{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T04:23:48Z","timestamp":1793075028063,"version":"4.5.0"},"reference-count":32,"publisher":"Royal College of Psychiatrists","issue":"2","license":[{"start":{"date-parts":[[2018,1,2]],"date-time":"2018-01-02T00:00:00Z","timestamp":1514851200000},"content-version":"unspecified","delay-in-days":672,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BJPsych open"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Internet cognitive\u2013behavioural therapy (iCBT) for panic disorder of up to 10 lessons is well established. The utility of briefer programmes is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine the efficacy and effectiveness of a five-lesson iCBT programme for panic disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Study 1 (efficacy): Randomised controlled trial comparing active iCBT (<jats:italic>n<\/jats:italic>=27) and waiting list control participants (<jats:italic>n<\/jats:italic>=36) on measures of panic severity and comorbid symptoms. Study 2 (effectiveness): 330 primary care patients completed the iCBT programme under the supervision of primary care practitioners.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>iCBT was significantly more effective than waiting list control in reducing panic (<jats:italic>g<\/jats:italic>=0.97, 95% CI 0.34 to 1.61), distress (<jats:italic>g<\/jats:italic>=0.92, 95% CI 0.28 to 1.55), disability (<jats:italic>g<\/jats:italic>=0.81, 95% CI 0.19 to 1.44) and depression (<jats:italic>g<\/jats:italic>=0.79, 95% CI 0.17 to 1.41), and gains were maintained at 3 months post-treatment (iCBT group). iCBT remained effective in primary care, but lower completion rates were found (56.1% in study 2 v. 63% in study 1). Adherence appeared to be related to therapist contact.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The five-lesson Panic Program has utility for treating panic disorder, which translates to primary care. 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