{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:33:55Z","timestamp":1792701235598,"version":"4.5.0"},"reference-count":346,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T00:00:00Z","timestamp":1600300800000},"content-version":"vor","delay-in-days":2270,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Lipid Research"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1194\/jlr.r046458","type":"journal-article","created":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T03:23:43Z","timestamp":1395199423000},"page":"1192-1214","source":"Crossref","is-referenced-by-count":676,"title":["LPA receptor signaling: pharmacology, physiology, and pathophysiology"],"prefix":"10.1016","volume":"55","author":[{"given":"Yun C.","family":"Yung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole C.","family":"Stoddard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerold","family":"Chun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1194\/jlr.R046458_bib1","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nrm2330","article-title":"Membrane lipids: where they are and how they behave","volume":"9","author":"van Meer","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1194\/jlr.R046458_bib2","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0006-2952(63)90074-1","article-title":"Pharamacologically active acidic phospholipids and glycolipids","volume":"12","author":"Vogt","year":"1963","journal-title":"Biochem. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib3","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1152\/ajplegacy.1968.214.2.337","article-title":"Antihypertensive effect of an isolated phospholipid","volume":"214","author":"Sen","year":"1968","journal-title":"Am. J. Physiol."},{"key":"10.1194\/jlr.R046458_bib4","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1007\/BF02533598","article-title":"Effects of synthetic and natural lysophosphatidic acids on the arterial blood pressure of different animal species","volume":"13","author":"Tokumura","year":"1978","journal-title":"Lipids."},{"key":"10.1194\/jlr.R046458_bib5","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/ddr.430040310","article-title":"Biologically active phospholipids as potential cardiovascular drugs","volume":"4","author":"Blankley","year":"1984","journal-title":"Drug Develop. Res."},{"key":"10.1194\/jlr.R046458_bib6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1042\/bj2790029","article-title":"High-density lipoproteins induce a rapid and transient release of Ca2+ in cultured fibroblasts","volume":"279","author":"P\u00f6rn","year":"1991","journal-title":"Biochem. J."},{"key":"10.1194\/jlr.R046458_bib7","first-page":"423","article-title":"Lysophosphatidic acids. Influence on platelet aggregation and intracellular calcium flux","volume":"96","author":"Gerrard","year":"1979","journal-title":"Am. J. Pathol."},{"key":"10.1194\/jlr.R046458_bib8","doi-asserted-by":"crossref","first-page":"C697","DOI":"10.1152\/ajpcell.1990.259.5.C697","article-title":"Platelet-activating factor and related acetylated lipids as potent biologically active cellular mediators","volume":"259","author":"Snyder","year":"1990","journal-title":"Am. J. Physiol."},{"key":"10.1194\/jlr.R046458_bib9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0092-8674(89)90868-4","article-title":"Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins","volume":"59","author":"van Corven","year":"1989","journal-title":"Cell."},{"key":"10.1194\/jlr.R046458_bib10","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1083\/jcb.135.4.1071","article-title":"Ventricu\u00adlar zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex","volume":"135","author":"Hecht","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1194\/jlr.R046458_bib11","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1124\/pr.110.003111","article-title":"International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature","volume":"62","author":"Chun","year":"2010","journal-title":"Pharmacol. Rev."},{"key":"10.1194\/jlr.R046458_bib12","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0014-5793(97)01301-X","article-title":"Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids","volume":"417","author":"An","year":"1997","journal-title":"FEBS Lett."},{"key":"10.1194\/jlr.R046458_bib13","doi-asserted-by":"crossref","first-page":"7906","DOI":"10.1074\/jbc.273.14.7906","article-title":"Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid","volume":"273","author":"An","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib14","doi-asserted-by":"crossref","first-page":"27776","DOI":"10.1074\/jbc.274.39.27776","article-title":"Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid","volume":"274","author":"Bandoh","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib15","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1146\/annurev.pharmtox.41.1.507","article-title":"Lysophospholipid receptors","volume":"41","author":"Fukushima","year":"2001","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1194\/jlr.R046458_bib16","doi-asserted-by":"crossref","first-page":"22105","DOI":"10.1074\/jbc.273.34.22105","article-title":"Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist","volume":"273","author":"Lee","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib17","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1126\/science.1470919","article-title":"Isolation and structure of a brain constituent that binds to the cannabinoid receptor","volume":"258","author":"Devane","year":"1992","journal-title":"Science."},{"key":"10.1194\/jlr.R046458_bib18","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1006\/bbrc.1995.2437","article-title":"2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain","volume":"215","author":"Sugiura","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1194\/jlr.R046458_bib19","doi-asserted-by":"crossref","first-page":"25600","DOI":"10.1074\/jbc.M302648200","article-title":"Identification of p2y9\/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family","volume":"278","author":"Noguchi","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib20","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1124\/jpet.105.098848","article-title":"Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes","volume":"318","author":"Kotarsky","year":"2006","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1194\/jlr.R046458_bib21","doi-asserted-by":"crossref","first-page":"23589","DOI":"10.1074\/jbc.M603670200","article-title":"GPR92 as a new G12\/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5","volume":"281","author":"Lee","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib22","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/ng.84","article-title":"G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth","volume":"40","author":"Pasternack","year":"2008","journal-title":"Nat. Genet."},{"key":"10.1194\/jlr.R046458_bib23","doi-asserted-by":"crossref","first-page":"17731","DOI":"10.1074\/jbc.M808506200","article-title":"Identification and characterization of a novel lysophosphatidic acid receptor, p2y5\/LPA6","volume":"284","author":"Yanagida","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib24","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.prostaglandins.2009.04.009","article-title":"Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol","volume":"89","author":"Makide","year":"2009","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1194\/jlr.R046458_bib25","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.2174\/092986708785747562","article-title":"LPA and its analogs-attractive tools for elucidation of LPA biology and drug development","volume":"15","author":"Kano","year":"2008","journal-title":"Curr. Med. Chem."},{"key":"10.1194\/jlr.R046458_bib26","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.bbalip.2008.06.005","article-title":"Two pathways for lysophosphatidic acid production","volume":"1781","author":"Aoki","year":"2008","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.R046458_bib27","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1083\/jcb.200407123","article-title":"A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells","volume":"169","author":"Bektas","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1194\/jlr.R046458_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0090-6980(01)00110-1","article-title":"Lysophosphatidic acid synthesis and release","volume":"64","author":"Pag\u00e8s","year":"2001","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1194\/jlr.R046458_bib29","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.biochi.2010.04.015","article-title":"Biological roles of lysophosphatidic acid signaling through its production by autotaxin","volume":"92","author":"Okudaira","year":"2010","journal-title":"Biochimie."},{"key":"10.1194\/jlr.R046458_bib30","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1073\/pnas.0135855100","article-title":"Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist","volume":"100","author":"McIntyre","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1194\/jlr.R046458_bib31","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.semcdb.2004.05.001","article-title":"Mechanisms of lysophosphatidic acid production","volume":"15","author":"Aoki","year":"2004","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1194\/jlr.R046458_bib32","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/S1388-1981(99)00127-4","article-title":"Occurrence of lysophosphatidic acid and its alkyl ether-linked analog in rat brain and comparison of their biological activities toward cultured neural cells","volume":"1440","author":"Sugiura","year":"1999","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.R046458_bib33","doi-asserted-by":"crossref","first-page":"48737","DOI":"10.1074\/jbc.M206812200","article-title":"Serum lysophosphatidic acid is produced through diverse phospholipase pathways","volume":"277","author":"Aoki","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib34","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1258\/acb.2008.007242","article-title":"Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity","volume":"45","author":"Hosogaya","year":"2008","journal-title":"Ann. Clin. Biochem."