{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T01:03:20Z","timestamp":1794013400760,"version":"4.8.0"},"reference-count":87,"publisher":"Royal College of Psychiatrists","issue":"1","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"unspecified","delay-in-days":84,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"tdm","delay-in-days":84,"URL":"https:\/\/www.cambridge.org\/tdm\/tdmrep-policy.json"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur. 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This work aims to develop French recommendations based on experts\u2019 consensus on the use of antidepressants in unipolar late-life depression, to guide safer prescribing practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933826122068_sec2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This tool was developed using a Delphi survey, based on a review of literature published between 2014 and 2024 and focused on \u201cantidepressants\u201d and \u201clate-life depression\u201d Experts from various fields: geriatric psychiatry, clinical pharmacy and general practice, rated items using a 9-point Likert scale. Items with a median score\u00a0\u2265\u00a07 and at least 80% agreement were validated and included in the final version of the tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933826122068_sec3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty to 23 experts per round, different from the authors of the proposed items, participated in a four-round Delphi process. The resulting tool includes 57 validated items across 10 sections and a stepped-care algorithm for treating major depression in older adults. It addresses drug choice, dosing, monitoring, comorbidities, and treatment resistance, prioritizing safe first-line options like sertraline, citalopram, and escitalopram.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0924933826122068_sec4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A Delphi survey involving multidisciplinary experts led to a French consensus tool for prescribing antidepressants in unipolar late-life depression. It integrates clinical evidence and expert judgment to address treatment complexity, drug safety, and resistance. The tool offers practical, stepwise recommendations tailored to primary care, aiming to optimize antidepressant use, reduce iatrogenesis, and improve patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1192\/j.eurpsy.2026.12206","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T08:51:55Z","timestamp":1774515115000},"source":"Crossref","is-referenced-by-count":2,"title":["Optimizing antidepressant use in geriatric depression: expert consensus from French societies of geriatrics, old age psychiatry, and clinical pharmacy (SFGG, SF3PA, and SFPC)"],"prefix":"10.1192","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4162-9441","authenticated-orcid":false,"given":"Morgane","family":"Houix","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05c1qsg97","id-type":"ROR","asserted-by":"publisher"}],"name":"CHU Nantes: Centre Hospitalier Universitaire de Nantes"},{"name":"INSERM UMR 1246 SPHERE Methods in 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