{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:58:18Z","timestamp":1787065098338,"version":"build-2736575974"},"reference-count":69,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T00:00:00Z","timestamp":1599782400000},"content-version":"vor","delay-in-days":1198,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK054927"],"award-info":[{"award-number":["DK054927"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL057244"],"award-info":[{"award-number":["HL057244"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL075316"],"award-info":[{"award-number":["HL075316"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jlr.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Lipid Research"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1194\/jlr.m072587","type":"journal-article","created":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T20:25:28Z","timestamp":1492028728000},"page":"1080-1090","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"title":["NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury"],"prefix":"10.1016","volume":"58","author":[{"given":"Guangbi","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhida","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owais M.","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine M.","family":"Abais-Battad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabena M.","family":"Conley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph K.","family":"Ritter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pin-Lan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1194\/jlr.M072587_bib1","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1007\/s00726-012-1321-z","article-title":"Paraoxonase 1 and homocysteine metabolism","volume":"43","author":"Per\u0142a-Kaj\u00e1n","year":"2012","journal-title":"Amino Acids."},{"key":"10.1194\/jlr.M072587_bib2","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1097\/FPC.0b013e32835693f7","article-title":"Association of COMT, MTHFR, and SLC19A1(RFC-1) polymorphisms with homocysteine blood levels and cognitive impairment in Parkinson's disease","volume":"22","author":"Bia\u0142ecka","year":"2012","journal-title":"Pharmacogenet. Genomics."},{"key":"10.1194\/jlr.M072587_bib3","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.exer.2011.12.011","article-title":"Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia","volume":"96","author":"Yu","year":"2012","journal-title":"Exp. Eye Res."},{"key":"10.1194\/jlr.M072587_bib4","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/j.clinbiochem.2012.05.031","article-title":"Role of homocysteine in end-stage renal disease","volume":"45","author":"Wu","year":"2012","journal-title":"Clin. Biochem."},{"key":"10.1194\/jlr.M072587_bib5","doi-asserted-by":"crossref","first-page":"27159","DOI":"10.1074\/jbc.M114.567537","article-title":"Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia","volume":"289","author":"Abais","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.M072587_bib6","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.freeradbiomed.2013.10.009","article-title":"Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia","volume":"67","author":"Abais","year":"2014","journal-title":"Free Radic. Biol. Med."},{"key":"10.1194\/jlr.M072587_bib7","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1089\/ars.2012.4666","article-title":"NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia","volume":"18","author":"Abais","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1194\/jlr.M072587_bib8","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1161\/HYPERTENSIONAHA.111.189688","article-title":"Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia","volume":"60","author":"Zhang","year":"2012","journal-title":"Hypertension."},{"key":"10.1194\/jlr.M072587_bib9","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.freeradbiomed.2010.01.029","article-title":"Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene","volume":"48","author":"Zhang","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1194\/jlr.M072587_bib10","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1161\/01.ATV.0000035404.18281.37","article-title":"Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: role of chemokine and adhesion molecules","volume":"22","author":"Wang","year":"2002","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1194\/jlr.M072587_bib11","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1089\/ars.2014.6125","article-title":"Hierarchical regulation of wound healing by NOD-like receptors in cardiovascular disease","volume":"22","author":"Bracey","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1194\/jlr.M072587_bib12","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1089\/ars.2015.6319","article-title":"Cardiovascular pathobiology of inflammasomes: inflammatory machinery and beyond","volume":"22","author":"Li","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1194\/jlr.M072587_bib13","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.bbi.2012.05.011","article-title":"Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial","volume":"26","author":"Kiecolt-Glaser","year":"2012","journal-title":"Brain Behav. Immun."