},{"key":"10.1194\/jlr.R046458_bib35","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1097\/01.mcg.0000225642.90898.0e","article-title":"Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C","volume":"41","author":"Watanabe","year":"2007","journal-title":"J. Clin. Gastroenterol."},{"key":"10.1194\/jlr.R046458_bib36","doi-asserted-by":"crossref","first-page":"21197","DOI":"10.1074\/jbc.M201289200","article-title":"Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood","volume":"277","author":"Sano","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib37","series-title":"In Lysophospholipid Receptors Signaling and Biochemistry.","first-page":"148","article-title":"Clinical introduction of lysophosphatidic acid (LPA) and autotaxin assays.","author":"Yatomi","year":"2013"},{"key":"10.1194\/jlr.R046458_bib38","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1373\/clinchem.2008.113779","article-title":"High-throughput analysis of sphingosine 1-phosphate, sphinganine 1-phosphate, and lysophosphatidic acid in plasma samples by liquid chromatography-tandem mass spectrometry","volume":"55","author":"Scherer","year":"2009","journal-title":"Clin. Chem."},{"key":"10.1194\/jlr.R046458_bib39","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0005-2760(86)90007-X","article-title":"Involvement of lysophospholipase D in the production of lysophosphatidic acid in rat plasma","volume":"875","author":"Tokumura","year":"1986","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.R046458_bib40","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1042\/bj2910677","article-title":"The bioactive phospholipid lysophosphatidic acid is released from activated platelets","volume":"291","author":"Eichholtz","year":"1993","journal-title":"Biochem. J."},{"key":"10.1194\/jlr.R046458_bib41","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.febslet.2004.06.083","article-title":"Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma","volume":"571","author":"Tanaka","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1194\/jlr.R046458_bib42","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1124\/jpet.109.164830","article-title":"Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain","volume":"333","author":"Ma","year":"2010","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1194\/jlr.R046458_bib43","doi-asserted-by":"crossref","first-page":"99ra87","DOI":"10.1126\/scitranslmed.3002095","article-title":"Lysophosphatidic acid signaling may initiate fetal hydrocephalus","volume":"3","author":"Yung","year":"2011","journal-title":"Sci. Transl. Med."},{"key":"10.1194\/jlr.R046458_bib44","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.prostaglandins.2012.01.003","article-title":"Lysophospholipids and lysophospholipase D in rabbit aqueous humor following corneal injury","volume":"97","author":"Tokumura","year":"2012","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1194\/jlr.R046458_bib45","doi-asserted-by":"crossref","first-page":"C1065","DOI":"10.1152\/ajpcell.1998.274.4.C1065","article-title":"Growth factor-like phospholipids generated after corneal injury","volume":"274","author":"Liliom","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1194\/jlr.R046458_bib46","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.bbalip.2008.05.008","article-title":"Roles of lysophosphatidic acid in cardiovascular physiology and disease","volume":"1781","author":"Smyth","year":"2008","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.R046458_bib47","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.jchromb.2010.03.030","article-title":"Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography-electrospray tandem mass spectrometry","volume":"878","author":"Aaltonen","year":"2010","journal-title":"J. Chromatogr. B Analyt. Technol. Biomed. Life Sci."},{"key":"10.1194\/jlr.R046458_bib48","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.chroma.2013.01.020","article-title":"Simultaneous profiling of polar lipids by supercritical fluid chromatography\/tandem mass spectrometry with methylation","volume":"1279","author":"Lee","year":"2013","journal-title":"J. Chromatogr. A."},{"key":"10.1194\/jlr.R046458_bib49","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.cca.2011.09.027","article-title":"Increased circulating plasma lysophosphatidic acid in patients with acute coronary syndrome","volume":"413","author":"Dohi","year":"2012","journal-title":"Clin. Chim. Acta."},{"key":"10.1194\/jlr.R046458_bib50","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/hep.25886","article-title":"Plasma lysophosphatidic acid levels and hepatocellular carcinoma","volume":"57","author":"Ikeda","year":"2013","journal-title":"Hepatology."},{"issue":"Suppl","key":"10.1194\/jlr.R046458_bib51","doi-asserted-by":"crossref","first-page":"S225","DOI":"10.1194\/jlr.R800055-JLR200","article-title":"Lipid phosphate phosphatases and signaling","volume":"50","author":"Brindley","year":"2009","journal-title":"J. Lipid Res."},{"key":"10.1194\/jlr.R046458_bib52","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1002\/jcb.20128","article-title":"Lysophospholipids in development: miles apart and edging in","volume":"92","author":"Saba","year":"2004","journal-title":"J. Cell. Biochem."},{"key":"10.1194\/jlr.R046458_bib53","doi-asserted-by":"crossref","first-page":"5121","DOI":"10.1021\/cr200433m","article-title":"Unlike two peas in a pod: lipid phosphate phosphatases and phosphatidate phosphatases","volume":"112","author":"Kok","year":"2012","journal-title":"Chem. Rev."},{"key":"10.1194\/jlr.R046458_bib54","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1038\/nn1052","article-title":"A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting","volume":"6","author":"Br\u00e4uer","year":"2003","journal-title":"Nat. Neurosci."},{"key":"10.1194\/jlr.R046458_bib55","doi-asserted-by":"crossref","first-page":"2524","DOI":"10.1016\/S0021-9258(18)45911-X","article-title":"Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein","volume":"267","author":"Stracke","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib56","doi-asserted-by":"crossref","first-page":"39436","DOI":"10.1074\/jbc.M205623200","article-title":"Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase","volume":"277","author":"Tokumura","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib57","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1083\/jcb.200204026","article-title":"Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production","volume":"158","author":"Umezu-Goto","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1194\/jlr.R046458_bib58","doi-asserted-by":"crossref","first-page":"24408","DOI":"10.1074\/jbc.271.40.24408","article-title":"Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin","volume":"271","author":"Lee","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib59","doi-asserted-by":"crossref","first-page":"17634","DOI":"10.1074\/jbc.M313927200","article-title":"Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1","volume":"279","author":"Hama","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib60","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0925-4773(99)00048-9","article-title":"Developmental expression analysis of murine autotaxin (ATX)","volume":"84","author":"B\u00e4chner","year":"1999","journal-title":"Mech. Dev."},{"key":"10.1194\/jlr.R046458_bib61","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1006\/bbrc.1996.0127","article-title":"Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells","volume":"218","author":"Lee","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1194\/jlr.R046458_bib62","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s00018-006-6412-0","article-title":"Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma","volume":"64","author":"Savaskan","year":"2007","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1194\/jlr.R046458_bib63","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.cca.2009.04.025","article-title":"Autotaxin enzyme immunoassay in human cerebrospinal fluid samples","volume":"405","author":"Nakamura","year":"2009","journal-title":"Clin. Chim. Acta."},{"key":"10.1194\/jlr.R046458_bib64","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.2353\/ajpath.2008.071153","article-title":"Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions","volume":"173","author":"Nakasaki","year":"2008","journal-title":"Am. J. Pathol."},{"key":"10.1194\/jlr.R046458_bib65","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/ni1573","article-title":"Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs","volume":"9","author":"Kanda","year":"2008","journal-title":"Nat. Immunol."},{"key":"10.1194\/jlr.R046458_bib66","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.4049\/jimmunol.1202025","article-title":"Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin\/lysophosphatidic acid axis","volume":"190","author":"Bai","year":"2013","journal-title":"J. Immunol."