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However, it remains unclear which factors might predict improvement in personality functioning.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0924933824017802_sec2\" sec-type=\"methods\">\n\t    <jats:title>Methods<\/jats:title>\n\t    <jats:p>We examined a sample of 648 completed psychodynamic psychotherapies conducted by 172 therapists at the Heidelberg Institute for Psychotherapy. A machine learning approach was used to filter for variables that are relevant for the prediction of the improvement of personality functioning from a broad data set of variables collected at the beginning of each psychodynamic psychotherapy.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0924933824017802_sec3\" sec-type=\"results\">\n\t    <jats:title>Results<\/jats:title>\n\t    <jats:p>On average, we found an improvement of 0.24 (SD = 0.48) in the OPD-SQ. This corresponds to a medium effect in the improvement of personality functioning. Patients with initially high impairment experienced particularly large improvements. Overall, we found a large number of variables that proved to be predictive for the improvement of personality functioning. Limitations in social activity due to physical and emotional problems proved to be one of the most important predictors of improvement. Most of the effect sizes were small.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S0924933824017802_sec4\" sec-type=\"conclusions\">\n\t    <jats:title>Conclusions<\/jats:title>\n\t    <jats:p>Overall, the improvement in personality functioning during psychotherapy is determined more by the sum of a large number of small effects than by individual variables. 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