},{"key":"10.1194\/jlr.M072587_bib14","doi-asserted-by":"crossref","first-page":"43079","DOI":"10.1074\/jbc.M509796200","article-title":"The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering","volume":"280","author":"Ariel","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.M072587_bib15","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1161\/CIRCULATIONAHA.116.021894","article-title":"Resolvin D2 enhances postischemic revascularization while resolving inflammation","volume":"134","author":"Zhang","year":"2016","journal-title":"Circulation."},{"key":"10.1194\/jlr.M072587_bib16","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.bbi.2015.12.013","article-title":"Resolvin D1 and E1 promote resolution of inflammation in microglial cells in vitro","volume":"55","author":"Rey","year":"2016","journal-title":"Brain Behav. Immun."},{"key":"10.1194\/jlr.M072587_bib17","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.ajpath.2015.12.012","article-title":"The protectin PCTR1 is produced by human M2 macrophages and enhances resolution of infectious inflammation","volume":"186","author":"Ramon","year":"2016","journal-title":"Am. J. Pathol."},{"key":"10.1194\/jlr.M072587_bib18","doi-asserted-by":"crossref","first-page":"810","DOI":"10.3760\/cma.j.issn.0366-6999.20131104","article-title":"Protectin D1 promotes resolution of inflammation in a murine model of lipopolysaccharide-induced acute lung injury via enhancing neutrophil apoptosis","volume":"127","author":"Li","year":"2014","journal-title":"Chin. Med. J. (Engl.)."},{"key":"10.1194\/jlr.M072587_bib19","doi-asserted-by":"crossref","first-page":"3480","DOI":"10.1039\/C6FO00477F","article-title":"Dietary fatty acid composition is sensed by the NLRP3 inflammasome: omega-3 fatty acid (DHA) prevents NLRP3 activation in human macrophages","volume":"7","author":"Mart\u00ednez-Micaelo","year":"2016","journal-title":"Food Funct."},{"key":"10.1194\/jlr.M072587_bib20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jnutbio.2016.01.010","article-title":"Docosahexaenoic acid and palmitic acid reciprocally modulate monocyte activation in part through endoplasmic reticulum stress","volume":"32","author":"Snodgrass","year":"2016","journal-title":"J. Nutr. Biochem."},{"key":"10.1194\/jlr.M072587_bib21","doi-asserted-by":"crossref","first-page":"3791","DOI":"10.1007\/s13277-013-0963-0","article-title":"Anti-cancer activity of DHA on gastric cancer\u2013an in vitro and in vivo study","volume":"34","author":"Sun","year":"2013","journal-title":"Tumour Biol."},{"key":"10.1194\/jlr.M072587_bib22","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1476-9255-11-6","article-title":"Anti-inflammatory effects of resolvin-D1 on human corneal epithelial cells: in vitro study","volume":"11","author":"Erdinest","year":"2014","journal-title":"J. Inflamm. (Lond.)."},{"key":"10.1194\/jlr.M072587_bib23","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1124\/jpet.110.176461","article-title":"Docosahexanoic acid-induced coronary arterial dilation: actions of 17S-hydroxy docosahexanoic acid on K+ channel activity","volume":"336","author":"Li","year":"2011","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1194\/jlr.M072587_bib24","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1016\/j.ajpath.2011.07.019","article-title":"Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in mice","volume":"179","author":"Boini","year":"2011","journal-title":"Am. J. Pathol."},{"key":"10.1194\/jlr.M072587_bib25","doi-asserted-by":"crossref","first-page":"G1150","DOI":"10.1152\/ajpgi.90455.2008","article-title":"The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway","volume":"295","author":"DeMorrow","year":"2008","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1194\/jlr.M072587_bib26","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1021\/jm00108a039","article-title":"Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase","volume":"34","author":"Cho","year":"1991","journal-title":"J. Med. Chem."