svend E.","family":"Mouridsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Bentz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liselotte","family":"Petersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Bulik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preben B.","family":"Mortensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin J.","family":"Plessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S0007125000238269_ref38","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61748-7"},{"key":"S0007125000238269_ref43","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1994.tb01590.x"},{"key":"S0007125000238269_ref47","doi-asserted-by":"publisher","DOI":"10.1017\/S104161020600319X"},{"key":"S0007125000238269_ref32","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.56.5.468"},{"key":"S0007125000238269_ref46","doi-asserted-by":"publisher","DOI":"10.1186\/1745-0179-5-4"},{"key":"S0007125000238269_ref12","doi-asserted-by":"publisher","DOI":"10.1186\/2040-2392-4-44"},{"key":"S0007125000238269_ref26","doi-asserted-by":"crossref","unstructured":"Steinhausen HC , Jakobsen H , Helenius D , Munk-Jorgensen P , Strober M . A nation-wide study of the family aggregation and risk factors in anorexia nervosa over three generations. Int J Eat Disord 2014; April 28 (Epub ahead of print).","DOI":"10.1002\/eat.22293"},{"key":"S0007125000238269_ref19","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"S0007125000238269_ref33","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbt114"},{"key":"S0007125000238269_ref5","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.8.1284"},{"key":"S0007125000238269_ref4","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/315429"},{"key":"S0007125000238269_ref15","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291711002881"},{"key":"S0007125000238269_ref1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.3.469"},{"key":"S0007125000238269_ref6","article-title":"Outcome of teenage-onset anorexia nervosa in a Swedish community-based sample","volume":"12","author":"Rastam","year":"2003","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"S0007125000238269_ref20","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811401482"},{"key":"S0007125000238269_ref16","article-title":"The clinical implications of high levels of autism spectrum disorder features in anorexia nervosa: a pilot study","volume":"4","author":"Huke","year":"2014","journal-title":"Eur Eat Disord Rev"},{"key":"S0007125000238269_ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-008-0865-0"},{"key":"S0007125000238269_ref24","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn081"},{"key":"S0007125000238269_ref44","first-page":"A4578","article-title":"The validity of the schizophrenia diagnosis in the Danish Psychiatric Central Research Register is good","volume":"60","author":"Uggerby","year":"2013","journal-title":"Dan Med J"},{"key":"S0007125000238269_ref21","volume-title":"Classification of Diseases: Extended Danish-Latin Version of the World Health Organization International Classification of Diseases, 8th Revision, 1965.","year":"1971"},{"key":"S0007125000238269_ref3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-clinpsy-050212-185546"},{"key":"S0007125000238269_ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2010.08.005"},{"key":"S0007125000238269_ref2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291701003087"},{"key":"S0007125000238269_ref7","article-title":"Are autism and anorexia nervosa related?","volume":"39","author":"Gillberg","year":"1985","journal-title":"Nord J Psychiatry"},{"key":"S0007125000238269_ref9","doi-asserted-by":"publisher","DOI":"10.3109\/08039488.2012.674554"},{"key":"S0007125000238269_ref10","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.133.6.976"},{"key":"S0007125000238269_ref11","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/2040-2392-4-24","article-title":"Do girls with anorexia nervosa have elevated autistic traits?","volume":"4","author":"Baron-Cohen","year":"2013","journal-title":"Mol Autism"},{"key":"S0007125000238269_ref13","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-13-222"},{"key":"S0007125000238269_ref14","doi-asserted-by":"publisher","DOI":"10.1080\/13803390903066857"},{"key":"S0007125000238269_ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-005-0494-3"},{"key":"S0007125000238269_ref18","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810395825"},{"key":"S0007125000238269_ref22","volume-title":"The IDC-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research.","year":"1993"},{"key":"S0007125000238269_ref23","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0b013e31822bc7b7"},{"key":"S0007125000238269_ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-011-1184-2"},{"key":"S0007125000238269_ref29","doi-asserted-by":"publisher","DOI":"10.1002\/eat.10221"},{"key":"S0007125000238269_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60072-6"},{"key":"S0007125000238269_ref39","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e3181c6c7ca"},{"key":"S0007125000238269_ref31","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30149"},{"key":"S0007125000238269_ref34","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2014.00048"},{"key":"S0007125000238269_ref35","article-title":"Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis","volume":"381","author":"Smoller","year":"2013","journal-title":"Lancet"},{"key":"S0007125000238269_ref36","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60223-8"},{"key":"S0007125000238269_ref37","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2010.128"},{"key":"S0007125000238269_ref40","article-title":"What is remission in adolescent anorexia nervosa? A review of various conceptualizations and quantitative analysis","volume":"39","author":"Couturier","year":"2006","journal-title":"Int J Eat Disord"},{"key":"S0007125000238269_ref41","doi-asserted-by":"publisher","DOI":"10.1002\/eat.20261"},{"key":"S0007125000238269_ref45","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-009-0818-0"},{"key":"S0007125000238269_ref8","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2244"},{"key":"S0007125000238269_ref25","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.4081"}],"container-title":["British Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007125000238269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T18:32:30Z","timestamp":1598725950000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007125000238269\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S0007125000238269"],"URL":"https:\/\/doi.org\/10.1192\/bjp.bp.114.153221","relation":{},"ISSN":["0007-1250","1472-1465"],"issn-type":[{"value":"0007-1250","type":"print"},{"value":"1472-1465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5]]}}}