},{"key":"10.1194\/jlr.R046458_bib67","doi-asserted-by":"crossref","first-page":"25822","DOI":"10.1074\/jbc.M605142200","article-title":"Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid","volume":"281","author":"Tanaka","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib68","doi-asserted-by":"crossref","first-page":"5015","DOI":"10.1128\/MCB.02419-05","article-title":"Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development","volume":"26","author":"van Meeteren","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1194\/jlr.R046458_bib69","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.bbrc.2010.08.008","article-title":"Deficiency of autotaxin\/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway","volume":"400","author":"Koike","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1194\/jlr.R046458_bib70","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1002\/iub.220","article-title":"Lysophosphatidic acid in vascular development and disease","volume":"61","author":"Teo","year":"2009","journal-title":"IUBMB Life."},{"key":"10.1194\/jlr.R046458_bib71","doi-asserted-by":"crossref","first-page":"852","DOI":"10.2741\/4148","article-title":"Regulation of angiogenesis by phospholipid lysophosphatidic acid","volume":"18","author":"Chen","year":"2013","journal-title":"Front. Biosci. (Landmark Ed)."},{"key":"10.1194\/jlr.R046458_bib72","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0022-2143(97)90141-4","article-title":"Endothelial cell mitogenesis induced by LPA: inhibition by thrombospondin-1 and thrombospondin-2","volume":"129","author":"Panetti","year":"1997","journal-title":"J. Lab. Clin. Med."},{"key":"10.1194\/jlr.R046458_bib73","doi-asserted-by":"crossref","first-page":"C612","DOI":"10.1152\/ajpcell.2000.278.3.C612","article-title":"Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing","volume":"278","author":"Lee","year":"2000","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1194\/jlr.R046458_bib74","first-page":"351010","article-title":"Interleukin-1\u03b2 expression is required for lysophosphatidic acid-induced lymphangiogenesis in human umbilical vein endothelial cells","volume":"2011","author":"Lin","year":"2011","journal-title":"Int. J. Inflam."},{"key":"10.1194\/jlr.R046458_bib75","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1089\/152581699319795","article-title":"Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis","volume":"8","author":"English","year":"1999","journal-title":"J. Hematother. Stem Cell Res."},{"key":"10.1194\/jlr.R046458_bib76","doi-asserted-by":"crossref","first-page":"6931","DOI":"10.1073\/pnas.96.12.6931","article-title":"Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions","volume":"96","author":"Siess","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1194\/jlr.R046458_bib77","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1146\/annurev.biochem.73.011303.073731","article-title":"Lysophospholipid receptors: signaling and biology","volume":"73","author":"Ishii","year":"2004","journal-title":"Annu. Rev. Biochem."},{"key":"10.1194\/jlr.R046458_bib78","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.semcdb.2004.05.005","article-title":"Cell surface receptors in lysophospholipid signaling","volume":"15","author":"Anliker","year":"2004","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1194\/jlr.R046458_bib79","doi-asserted-by":"crossref","first-page":"38418","DOI":"10.1074\/jbc.M601670200","article-title":"Lipid phosphate phosphatase-1 regulates lysophosphatidate-induced fibroblast migration by controlling phospholipase D2-dependent phosphatidate generation","volume":"281","author":"Pilquil","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib80","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1128\/MCB.00038-13","article-title":"Distinct phospholipase C-beta isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure","volume":"33","author":"Lee","year":"2013","journal-title":"Mol. Cell. Biol."},{"key":"10.1194\/jlr.R046458_bib81","first-page":"H2048","article-title":"Lysophosphatidic acid alters cerebrovascular reactivity in piglets","volume":"268","author":"Tigyi","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1194\/jlr.R046458_bib82","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1096\/fj.13-234997","article-title":"Lysophosphatidic acid induces vasodilation mediated by LPA1 receptors, phospholipase C, and endothelial nitric oxide synthase","volume":"28","author":"Ruisanchez","year":"2014","journal-title":"FASEB J."},{"key":"10.1194\/jlr.R046458_bib83","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1124\/pr.112.007179","article-title":"International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands","volume":"65","author":"Davenport","year":"2013","journal-title":"Pharmacol. Rev."},{"key":"10.1194\/jlr.R046458_bib84","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1006\/geno.1998.5400","article-title":"Complete cDNA sequence, genomic structure, and chromosomal localization of the LPA receptor gene, lpA1\/vzg-1\/Gpcr26","volume":"51","author":"Contos","year":"1998","journal-title":"Genomics."},{"key":"10.1194\/jlr.R046458_bib85","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.3390\/ijms14022788","article-title":"Structural characterization of an LPA1 second extracellular loop mimetic with a self-assembling coiled-coil folding constraint","volume":"14","author":"Young","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1194\/jlr.R046458_bib86","doi-asserted-by":"crossref","first-page":"12175","DOI":"10.1074\/jbc.M708847200","article-title":"Subtype-specific residues involved in ligand activation of the endothelial differentiation gene family lysophosphatidic acid receptors","volume":"283","author":"Valentine","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib87","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1124\/mol.58.6.1188","article-title":"Lysophosphatidic acid receptors","volume":"58","author":"Contos","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib88","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/humupd\/dmn023","article-title":"Lysophospholipid signaling in the function and pathology of the reproductive system","volume":"14","author":"Ye","year":"2008","journal-title":"Hum. Reprod. Update."},{"key":"10.1194\/jlr.R046458_bib89","doi-asserted-by":"crossref","first-page":"3280","DOI":"10.1002\/dvdy.21736","article-title":"Expression patterns of the lysophospholipid receptor genes during mouse early development","volume":"237","author":"Ohuchi","year":"2008","journal-title":"Dev. Dyn."},{"key":"10.1194\/jlr.R046458_bib90","doi-asserted-by":"crossref","first-page":"13384","DOI":"10.1073\/pnas.97.24.13384","article-title":"Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior","volume":"97","author":"Contos","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1194\/jlr.R046458_bib91","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1046\/j.1460-9568.1998.00117.x","article-title":"A rat G protein-coupled receptor selectively expressed in myelin-forming cells","volume":"10","author":"Allard","year":"1998","journal-title":"Eur. J. Neurosci."},{"key":"10.1194\/jlr.R046458_bib92","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1002\/(SICI)1096-9861(19980907)398:4<587::AID-CNE10>3.0.CO;2-5","article-title":"Lysophosphatidic acid receptor gene vzg-1\/lpA1\/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain","volume":"398","author":"Weiner","year":"1998","journal-title":"J. Comp. Neurol."},{"key":"10.1194\/jlr.R046458_bib93","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1093\/cercor\/bhm132","article-title":"Absence of LPA1 signaling results in defective cortical development","volume":"18","author":"Estivill-Torr\u00fas","year":"2008","journal-title":"Cereb. Cortex."},{"key":"10.1194\/jlr.R046458_bib94","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.mcn.2003.09.001","article-title":"LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease","volume":"24","author":"Harrison","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1194\/jlr.R046458_bib95","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1038\/nn1157","article-title":"Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding","volume":"6","author":"Kingsbury","year":"2003","journal-title":"Nat. Neurosci."},{"key":"10.1194\/jlr.R046458_bib96","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/S0896-6273(01)00551-7","article-title":"Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation","volume":"32","author":"Campbell","year":"2001","journal-title":"Neuron."},{"key":"10.1194\/jlr.R046458_bib97","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1006\/dbio.2000.9930","article-title":"Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology","volume":"228","author":"Fukushima","year":"2000","journal-title":"Dev. Biol."},{"key":"10.1194\/jlr.R046458_bib98","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/ncb895","article-title":"Signalling and crosstalk of Rho GTPases in mediating axon guidance","volume":"5","author":"Yuan","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"10.1194\/jlr.R046458_bib99","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1006\/mcne.2002.1123","article-title":"Lysophosphatidic acid influences the morphology and motility of young, postmitotic cortical neurons","volume":"20","author":"Fukushima","year":"2002","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1194\/jlr.R046458_bib100","doi-asserted-by":"crossref","first-page":"7069","DOI":"10.1523\/JNEUROSCI.21-18-07069.2001","article-title":"Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling","volume":"21","author":"Weiner","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1194\/jlr.R046458_bib101","first-page":"247","article-title":"Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action","volume":"4","author":"Jalink","year":"1993","journal-title":"Cell Growth Differ."