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Dev."},{"key":"10.1194\/jlr.M800538-JLR200_bib70","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1194\/jlr.M700554-JLR200","article-title":"Cholesterol supply and SREBPs modulate transcription of the Niemann-Pick C-1 gene in steroidogenic tissues","volume":"49","author":"G\u00e8vry","year":"2008","journal-title":"J. Lipid Res."},{"key":"10.1194\/jlr.M800538-JLR200_bib71","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.cmet.2008.04.001","article-title":"The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1","volume":"7","author":"Ge","year":"2008","journal-title":"Cell Metab."},{"key":"10.1194\/jlr.M800538-JLR200_bib72","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0022-2275(20)39694-2","article-title":"Regulation of sterol carrier protein-2 gene expression in rat liver and small intestine","volume":"34","author":"Baum","year":"1993","journal-title":"J. Lipid Res."},{"key":"10.1194\/jlr.M800538-JLR200_bib73","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1006\/bbrc.2001.4305","article-title":"Complete coding sequence, promoter region, and genomic structure of the human ABCA2 gene and evidence for sterol-dependent regulation in macrophages","volume":"281","author":"Kaminski","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1194\/jlr.M800538-JLR200_bib74","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/0020-711X(84)90120-4","article-title":"HMG-CoA reductase activity in the microsomal fraction from human placenta in early and term pregnancy","volume":"16","author":"Boguslawski","year":"1984","journal-title":"Int. J. Biochem."},{"key":"10.1194\/jlr.M800538-JLR200_bib75","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1210\/jcem-47-5-1099","article-title":"Regulation by plasma lipoproteins of progesterone biosynthesis and 3-hydroxy-3-methyl glutaryl coenzyme A reductase activity in cultured human choriocarcinoma cells","volume":"47","author":"Simpson","year":"1978","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1194\/jlr.M800538-JLR200_bib76","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/S0022-2275(20)39154-9","article-title":"Origin of cholesterol in the fetal Golden Syrian hamster: contribution of de novo sterol synthesis and maternal-derived lipoprotein cholesterol","volume":"37","author":"Woollett","year":"1996","journal-title":"J. Lipid Res."},{"key":"10.1194\/jlr.M800538-JLR200_bib77","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1172\/JCI113829","article-title":"Sterol synthesis and low density lipoprotein clearance in vivo in the pregnant rat, placenta, and fetus. Sources for tissue cholesterol during fetal development","volume":"82","author":"Belknap","year":"1988","journal-title":"J. Clin. Invest."},{"key":"10.1194\/jlr.M800538-JLR200_bib78","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1194\/jlr.M500306-JLR200","article-title":"A membrane defect in the pathogenesis of the Smith-Lemli-Opitz syndrome","volume":"47","author":"Tulenko","year":"2006","journal-title":"J. Lipid Res."},{"key":"10.1194\/jlr.M800538-JLR200_bib79","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1084\/jem.20051701","article-title":"Cholesterol deficiency in a mouse model of Smith-Lemli-Opitz syndrome reveals increased mast cell responsiveness","volume":"203","author":"Kovarova","year":"2006","journal-title":"J. Exp. Med."},{"key":"10.1194\/jlr.M800538-JLR200_bib80","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1194\/jlr.M300232-JLR200","article-title":"Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome","volume":"45","author":"Keller","year":"2004","journal-title":"J. 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