{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:45:22Z","timestamp":1787021122293,"version":"build-2736575974"},"reference-count":81,"publisher":"Royal College of Psychiatrists","issue":"1","license":[{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"unspecified","delay-in-days":169,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur. Psychiatr."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0924933825100400_sec1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Childhood maltreatment (CM) is a risk factor for mental and physical health problems in adulthood, potentially mediated by long-term autonomic nervous system (ANS) dysregulation. To explore this link, the association between CM and vagal-sensitive heart rate variability (HRV) metrics in adults was examined, accounting for biopsychosocial factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933825100400_sec2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from 4,420 participants in the Study of Health in Pomerania were analyzed, with CM assessed using the Childhood Trauma Questionnaire. HRV was derived from 10-second electrocardiograms and 5-minute pre-sleep polysomnographic recordings. Post hoc analyses examined abuse and neglect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933825100400_sec3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      CM was associated with reduced HRV (logRMSSD:\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.20 [95%-CI: \u22120.28, \u22120.12],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a01.2e\u221206), driven by neglect (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.27 [\u22120.35, \u22120.18],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a01.9e\u221209) rather than abuse (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a00.01 [\u22120.12, 0.14],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a01). Adjustments for age, sex, and medication attenuated these effects, which remained robust after additionally controlling for socioeconomic, lifestyle, body mass index, and depressive symptoms (fully adjusted model: CM\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.08 [\u22120.15, \u22120.001],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.047; neglect\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.11 [\u22120.19, \u22120.03],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.009; abuse\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.08 [\u22120.20, \u22120.04],\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.174). Age-related differences were found, with reduced HRV in both young and older participants but not in middle-aged participants (fully adjusted:\n                      <jats:italic>F<\/jats:italic>\n                      (2,743)\u00a0=\u00a06.75,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933825100400_sec4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study highlights long-term ANS dysregulation following CM, particularly neglect, indicated by altered vagal-sensitive HRV metrics. Although small in magnitude, the effect on the ANS was independent of adult biopsychosocial factors. This long-term dysregulation may contribute to an increased risk of adverse health outcomes in adulthood.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1192\/j.eurpsy.2025.10040","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T01:59:38Z","timestamp":1750298378000},"source":"Crossref","is-referenced-by-count":6,"title":["Long-term alteration of heart rate variability following childhood maltreatment: Results of a general population study"],"prefix":"10.1192","volume":"68","author":[{"given":"Marian","family":"St\u00fcrmer","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/025vngs54","id-type":"ROR","asserted-by":"publisher"}],"name":"University Medicine 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