},{"key":"10.1194\/jlr.R046458_bib102","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1046\/j.1471-4159.1996.66020537.x","article-title":"Lysophosphatidic acid-induced neurite retraction in PC12 cells: control by phosphoinositide-Ca2+ signaling and Rho","volume":"66","author":"Tigyi","year":"1996","journal-title":"J. Neurochem."},{"key":"10.1194\/jlr.R046458_bib103","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/(SICI)1097-4547(19980915)53:6<685::AID-JNR7>3.0.CO;2-1","article-title":"Lysophosphatidic acid and apoptosis of nerve growth factor-differentiated PC12 cells","volume":"53","author":"Holtsberg","year":"1998","journal-title":"J. Neurosci. Res."},{"key":"10.1194\/jlr.R046458_bib104","first-page":"163","article-title":"Dual action of lysophosphatidic acid in cultured cortical neurons: survival and apoptogenic","volume":"56","author":"Zheng","year":"2004","journal-title":"Sheng Li Xue Bao."},{"key":"10.1194\/jlr.R046458_bib105","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1749-6632.2000.tb06545.x","article-title":"Lysophosphatidic acid induction of neuronal apoptosis and necrosis","volume":"905","author":"Steiner","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1194\/jlr.R046458_bib106","doi-asserted-by":"crossref","first-page":"6151","DOI":"10.1073\/pnas.95.11.6151","article-title":"A single receptor encoded by vzg-1\/lpA1\/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid","volume":"95","author":"Fukushima","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1194\/jlr.R046458_bib107","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1089\/scd.2004.13.685","article-title":"Lysophosphatidic acid induces clonal generation of mouse neurospheres via proliferation of Sca-1- and AC133-positive neural progenitors","volume":"13","author":"Svetlov","year":"2004","journal-title":"Stem Cells Dev."},{"key":"10.1194\/jlr.R046458_bib108","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1242\/dev.01618","article-title":"Lysophosphatidic acid signaling controls cortical actin assembly and cytoarchitecture in Xenopus embryos","volume":"132","author":"Lloyd","year":"2005","journal-title":"Development."},{"key":"10.1194\/jlr.R046458_bib109","doi-asserted-by":"crossref","first-page":"e49227","DOI":"10.1371\/journal.pone.0049227","article-title":"The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA","volume":"7","author":"Varsano","year":"2012","journal-title":"PLoS ONE."},{"key":"10.1194\/jlr.R046458_bib110","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.cell.2012.06.037","article-title":"Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling","volume":"150","author":"Yu","year":"2012","journal-title":"Cell."},{"key":"10.1194\/jlr.R046458_bib111","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1478-811X-11-31","article-title":"The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells","volume":"11","author":"Cai","year":"2013","journal-title":"Cell Commun. Signal."},{"key":"10.1194\/jlr.R046458_bib112","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.mcn.2008.07.014","article-title":"Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus","volume":"39","author":"Matas-Rico","year":"2008","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1194\/jlr.R046458_bib113","doi-asserted-by":"crossref","unstructured":".PedrazaC.Sanchez-LopezJ.Castilla-OrtegaE.Rosell-ValleC.Zambrana-InfantesE.Garcia-FernandezM.Rodriguez de FonsecaF.ChunJ.SantinL. J.Estivill-TorrusG.. Fear extinction and acute stress reactivity reveal a role of LPA receptor in regulating emotional-like behaviors. Brain Struct. Funct. Epub ahead of print. June 18, 2013; doi:10.1007\/s00429-013-0592-9.","DOI":"10.1007\/s00429-013-0592-9"},{"key":"10.1194\/jlr.R046458_bib114","doi-asserted-by":"crossref","first-page":"e25522","DOI":"10.1371\/journal.pone.0025522","article-title":"Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA(1) receptor knockout mice","volume":"6","author":"Castilla-Ortega","year":"2011","journal-title":"PLoS ONE."},{"key":"10.1194\/jlr.R046458_bib115","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/tpj.2010.44","article-title":"Systematic generation of in vivo G protein-coupled receptor mutants in the rat","volume":"11","author":"van Boxtel","year":"2011","journal-title":"Pharmacogenomics J."},{"key":"10.1194\/jlr.R046458_bib116","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.tins.2003.08.008","article-title":"New roles for astrocytes: redefining the functional architecture of the brain","volume":"26","author":"Nedergaard","year":"2003","journal-title":"Trends Neurosci."},{"key":"10.1194\/jlr.R046458_bib117","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/glia.10054","article-title":"Immunohistological localization of the myelinating cell-specific receptor LP(A1)","volume":"38","author":"Cervera","year":"2002","journal-title":"Glia."},{"key":"10.1194\/jlr.R046458_bib118","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.neuint.2007.07.004","article-title":"Lysophosphatidic acid stimulates astrocyte proliferation through LPA1","volume":"52","author":"Shano","year":"2008","journal-title":"Neurochem. Int."},{"key":"10.1194\/jlr.R046458_bib119","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/(SICI)1098-1136(199706)20:2<163::AID-GLIA8>3.0.CO;2-A","article-title":"Bovine serum albumin and lysophosphatidic acid stimulate calcium mobilization and reversal of cAMP-induced stellation in rat spinal cord astrocytes","volume":"20","author":"Manning","year":"1997","journal-title":"Glia."},{"key":"10.1194\/jlr.R046458_bib120","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/(SICI)1098-1136(199710)21:2<244::AID-GLIA7>3.0.CO;2-6","article-title":"Astrocyte spreading in response to thrombin and lysophosphatidic acid is dependent on the Rho GTPase","volume":"21","author":"Suidan","year":"1997","journal-title":"Glia."},{"key":"10.1194\/jlr.R046458_bib121","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0006-8993(03)03527-3","article-title":"Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes","volume":"990","author":"Rao","year":"2003","journal-title":"Brain Res."},{"key":"10.1194\/jlr.R046458_bib122","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1124\/mol.64.5.1199","article-title":"Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes","volume":"64","author":"Sorensen","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib123","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/j.1471-4159.2011.07188.x","article-title":"Unmasking of LPA1 receptor-mediated migration response to lysophosphatidic acid by interleukin-1\u03b2-induced attenuation of Rho signaling pathways in rat astrocytes","volume":"117","author":"Sato","year":"2011","journal-title":"J. Neurochem."},{"key":"10.1194\/jlr.R046458_bib124","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.coph.2008.11.010","article-title":"Lysophosphatidic acid (LPA) and its receptors","volume":"9","author":"Noguchi","year":"2009","journal-title":"Curr. Opin. Phar\u00admacol."},{"key":"10.1194\/jlr.R046458_bib125","doi-asserted-by":"crossref","first-page":"7470","DOI":"10.1074\/jbc.M707758200","article-title":"Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiation","volume":"283","author":"Spohr","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib126","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1471-4159.2011.07421.x","article-title":"Astrocytes treated by lysophosphatidic acid induce axonal outgrowth of cortical progenitors through extracellular matrix protein and epidermal growth factor signaling pathway","volume":"119","author":"de Sampaio e Spohr","year":"2011","journal-title":"J. Neurochem."},{"key":"10.1194\/jlr.R046458_bib127","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s11010-007-9524-4","article-title":"Production of nerve growth factor enhanced in cultured mouse astrocytes by glycerophospholipids, sphingolipids, and their related compounds","volume":"305","author":"Furukawa","year":"2007","journal-title":"Mol. Cell. Biochem."},{"key":"10.1194\/jlr.R046458_bib128","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/glia.10297","article-title":"Characterization of lysophosphatidic acid and sphingosine-1-phosphate-mediated signal transduction in rat cortical oligodendrocytes","volume":"45","author":"Yu","year":"2004","journal-title":"Glia."},{"key":"10.1194\/jlr.R046458_bib129","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1006\/mcne.2002.1129","article-title":"Oligodendroglial expression of Edg-2 receptor: developmental analysis and pharmacological responses to lysophosphatidic acid","volume":"20","author":"Stankoff","year":"2002","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1194\/jlr.R046458_bib130","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1046\/j.1471-4159.2003.02056.x","article-title":"Lyso\u00adphosphatidic acid induces process retraction in CG-4 line oligodendrocytes and oligodendrocyte precursor cells but not in differentiated oligodendrocytes","volume":"87","author":"Dawson","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1194\/jlr.R046458_bib131","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/s11064-008-9772-z","article-title":"Lysophosphatidic acid can support the formation of membranous structures and an increase in MBP mRNA levels in differentiating oligodendrocytes","volume":"34","author":"Nogaroli","year":"2009","journal-title":"Neurochem. Res."