{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:45:11Z","timestamp":1791499511680,"version":"4.3.4"},"reference-count":0,"publisher":"Royal College of Psychiatrists","issue":"1","license":[{"start":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T00:00:00Z","timestamp":1761264000000},"content-version":"unspecified","delay-in-days":296,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur. Psychiatr."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0924933825101028_sec1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Among the clinical features of bipolar disorder (BD), sleep disturbances are highly prevalent and persist across all phases of the illness, from onset to acute and inter-episodic periods. Substantial evidence suggests that sleep disturbances may function as proximal triggers for suicidal behavior, independent of other underlying psychiatric conditions. Although suicide is a major clinical concern in BD, the interplay between sleep disturbances and suicidality remains incompletely understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933825101028_sec2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a systematic review and meta-analysis (SRMA) following the PRISMA guidelines. We performed a comprehensive search across PubMed, PsycINFO, and SCOPUS, including all studies reporting an association between sleep disturbances and suicidal behavior in BD. A total of 16 reports, comprising 14 cross-sectional studies and two longitudinal studies, were included in this SRMA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933825101028_sec3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among individuals with BD, sleep disturbances were associated with increased odds of lifetime suicidal behaviors (OR\u00a0=\u00a01.51, 95% CI\u00a0=\u00a01.23, 1.86), and a history of suicide attempts was associated with significantly elevated odds of experiencing sleep disturbances (OR\u00a0=\u00a01.37, 95% CI\u00a0=\u00a01.21, 1.55). In addition, poor sleep quality as measured by the Pittsburgh Sleep Quality Index positively correlated with suicidality (r\u00a0=\u00a00.24, 95% CI\u00a0=\u00a00.10, 0.36).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933825101028_sec4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These results highlight the link between sleep disturbances and suicidal tendencies in individuals with BD. Prompt recognition and treatment of sleep disturbances could be crucial for averting or reducing suicidal behaviors in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1192\/j.eurpsy.2025.10102","type":"journal-article","created":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T06:25:58Z","timestamp":1761287158000},"source":"Crossref","is-referenced-by-count":2,"title":["Boulevard of broken rhythms: A systematic review and meta-analysis on the relationship between sleep disturbances and suicidal behavior in bipolar disorder"],"prefix":"10.1192","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7217-5319","authenticated-orcid":false,"given":"Marta","family":"Bort","sequence":"first","affiliation":[{"name":"Universitat de Barcelona (UB)"},{"name":"Hospital Cl\u00ednic de Barcelona"},{"id":[{"id":"https:\/\/ror.org\/054vayn55","id-type":"ROR","asserted-by":"publisher"}],"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS)"},{"name":"Instituto de Salud Carlos III"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6187-0187","authenticated-orcid":false,"given":"Chiara","family":"Possidente","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01111rn36","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Bologna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5961-6032","authenticated-orcid":false,"given":"Vincenzo","family":"Oliva","sequence":"additional","affiliation":[{"name":"Universitat de Barcelona (UB)"},{"name":"Hospital Cl\u00ednic de Barcelona"},{"id":[{"id":"https:\/\/ror.org\/054vayn55","id-type":"ROR","asserted-by":"publisher"}],"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS)"},{"name":"Instituto de Salud Carlos III"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2032-1181","authenticated-orcid":false,"given":"Michele","family":"De Prisco","sequence":"additional","affiliation":[{"name":"Universitat de Barcelona (UB)"},{"name":"Hospital Cl\u00ednic de Barcelona"},{"id":[{"id":"https:\/\/ror.org\/054vayn55","id-type":"ROR","asserted-by":"publisher"}],"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS)"},{"name":"Instituto de Salud Carlos III"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3985-5101","authenticated-orcid":false,"given":"Constanza","family":"Sommerhoff","sequence":"additional","affiliation":[{"name":"Universitat de Barcelona (UB)"},{"name":"Hospital Cl\u00ednic de Barcelona"},{"id":[{"id":"https:\/\/ror.org\/054vayn55","id-type":"ROR","asserted-by":"publisher"}],"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer 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(IDIBAPS)"},{"name":"Instituto de Salud Carlos III"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6320-4420","authenticated-orcid":false,"given":"Andrea","family":"Murru","sequence":"additional","affiliation":[{"name":"Universitat de Barcelona (UB)"},{"name":"Hospital Cl\u00ednic de Barcelona"},{"id":[{"id":"https:\/\/ror.org\/054vayn55","id-type":"ROR","asserted-by":"publisher"}],"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS)"},{"name":"Instituto de Salud Carlos III"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"170","published-online":{"date-parts":[[2025,10,24]]},"container-title":["European Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0924933825101028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:01:49Z","timestamp":1762862509000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0924933825101028\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025]]}},"alternative-id":["S0924933825101028"],"URL":"https:\/\/doi.org\/10.1192\/j.eurpsy.2025.10102","relation":{},"ISSN":["0924-9338","1778-3585"],"issn-type":[{"value":"0924-9338","type":"print"},{"value":"1778-3585","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"e154"}}