},{"key":"10.1194\/jlr.M072587_bib27","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1681\/ASN.V361260","article-title":"Measurement of albumin reflection coefficient with isolated rat glomeruli","volume":"3","author":"Savin","year":"1992","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1194\/jlr.M072587_bib28","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/ki.1981.121","article-title":"Filtration in single isolated mammalian glomeruli","volume":"20","author":"Savin","year":"1981","journal-title":"Kidney Int."},{"key":"10.1194\/jlr.M072587_bib29","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1159\/000363046","article-title":"Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion","volume":"34","author":"Xia","year":"2014","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1194\/jlr.M072587_bib30","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/ki.1984.147","article-title":"Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats","volume":"26","author":"Raij","year":"1984","journal-title":"Kidney Int."},{"key":"10.1194\/jlr.M072587_bib31","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/ki.1993.320","article-title":"n-3 fatty acids reduce proteinuria in patients with chronic glomerular disease","volume":"44","author":"De Caterina","year":"1993","journal-title":"Kidney Int."},{"key":"10.1194\/jlr.M072587_bib32","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.jnutbio.2003.08.009","article-title":"Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil","volume":"14","author":"Moon","year":"2003","journal-title":"J. Nutr. Biochem."},{"key":"10.1194\/jlr.M072587_bib33","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.semnephrol.2004.01.004","article-title":"The role of fish oil\/omega-3 fatty acids in the treatment of IgA nephropathy","volume":"24","author":"Donadio","year":"2004","journal-title":"Semin. Nephrol."},{"key":"10.1194\/jlr.M072587_bib34","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1747-1028-4-6","article-title":"Chemopreventive and renal protective effects for docosahexaenoic acid (DHA): implications of CRP and lipid peroxides","volume":"4","author":"El-Mesery","year":"2009","journal-title":"Cell Div."},{"key":"10.1194\/jlr.M072587_bib35","doi-asserted-by":"crossref","first-page":"5280","DOI":"10.4049\/jimmunol.0903282","article-title":"Docosahexaenoic acid-enriched fish oil attenuates kidney disease and prolongs median and maximal life span of autoimmune lupus-prone mice","volume":"184","author":"Halade","year":"2010","journal-title":"J. Immunol."},{"key":"10.1194\/jlr.M072587_bib36","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1159\/000333479","article-title":"Effects of tridocosahexaenoyl-glycerol emulsion on proteinuria in rats with nephrotoxic serum nephritis","volume":"1","author":"Nakamura","year":"2011","journal-title":"Nephron Extra."},{"key":"10.1194\/jlr.M072587_bib37","doi-asserted-by":"crossref","first-page":"652","DOI":"10.5301\/jn.5000193","article-title":"Further insights about the beneficial effects of n-3 fatty acids in the early molecular events of renal fibrosis in vitro","volume":"26","author":"Priante","year":"2013","journal-title":"J. Nephrol."},{"key":"10.1194\/jlr.M072587_bib38","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1177\/0884533609335376","article-title":"Fish oil supplementation lowers C-reactive protein levels independent of triglyceride reduction in patients with end-stage renal disease","volume":"24","author":"Bowden","year":"2009","journal-title":"Nutr. Clin. Pract."},{"key":"10.1194\/jlr.M072587_bib39","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1046\/j.1523-1755.2000.00930.x","article-title":"Suppressive effects of fish oil on mesangial cell proliferation in vitro and in vivo","volume":"57","author":"Grande","year":"2000","journal-title":"Kidney Int."},{"key":"10.1194\/jlr.M072587_bib40","doi-asserted-by":"crossref","first-page":"3343","DOI":"10.1093\/jn\/134.12.3343","article-title":"Docosahexaenoic acid attenuates mycotoxin-induced immunoglobulin a nephropathy, interleukin-6 transcription, and mitogen-activated protein kinase phosphorylation in mice","volume":"134","author":"Jia","year":"2004","journal-title":"J. Nutr."},{"key":"10.1194\/jlr.M072587_bib41","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1089\/jmf.2006.092","article-title":"Antioxidative and anti-inflammatory actions of docosahexaenoic acid and eicosapentaenoic acid in renal epithelial cells and macrophages","volume":"10","author":"Kim","year":"2007","journal-title":"J. Med. Food."