},{"key":"10.1194\/jlr.R046458_bib132","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1267\/ahc.06002","article-title":"Lysophospholipid receptors are differentially expressed in rat terminal Schwann cells, as revealed by a single cell rt-PCR and in situ hybridization","volume":"39","author":"Kobashi","year":"2006","journal-title":"Acta Histochem. Cytochem."},{"key":"10.1194\/jlr.R046458_bib133","doi-asserted-by":"crossref","first-page":"5233","DOI":"10.1073\/pnas.96.9.5233","article-title":"Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid","volume":"96","author":"Weiner","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1194\/jlr.R046458_bib134","doi-asserted-by":"crossref","first-page":"9585","DOI":"10.1074\/jbc.M213244200","article-title":"Lysophosphatidic acid promotes survival and differentiation of rat Schwann cells","volume":"278","author":"Li","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib135","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1002\/glia.22572","article-title":"Lysophosphatidic acid (LPA) and its receptor, LPA1, influence embryonic Schwann cell migration, myelination, and cell-to-axon segregation","volume":"61","author":"Anliker","year":"2013","journal-title":"Glia."},{"key":"10.1194\/jlr.R046458_bib136","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1006\/geno.2000.6122","article-title":"Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)\/Edg4, and identification of a frameshift mutation in a previously characterized cDNA","volume":"64","author":"Contos","year":"2000","journal-title":"Genomics."},{"key":"10.1194\/jlr.R046458_bib137","doi-asserted-by":"crossref","first-page":"e1000582","DOI":"10.1371\/journal.pbio.1000582","article-title":"A high-resolution anatomical atlas of the transcriptome in the mouse embryo","volume":"9","author":"Diez-Roux","year":"2011","journal-title":"PLoS Biol."},{"key":"10.1194\/jlr.R046458_bib138","doi-asserted-by":"crossref","first-page":"7300","DOI":"10.1523\/JNEUROSCI.6151-09.2010","article-title":"Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis","volume":"30","author":"Dubin","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1194\/jlr.R046458_bib139","doi-asserted-by":"crossref","first-page":"e86","DOI":"10.1371\/journal.pbio.0040086","article-title":"BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system","volume":"4","author":"Magdaleno","year":"2006","journal-title":"PLoS Biol."},{"key":"10.1194\/jlr.R046458_bib140","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1146\/annurev.pharmtox.010909.105753","article-title":"LPA receptors: subtypes and biological actions","volume":"50","author":"Choi","year":"2010","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1194\/jlr.R046458_bib141","doi-asserted-by":"crossref","first-page":"5859","DOI":"10.1128\/MCB.25.14.5859-5868.2005","article-title":"c-Src-mediated phosphorylation of TRIP6 regulates its function in lysophosphatidic acid-induced cell migration","volume":"25","author":"Lai","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1194\/jlr.R046458_bib142","doi-asserted-by":"crossref","first-page":"24381","DOI":"10.1074\/jbc.M701499200","article-title":"PTPL1\/FAP-1 negatively regulates TRIP6 function in lysophosphatidic acid-induced cell migration","volume":"282","author":"Lai","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib143","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.bbalip.2008.04.013","article-title":"Regulation of the LPA2 receptor signaling through the carboxyl-terminal tail-mediated protein-protein interactions","volume":"1781","author":"Lin","year":"2008","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.R046458_bib144","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1093\/carcin\/bgp011","article-title":"LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites","volume":"30","author":"Komachi","year":"2009","journal-title":"Carcinogenesis."},{"key":"10.1194\/jlr.R046458_bib145","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1038\/sj.onc.1204192","article-title":"Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission","volume":"20","author":"Gschwind","year":"2001","journal-title":"Oncogene."},{"key":"10.1194\/jlr.R046458_bib146","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S1388-1981(02)00172-5","article-title":"In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice","volume":"1582","author":"Yang","year":"2002","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.R046458_bib147","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1038\/nm1060","article-title":"Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling","volume":"10","author":"Inoue","year":"2004","journal-title":"Nat. Med."},{"key":"10.1194\/jlr.R046458_bib148","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1016\/j.cell.2009.06.050","article-title":"Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling","volume":"138","author":"Trimbuch","year":"2009","journal-title":"Cell."},{"key":"10.1194\/jlr.R046458_bib149","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1161\/CIRCRESAHA.108.180778","article-title":"Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure","volume":"103","author":"Panchatcharam","year":"2008","journal-title":"Circ. Res."},{"key":"10.1194\/jlr.R046458_bib150","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1549-8719.2010.00001.x","article-title":"Regulation of cerebromicrovascular permeability by lysophosphatidic acid","volume":"17","author":"Sarker","year":"2010","journal-title":"Micro\u00adcirculation."},{"key":"10.1194\/jlr.R046458_bib151","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1161\/CIRCRESAHA.109.212647","article-title":"Lysophosphatidic acid receptors LPA1 and LPA3 promote CXCL12-mediated smooth muscle progenitor cell recruitment in neointima formation","volume":"107","author":"Subramanian","year":"2010","journal-title":"Circ. Res."},{"key":"10.1194\/jlr.R046458_bib152","doi-asserted-by":"crossref","first-page":"4129","DOI":"10.4049\/jimmunol.169.8.4129","article-title":"The influence of lysophosphatidic acid on the functions of human dendritic cells","volume":"169","author":"Panther","year":"2002","journal-title":"J. Immunol."},{"key":"10.1194\/jlr.R046458_bib153","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1089\/scd.2006.15.797","article-title":"Lysophosphatidic acid modulates the activation of human monocyte-derived dendritic cells","volume":"15","author":"Chen","year":"2006","journal-title":"Stem Cells Dev."},{"key":"10.1194\/jlr.R046458_bib154","doi-asserted-by":"crossref","first-page":"21054","DOI":"10.1074\/jbc.M708908200","article-title":"Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92","volume":"283","author":"Oh","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib155","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.4049\/jimmunol.166.4.2317","article-title":"Lysophosphatidic acid receptor-selective effects on Jurkat T cell migration through a Matrigel model basement membrane","volume":"166","author":"Zheng","year":"2001","journal-title":"J. Immunol."},{"key":"10.1194\/jlr.R046458_bib156","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1096\/fj.00-0492fje","article-title":"Altered expression and functional profile of lysophosphatidic acid receptors in mitogen-activated human blood T lymphocytes","volume":"14","author":"Zheng","year":"2000","journal-title":"FASEB J."},{"key":"10.1194\/jlr.R046458_bib157","doi-asserted-by":"crossref","first-page":"L66","DOI":"10.1152\/ajplung.00473.2004","article-title":"Lysophosphatidic acid enhances interleukin-13 gene expression and promoter activity in T cells","volume":"290","author":"Rubenfeld","year":"2006","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1194\/jlr.R046458_bib158","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1189\/jlb.0407221","article-title":"LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA)","volume":"82","author":"Chan","year":"2007","journal-title":"J. Leukoc. Biol."},{"key":"10.1194\/jlr.R046458_bib159","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.4049\/jimmunol.1102956","article-title":"Lpa2 is a negative regulator of both dendritic cell activation and murine models of allergic lung inflammation","volume":"188","author":"Emo","year":"2012","journal-title":"J. Immunol."},{"key":"10.1194\/jlr.R046458_bib160","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1124\/mol.57.4.753","article-title":"Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate","volume":"57","author":"Im","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib161","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1124\/mol.58.5.895","article-title":"Functional comparisons of the lysophosphatidic acid receptors, LP(A1)\/VZG-1\/EDG-2, LP(A2)\/EDG-4, and LP(A3)\/EDG-7 in neuronal cell lines using a retrovirus expression system","volume":"58","author":"Ishii","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib162","doi-asserted-by":"crossref","first-page":"34254","DOI":"10.1074\/jbc.M201659200","article-title":"A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid","volume":"277","author":"Sonoda","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib163","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/nature03505","article-title":"LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing","volume":"435","author":"Ye","year":"2005","journal-title":"Nature."