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The current treatment of choice is pharmacological or behavioural, addressing tics or the premonitory urges preceding tic onset.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The current study reports an open trial evaluating the effectiveness of a cognitive psychophysiological treatment addressing Tourette-specific sensorimotor activation processes rather than the tic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Forty-nine people with Tourette syndrome and 36 people with chronic tics completed 10 weeks of individual cognitive psychophysiological therapy. Outcome measures included two tic severity scales and psychosocial measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Post-treatment both groups had significantly improved on the tic scales with strong effect sizes across tic locations and complex and simple tics, maintained at 6-month follow-up with further change in perfectionism and self-esteem.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The cognitive psychophysiological approach targeting underlying sensorimotor processes rather than tics in Tourette's and chronic tic disorder reduced symptoms with a large effect size.<\/jats:p><\/jats:sec>","DOI":"10.1192\/bjp.bp.114.154518","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T00:39:27Z","timestamp":1438907967000},"page":"76-83","source":"Crossref","is-referenced-by-count":49,"title":["Evaluation of a cognitive psychophysiological model for management of tic disorders: an open trial"],"prefix":"10.1192","volume":"209","author":[{"given":"Kieron","family":"O'Connor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Lavoie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Blanchet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-\u00c8ve","family":"St-Pierre-Delorme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"170","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"S0007125000244401_ref46","volume-title":"Echolalia: A Novel.","author":"Seligman","year":"1991"},{"key":"S0007125000244401_ref45","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.2010.22.3.348"},{"key":"S0007125000244401_ref44","doi-asserted-by":"publisher","DOI":"10.1176\/appi.neuropsych.10010013"},{"key":"S0007125000244401_ref43","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145702002900"},{"key":"S0007125000244401_ref40","doi-asserted-by":"publisher","DOI":"10.1037\/h0081176"},{"key":"S0007125000244401_ref39","doi-asserted-by":"publisher","DOI":"10.1177\/001316447903900413"},{"key":"S0007125000244401_ref36","doi-asserted-by":"publisher","DOI":"10.1016\/0005-7967(88)90116-7"},{"key":"S0007125000244401_ref34","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4679(199511)51:6<768::AID-JCLP2270510607>3.0.CO;2-1"},{"key":"S0007125000244401_ref28","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.56.6.893"},{"key":"S0007125000244401_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2009.07.021"},{"key":"S0007125000244401_ref25","volume-title":"Personality Questionnaire (PDQ-4).","author":"Hyler","year":"1994"},{"key":"S0007125000244401_ref23","volume-title":"Questionnaire OC-TS modifi\u00e9. 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