},{"key":"10.1194\/jlr.M072587_bib42","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1002\/oby.20638","article-title":"Lower NLRP3 inflammasome activity in NAG-1 transgenic mice is linked to a resistance to obesity and increased insulin sensitivity","volume":"22","author":"Wang","year":"2014","journal-title":"Obesity (Silver Spring)."},{"key":"10.1194\/jlr.M072587_bib43","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.cardfail.2015.04.014","article-title":"The importance of NLRP3 inflammasome in heart failure","volume":"21","author":"Butts","year":"2015","journal-title":"J. Card. Fail."},{"key":"10.1194\/jlr.M072587_bib44","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s13024-016-0088-1","article-title":"The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease","volume":"11","author":"Saresella","year":"2016","journal-title":"Mol. Neurodegener."},{"key":"10.1194\/jlr.M072587_bib45","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1002\/hep.26592","article-title":"NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice","volume":"59","author":"Wree","year":"2014","journal-title":"Hepatology."},{"key":"10.1194\/jlr.M072587_bib46","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.bbamcr.2014.11.012","article-title":"Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis","volume":"1853","author":"Chen","year":"2015","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.M072587_bib47","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.1161\/CIRCRESAHA.116.308362","article-title":"Ogg1-dependent DNA repair regulates NLRP3 inflammasome and prevents atherosclerosis","volume":"119","author":"Tumurkhuu","year":"2016","journal-title":"Circ. Res."},{"key":"10.1194\/jlr.M072587_bib48","doi-asserted-by":"crossref","first-page":"194","DOI":"10.2337\/db12-0420","article-title":"Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes","volume":"62","author":"Lee","year":"2013","journal-title":"Diabetes."},{"key":"10.1194\/jlr.M072587_bib49","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12989-014-0058-0","article-title":"Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs","volume":"11","author":"Peeters","year":"2014","journal-title":"Part. Fibre Toxicol."},{"key":"10.1194\/jlr.M072587_bib50","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1177\/1535370213489485","article-title":"Concentrated fish oil (Lovaza(R)) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW)F1 mice","volume":"238","author":"Halade","year":"2013","journal-title":"Exp. Biol. Med. (Maywood)."},{"key":"10.1194\/jlr.M072587_bib51","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.bbalip.2010.08.002","article-title":"Specialized pro-resolving lipid mediators in the inflammatory response: an update","volume":"1801","author":"Bannenberg","year":"2010","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.M072587_bib52","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1146\/annurev.pathmechdis.3.121806.151409","article-title":"Anti-inflammatory and proresolving lipid mediators","volume":"3","author":"Serhan","year":"2008","journal-title":"Annu. Rev. Pathol."},{"key":"10.1194\/jlr.M072587_bib53","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nri2294","article-title":"Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators","volume":"8","author":"Serhan","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"10.1194\/jlr.M072587_bib54","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.coph.2013.05.012","article-title":"Resolution phase lipid mediators of inflammation: agonists of resolution","volume":"13","author":"Serhan","year":"2013","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1194\/jlr.M072587_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biochi.2013.11.006","article-title":"Confusion between protectin D1 (PD1) and its isomer protectin DX (PDX). An overview on the dihydroxy-docosatrienes described to date","volume":"99","author":"Balas","year":"2014","journal-title":"Biochimie."},{"key":"10.1194\/jlr.M072587_bib56","doi-asserted-by":"crossref","first-page":"5902","DOI":"10.4049\/jimmunol.177.9.5902","article-title":"Resolvin D series and protectin D1 mitigate acute kidney injury","volume":"177","author":"Duffield","year":"2006","journal-title":"J. Immunol."},{"key":"10.1194\/jlr.M072587_bib57","doi-asserted-by":"crossref","first-page":"19031","DOI":"10.18632\/oncotarget.8023","article-title":"Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene","volume":"7","author":"Boini","year":"2016","journal-title":"Oncotarget."