},{"key":"10.1194\/jlr.R046458_bib164","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.domaniend.2011.08.003","article-title":"Lysophosphatidic acid receptors in ovine uterus during estrous cycle and early pregnancy and their regulation by progesterone","volume":"42","author":"Liszewska","year":"2012","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1194\/jlr.R046458_bib165","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.lfs.2006.06.002","article-title":"Lysophosphatidic receptor, LPA3, is positively and negatively regulated by progesterone and estrogen in the mouse uterus","volume":"79","author":"Hama","year":"2006","journal-title":"Life Sci."},{"key":"10.1194\/jlr.R046458_bib166","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1095\/biolreprod61.1.195","article-title":"Production of lysophosphatidic acids by lysophospholipase D in human follicular fluids of in vitro fertilization patients","volume":"61","author":"Tokumura","year":"1999","journal-title":"Biol. Reprod."},{"key":"10.1194\/jlr.R046458_bib167","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1600-0897.2009.00715.x","article-title":"Expression of autotaxin, an ectoenzyme that produces lysophosphatidic acid, in human placenta","volume":"62","author":"Iwasawa","year":"2009","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1194\/jlr.R046458_bib168","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1016\/j.cca.2011.06.039","article-title":"Serum autotaxin measurements in pregnant women: application for the differentiation of normal pregnancy and pregnancy-induced hypertension","volume":"412","author":"Masuda","year":"2011","journal-title":"Clin. Chim. Acta."},{"key":"10.1194\/jlr.R046458_bib169","doi-asserted-by":"crossref","first-page":"4439","DOI":"10.1242\/dev.081745","article-title":"Autotaxin\/Lpar3 signaling regulates Kupffer's vesicle formation and left-right asymmetry in zebrafish","volume":"139","author":"Lai","year":"2012","journal-title":"Development."},{"key":"10.1194\/jlr.R046458_bib170","doi-asserted-by":"crossref","first-page":"4310","DOI":"10.1074\/jbc.M610826200","article-title":"LPA(4)\/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)\/G(i)-mediated calcium signaling and G(12\/13)-mediated Rho activation","volume":"282","author":"Lee","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib171","doi-asserted-by":"crossref","first-page":"5814","DOI":"10.1074\/jbc.M610767200","article-title":"LPA4\/p2y9\/GPR23 mediates rho-dependent morphological changes in a rat neuronal cell line","volume":"282","author":"Yanagida","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib172","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/01.wnr.0000209011.16718.68","article-title":"Lysophosphatidic acid stimulates cAMP accumulation and cAMP response element-binding protein phosphorylation in immortalized hippocampal progenitor cells","volume":"17","author":"Rhee","year":"2006","journal-title":"Neuroreport."},{"key":"10.1194\/jlr.R046458_bib173","doi-asserted-by":"crossref","first-page":"5435","DOI":"10.1091\/mbc.e08-03-0316","article-title":"Role of LPA4\/p2y9\/GPR23 in negative regulation of cell motility","volume":"19","author":"Lee","year":"2008","journal-title":"Mol. Biol. Cell."},{"key":"10.1194\/jlr.R046458_bib174","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.biomaterials.2009.09.035","article-title":"The synergistic effects of lysophosphatidic acid receptor agonists and calcitriol on MG63 osteoblast maturation at titanium and hydroxyapatite surfaces","volume":"31","author":"Mansell","year":"2010","journal-title":"Biomaterials."},{"key":"10.1194\/jlr.R046458_bib175","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.ccr.2009.03.027","article-title":"Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases","volume":"15","author":"Liu","year":"2009","journal-title":"Cancer Cell."},{"key":"10.1194\/jlr.R046458_bib176","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.bone.2011.04.018","article-title":"Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass","volume":"49","author":"Gennero","year":"2011","journal-title":"Bone."},{"key":"10.1194\/jlr.R046458_bib177","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1002\/jcb.22471","article-title":"LPA induces osteoblast differentiation through interplay of two receptors: LPA1 and LPA4","volume":"109","author":"Liu","year":"2010","journal-title":"J. Cell. Biochem."},{"key":"10.1194\/jlr.R046458_bib178","doi-asserted-by":"crossref","first-page":"5060","DOI":"10.1182\/blood-2010-03-272443","article-title":"LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis","volume":"116","author":"Sumida","year":"2010","journal-title":"Blood."},{"key":"10.1194\/jlr.R046458_bib179","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s11745-013-3765-7","article-title":"Lysophosphatidic acid produced by hen egg white lysophospholipase D induces vascular development on extraembryonic membranes","volume":"48","author":"Morishige","year":"2013","journal-title":"Lipids."},{"key":"10.1194\/jlr.R046458_bib180","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.thromres.2007.08.014","article-title":"Gene expression profiling for the identification of G-protein coupled receptors in human platelets","volume":"122","author":"Amisten","year":"2008","journal-title":"Thromb. Res."},{"key":"10.1194\/jlr.R046458_bib181","doi-asserted-by":"crossref","first-page":"e18192","DOI":"10.1371\/journal.pone.0018192","article-title":"LPA5 is abundantly expressed by human mast cells and important for lysophosphatidic acid induced MIP-1\u03b2 release","volume":"6","author":"Lundequist","year":"2011","journal-title":"PLoS ONE."},{"key":"10.1194\/jlr.R046458_bib182","doi-asserted-by":"crossref","first-page":"17304","DOI":"10.1074\/jbc.M109.003194","article-title":"Unique ligand selectivity of the GPR92\/LPA5 lysophosphatidate receptor indicates role in human platelet activation","volume":"284","author":"Williams","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib183","doi-asserted-by":"crossref","first-page":"e29260","DOI":"10.1371\/journal.pone.0029260","article-title":"LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor","volume":"6","author":"Jongsma","year":"2011","journal-title":"PLoS ONE."},{"key":"10.1194\/jlr.R046458_bib184","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1053\/j.gastro.2009.09.055","article-title":"Lysophosphatidic acid stimulates the intestinal brush border Na(+)\/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2","volume":"138","author":"Lin","year":"2010","journal-title":"Gastroenterology."},{"key":"10.1194\/jlr.R046458_bib185","doi-asserted-by":"crossref","first-page":"628","DOI":"10.4049\/jimmunol.151.2.628","article-title":"Identification of a G protein coupled receptor induced in activated T cells","volume":"151","author":"Kaplan","year":"1993","journal-title":"J. Immunol."},{"key":"10.1194\/jlr.R046458_bib186","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1006\/bbrc.1996.0189","article-title":"Identification of 6H1 as a P2Y purinoceptor: P2Y5","volume":"219","author":"Webb","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1194\/jlr.R046458_bib187","doi-asserted-by":"crossref","first-page":"G641","DOI":"10.1152\/ajpgi.00191.2009","article-title":"P2Y5 is a G(alpha)i, G(alpha)12\/13 G protein-coupled receptor activated by lysophosphatidic acid that reduces intestinal cell adhesion","volume":"297","author":"Lee","year":"2009","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1194\/jlr.R046458_bib188","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.1600-0625.2008.00788.x","article-title":"Autosomal recessive woolly hair with hypotrichosis caused by a novel homozygous mutation in the P2RY5 gene","volume":"18","author":"Shimomura","year":"2009","journal-title":"Exp. Dermatol."},{"key":"10.1194\/jlr.R046458_bib189","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1365-2230.2010.03944.x","article-title":"A novel mutation in LPAR6 causes autosomal recessive hypotrichosis of the scalp","volume":"36","author":"Nahum","year":"2011","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1194\/jlr.R046458_bib190","doi-asserted-by":"crossref","first-page":"2772","DOI":"10.1038\/jid.2009.154","article-title":"In vitro analysis of LIPH mutations causing hypotrichosis simplex: evidence confirming the role of lipase H and lysophosphatidic acid in hair growth","volume":"129","author":"Pasternack","year":"2009","journal-title":"J. Invest. Dermatol."},{"key":"10.1194\/jlr.R046458_bib191","first-page":"602","article-title":"Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis","volume":"31","author":"Shinkuma","year":"2010","journal-title":"Hum. Mutat."},{"key":"10.1194\/jlr.R046458_bib192","doi-asserted-by":"crossref","first-page":"4248","DOI":"10.1038\/emboj.2011.296","article-title":"LPA-producing enzyme PA-PLA(1)\u03b1 regulates hair follicle development by modulating EGFR signalling","volume":"30","author":"Inoue","year":"2011","journal-title":"EMBO J."},{"key":"10.1194\/jlr.R046458_bib193","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/cmdc.200600280","article-title":"Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA","volume":"2","author":"Jiang","year":"2007","journal-title":"ChemMedChem."},{"key":"10.1194\/jlr.R046458_bib194","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1021\/ol7030747","article-title":"Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid","volume":"10","author":"Gajewiak","year":"2008","journal-title":"Org. Lett."},{"key":"10.1194\/jlr.R046458_bib195","doi-asserted-by":"crossref","first-page":"5441","DOI":"10.1158\/0008-5472.CAN-09-0302","article-title":"Dual activity lysophosphatidic acid receptor pan-antagonist\/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo","volume":"69","author":"Zhang","year":"2009","journal-title":"Cancer Res."},{"key":"10.1194\/jlr.R046458_bib196","doi-asserted-by":"crossref","first-page":"e22182","DOI":"10.1371\/journal.pone.0022182","article-title":"Autotaxin and LPA receptors represent potential molecular targets for the radiosensitization of murine glioma through effects on tumor vasculature","volume":"6","author":"Schleicher","year":"2011","journal-title":"PLoS ONE."},{"key":"10.1194\/jlr.R046458_bib197","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1111\/j.1476-5381.2010.00828.x","article-title":"A novel, orally active LPA(1) receptor antagonist inhibits lung fibrosis in the mouse bleomycin model","volume":"160","author":"Swaney","year":"2010","journal-title":"Br. J. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib198","doi-asserted-by":"crossref","first-page":"9643","DOI":"10.1073\/pnas.0600979103","article-title":"The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases","volume":"103","author":"Boucharaba","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1194\/jlr.R046458_bib199","doi-asserted-by":"crossref","first-page":"F565","DOI":"10.1152\/ajprenal.00023.2003","article-title":"Selective blockade of lysophosphatidic acid LPA3 receptors reduces murine renal ischemia-reperfusion injury","volume":"285","author":"Okusa","year":"2003","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1194\/jlr.R046458_bib200","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.drudis.2013.01.006","article-title":"Targeting the epithelial cells in fibrosis: a new concept for an old disease","volume":"18","author":"Moll","year":"2013","journal-title":"Drug Discov. Today."},{"key":"10.1194\/jlr.R046458_bib201","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1136\/bmj.318.7181.421","article-title":"Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control study","volume":"318","author":"Hultman","year":"1999","journal-title":"BMJ."},{"issue":"Suppl 2","key":"10.1194\/jlr.R046458_bib202","first-page":"199","article-title":"Risk factors associated with cerebral palsy in newborns","volume":"33","author":"Vukojevi\u0107","year":"2009","journal-title":"Coll. Antropol."},{"key":"10.1194\/jlr.R046458_bib203","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1053\/siny.2001.0047","article-title":"Intraventricular haemorrhage and posthaemorrhagic hydrocephalus: pathogenesis, prevention and future interventions","volume":"6","author":"Whitelaw","year":"2001","journal-title":"Semin. Neonatol."},{"key":"10.1194\/jlr.R046458_bib204","doi-asserted-by":"crossref","first-page":"15444","DOI":"10.1073\/pnas.1106129108","article-title":"Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling","volume":"108","author":"Herr","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1194\/jlr.R046458_bib205","first-page":"126","article-title":"A neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation","volume":"107","author":"Aquilina","year":"2007","journal-title":"J. Neurosurg."},{"key":"10.1194\/jlr.R046458_bib206","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/3-211-30714-1_45","article-title":"Hydrocephalus in a rat model of intraventricular hemorrhage","volume":"96","author":"Lodhia","year":"2006","journal-title":"Acta Neurochir. Suppl."},{"key":"10.1194\/jlr.R046458_bib208","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.schres.2007.07.018","article-title":"Obstetric conditions and risk of first admission with schizophrenia: a Danish national register based study","volume":"97","author":"Byrne","year":"2007","journal-title":"Schizophr. Res."},{"key":"10.1194\/jlr.R046458_bib209","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s10995-006-0142-7","article-title":"Prenatal and birth complications in autism","volume":"11","author":"Brimacombe","year":"2007","journal-title":"Matern. Child Health J."},{"key":"10.1194\/jlr.R046458_bib210","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s11064-005-2611-6","article-title":"Neurochemical changes in LPA1 receptor deficient mice\u2013a putative model of schizophrenia","volume":"30","author":"Roberts","year":"2005","journal-title":"Neurochem. Res."},{"key":"10.1194\/jlr.R046458_bib211","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1017\/S1461145710001240","article-title":"Abnormalities in \u03b1\/\u03b2-CaMKII and related mechanisms suggest synaptic dysfunction in hippocampus of LPA1 receptor knockout mice","volume":"14","author":"Musazzi","year":"2010","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1194\/jlr.R046458_bib212","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1523\/JNEUROSCI.5054-05.2006","article-title":"Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness","volume":"26","author":"Cunningham","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1194\/jlr.R046458_bib213","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1111\/j.1601-183X.2009.00524.x","article-title":"Behavioral phenotype of maLPA1-null mice: increased anxiety-like behavior and spatial memory deficits","volume":"8","author":"Santin","year":"2009","journal-title":"Genes Brain Behav."},{"key":"10.1194\/jlr.R046458_bib214","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.nlm.2010.04.003","article-title":"Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor","volume":"94","author":"Castilla-Ortega","year":"2010","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1194\/jlr.R046458_bib215","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.2174\/092986710791859289","article-title":"Involvement of cytosolic phospholipase A2, calcium independent phospholipase A2 and plasmalogen selective phospholipase A2 in neurodegenerative and neuropsychiatric conditions","volume":"17","author":"Ong","year":"2010","journal-title":"Curr. Med. Chem."},{"key":"10.1194\/jlr.R046458_bib216","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0304-3940(99)00464-4","article-title":"Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve endings in mice","volume":"270","author":"Renb\u00e4ck","year":"1999","journal-title":"Neurosci. Lett."},{"key":"10.1194\/jlr.R046458_bib217","doi-asserted-by":"crossref","first-page":"17608","DOI":"10.1074\/jbc.M111.330183","article-title":"Targeted deletion of LPA5 identifies novel roles for lysophosphatidic acid signaling in development of neuropathic pain","volume":"287","author":"Lin","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib218","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.neuint.2006.09.003","article-title":"LPA-mediated demyelination in ex vivo culture of dorsal root","volume":"50","author":"Fujita","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1194\/jlr.R046458_bib219","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.neuroscience.2007.12.041","article-title":"Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid","volume":"152","author":"Inoue","year":"2008","journal-title":"Neuroscience."},{"key":"10.1194\/jlr.R046458_bib220","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1744-8069-4-6","article-title":"Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain","volume":"4","author":"Inoue","year":"2008","journal-title":"Mol. Pain."},{"key":"10.1194\/jlr.R046458_bib221","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/1744-8069-5-64","article-title":"Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain","volume":"5","author":"Ma","year":"2009","journal-title":"Mol. Pain."},{"key":"10.1194\/jlr.R046458_bib222","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1744-8069-7-33","article-title":"Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain","volume":"7","author":"Kakiuchi","year":"2011","journal-title":"Mol. Pain."},{"key":"10.1194\/jlr.R046458_bib223","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1744-8069-9-29","article-title":"An LPA species (18:1 LPA) plays key roles in the self-amplification of spinal LPA production in the peripheral neuropathic pain model","volume":"9","author":"Ma","year":"2013","journal-title":"Mol. Pain."},{"key":"10.1194\/jlr.R046458_bib224","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/S1388-1981(02)00173-7","article-title":"Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate","volume":"1582","author":"Siess","year":"2002","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.R046458_bib225","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1002\/jcb.20963","article-title":"Lyso\u00adphospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism","volume":"99","author":"Lin","year":"2006","journal-title":"J. Cell. Biochem."},{"key":"10.1194\/jlr.R046458_bib226","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1055\/s-0037-1614867","article-title":"Lysophosphatidic acid activates nuclear factor kappa B and induces proinflammatory gene expression in endothelial cells","volume":"82","author":"Palmetshofer","year":"1999","journal-title":"Thromb. Haemost."},{"key":"10.1194\/jlr.R046458_bib227","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.prostaglandins.2008.05.002","article-title":"Lysophosphatidic acid-induced oxidized low-density lipoprotein uptake is class A scavenger receptor-dependent in macrophages","volume":"87","author":"Chang","year":"2008","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1194\/jlr.R046458_bib228","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1074\/jbc.M505790200","article-title":"Hydrolysis of phosphatidylserine-exposing red blood cells by secretory phospholipase A2 generates lysophosphatidic acid and results in vascular dysfunction","volume":"281","author":"Neidlinger","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib229","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1161\/01.CIR.0000083715.37658.C4","article-title":"Subtype-selective antagonists of lysophosphatidic acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques","volume":"108","author":"Rother","year":"2003","journal-title":"Circulation."