},{"key":"10.1194\/jlr.M072587_bib58","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1124\/jpet.116.233239","article-title":"Protective action of anandamide and its COX-2 metabolite against l-homocysteine-induced NLRP3 inflammasome activation and injury in podocytes","volume":"358","author":"Li","year":"2016","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1194\/jlr.M072587_bib59","doi-asserted-by":"crossref","first-page":"504761","DOI":"10.1155\/2015\/504761","article-title":"NADPH oxidase-induced NALP3 inflammasome activation is driven by thioredoxin-interacting protein which contributes to podocyte injury in hyperglycemia","volume":"2015","author":"Gao","year":"2015","journal-title":"J. Diabetes Res."},{"key":"10.1194\/jlr.M072587_bib60","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.febslet.2006.12.051","article-title":"Transcriptional suppression of nephrin in podocytes by macrophages: roles of inflammatory cytokines and involvement of the PI3K\/Akt pathway","volume":"581","author":"Takano","year":"2007","journal-title":"FEBS Lett."},{"key":"10.1194\/jlr.M072587_bib61","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/labinvest.2011.61","article-title":"c-fms blockade reverses glomerular macrophage infiltration and halts development of crescentic anti-GBM glomerulonephritis in the rat","volume":"91","author":"Han","year":"2011","journal-title":"Lab. Invest."},{"key":"10.1194\/jlr.M072587_bib62","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1054\/bjoc.2000.1481","article-title":"Increased uracil misincorporation in lymphocytes from folate-deficient rats","volume":"83","author":"Duthie","year":"2000","journal-title":"Br. J. Cancer."},{"key":"10.1194\/jlr.M072587_bib63","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1042\/bj2980415","article-title":"Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism","volume":"298","author":"Miller","year":"1994","journal-title":"Biochem. J."},{"key":"10.1194\/jlr.M072587_bib64","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1159\/000074673","article-title":"Chronic methionine load-induced hyperhomocysteinemia enhances rat carotid responsiveness for angiotensin II","volume":"70","author":"Bonaventura","year":"2004","journal-title":"Pharmacology."},{"key":"10.1194\/jlr.M072587_bib65","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.bbalip.2013.10.006","article-title":"Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis","volume":"1841","author":"Lee","year":"2014","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.M072587_bib66","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/mnfr.201400687","article-title":"Docosahexaenoic acid and eicosapentaenoic acid suppress adhesion molecule expression in human aortic endothelial cells via differential mechanisms","volume":"59","author":"Huang","year":"2015","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1194\/jlr.M072587_bib67","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/s00011-016-0971-9","article-title":"N-3 vs. n-6 fatty acids differentially influence calcium signalling and adhesion of inflammatory activated monocytes: impact of lipid rafts","volume":"65","author":"Schaefer","year":"2016","journal-title":"Inflamm. Res."},{"key":"10.1194\/jlr.M072587_bib68","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1743-7075-9-34","article-title":"Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells","volume":"9","author":"Luo","year":"2012","journal-title":"Nutr. Metab. (Lond.)."},{"key":"10.1194\/jlr.M072587_bib69","doi-asserted-by":"crossref","first-page":"e97957","DOI":"10.1371\/journal.pone.0097957","article-title":"Omega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-kappaB activation and enhancing autophagy","volume":"9","author":"Williams-Bey","year":"2014","journal-title":"PLoS One."}],"container-title":["Journal of Lipid Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022227520310014?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022227520310014?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1194\/jlr.M072587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,23]],"date-time":"2024-06-23T11:16:18Z","timestamp":1719141378000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022227520310014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":69,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0022227520310014"],"URL":"https:\/\/doi.org\/10.1194\/jlr.m072587","relation":{},"ISSN":["0022-2275"],"issn-type":[{"value":"0022-2275","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury","name":"articletitle","label":"Article Title"},{"value":"Journal of Lipid Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1194\/jlr.M072587","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}