},{"key":"10.1194\/jlr.R046458_bib230","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S1474-51510200038-5","article-title":"Platelets and cardiovascular disease","volume":"1","author":"Willoughby","year":"2002","journal-title":"Eur. J. Cardiovasc. Nurs."},{"key":"10.1194\/jlr.R046458_bib231","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1179\/174313208X300369","article-title":"Influence of acetylsalicylate on plasma lysophosphatidic acid level in patients with ischemic cerebral vascular diseases","volume":"30","author":"Li","year":"2008","journal-title":"Neurol. Res."},{"key":"10.1194\/jlr.R046458_bib232","first-page":"E127","article-title":"Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction","volume":"20","author":"van Nieuw Amerongen","year":"2000","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1194\/jlr.R046458_bib233","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1006\/jmcc.2001.1429","article-title":"The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes","volume":"33","author":"Karliner","year":"2001","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1194\/jlr.R046458_bib234","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1634\/stemcells.2007-0098","article-title":"Lysophosphatidic acid protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis","volume":"26","author":"Chen","year":"2008","journal-title":"Stem Cells."},{"key":"10.1194\/jlr.R046458_bib235","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.brainres.2006.05.060","article-title":"EDG receptors as a potential therapeutic target in retinal ischemia-reperfusion injury","volume":"1118","author":"Savitz","year":"2006","journal-title":"Brain Res."},{"key":"10.1194\/jlr.R046458_bib236","doi-asserted-by":"crossref","first-page":"R1174","DOI":"10.1152\/ajpregu.00619.2006","article-title":"Lysophosphatidic acid induces endothelial cell death by modulating the redox environment","volume":"292","author":"Brault","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1194\/jlr.R046458_bib237","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1023\/A:1007542532395","article-title":"Expression of lysophosphatidic acid receptor in rat astrocytes: mitogenic effect and expression of neurotrophic genes","volume":"25","author":"Tabuchi","year":"2000","journal-title":"Neurochem. Res."},{"key":"10.1194\/jlr.R046458_bib238","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1093\/rheumatology\/keq260","article-title":"Lysophosphatidic acid-activated Cl- current activity in human systemic sclerosis skin fibroblasts","volume":"49","author":"Yin","year":"2010","journal-title":"Rheumatology."},{"key":"10.1194\/jlr.R046458_bib239","doi-asserted-by":"crossref","first-page":"168","DOI":"10.7150\/ijms.6.168","article-title":"Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine-1-phosphate in systemic sclerosis","volume":"6","author":"Tokumura","year":"2009","journal-title":"Int. J. Med. Sci."},{"key":"10.1194\/jlr.R046458_bib240","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1164\/rccm.201306-1014OC","article-title":"Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation","volume":"188","author":"Park","year":"2013","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1194\/jlr.R046458_bib241","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1124\/mol.107.038216","article-title":"Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis?","volume":"73","author":"Zhao","year":"2008","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib242","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1002\/art.37991","article-title":"Necessity of lysophosphatidic acid receptor 1 for development of arthritis","volume":"65","author":"Miyabe","year":"2013","journal-title":"Arthritis Rheum."},{"key":"10.1194\/jlr.R046458_bib243","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1093\/hmg\/ddn069","article-title":"A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese","volume":"17","author":"Mototani","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"10.1194\/jlr.R046458_bib244","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1136\/annrheumdis-2012-202832","article-title":"Lysophosphatidic acid receptor inhibition as a new multipronged treatment for rheumatoid arthritis","volume":"73","author":"Orosa","year":"2014","journal-title":"Ann. Rheum. Dis."},{"key":"10.1194\/jlr.R046458_bib245","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/nm1685","article-title":"The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak","volume":"14","author":"Tager","year":"2008","journal-title":"Nat. Med."},{"key":"10.1194\/jlr.R046458_bib246","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1681\/ASN.2007020196","article-title":"LPA1 receptor activation promotes renal interstitial fibrosis","volume":"18","author":"Prad\u00e8re","year":"2007","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1194\/jlr.R046458_bib247","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1096\/fj.12-219378","article-title":"LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation","volume":"27","author":"Sakai","year":"2013","journal-title":"FASEB J."},{"key":"10.1194\/jlr.R046458_bib248","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1165\/rcmb.2013-0070OC","article-title":"Lysophosphatidic acid receptor 2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice","volume":"49","author":"Huang","year":"2013","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1194\/jlr.R046458_bib249","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1006\/bbrc.1998.8983","article-title":"Effects of lysophosphatidic acid on proliferation of stellate cells and hepatocytes in culture","volume":"248","author":"Ikeda","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1194\/jlr.R046458_bib250","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s005350070045","article-title":"Hepatic stellate cells: a target for the treatment of liver fibrosis","volume":"35","author":"Wu","year":"2000","journal-title":"J. Gastroenterol."},{"key":"10.1194\/jlr.R046458_bib252","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.bbrc.2011.04.084","article-title":"Blockade of lysophosphatidic acid receptors LPAR1\/3 ameliorates lung fibrosis induced by irradiation","volume":"409","author":"Gan","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1194\/jlr.R046458_bib253","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.ajpath.2012.06.035","article-title":"Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G\u03b1q-mediated Rho and \u03b1v\u03b26 integrin-dependent activation of TGF-\u03b2","volume":"181","author":"Geng","year":"2012","journal-title":"Am. J. Pathol."},{"key":"10.1194\/jlr.R046458_bib254","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1002\/art.30262","article-title":"Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma","volume":"63","author":"Castelino","year":"2011","journal-title":"Arthritis Rheum."},{"key":"10.1194\/jlr.R046458_bib255","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.bone.2011.12.002","article-title":"The emerging role of lysophosphatidic acid (LPA) in skeletal biology","volume":"50","author":"Blackburn","year":"2012","journal-title":"Bone."},{"key":"10.1194\/jlr.R046458_bib256","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.bbalip.2012.08.001","article-title":"Lysophosphatidic acid: a potential mediator of osteoblast-osteoclast signaling in bone","volume":"1831","author":"Sims","year":"2013","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1194\/jlr.R046458_bib257","doi-asserted-by":"crossref","first-page":"25792","DOI":"10.1074\/jbc.M110.109322","article-title":"Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival","volume":"285","author":"Lapierre","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib258","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.tem.2009.08.003","article-title":"Lysophosphatidic acid (LPA) signaling in vertebrate reproduction","volume":"21","author":"Ye","year":"2010","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1194\/jlr.R046458_bib259","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1095\/biolreprod.107.060293","article-title":"Embryo spacing and implantation timing are differentially regulated by LPA3-mediated lysophosphatidic acid signaling in mice","volume":"77","author":"Hama","year":"2007","journal-title":"Biol. Reprod."},{"key":"10.1194\/jlr.R046458_bib260","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1242\/dev.129.12.2879","article-title":"Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for \u2018on-time\u2019 embryo implantation that directs subsequent development","volume":"129","author":"Song","year":"2002","journal-title":"Development."},{"key":"10.1194\/jlr.R046458_bib261","doi-asserted-by":"crossref","first-page":"8579","DOI":"10.1073\/pnas.0500612102","article-title":"Uterine Wnt\/beta-catenin signaling is required for implantation","volume":"102","author":"Mohamed","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1194\/jlr.R046458_bib262","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1530\/REP-08-0209","article-title":"Lysophosphatic acid modulates prostaglandin secretion in the bovine uterus","volume":"137","author":"Woclawek-Potocka","year":"2009","journal-title":"Reproduction."},{"key":"10.1194\/jlr.R046458_bib263","doi-asserted-by":"crossref","first-page":"986","DOI":"10.3181\/0901-RM-36","article-title":"Lysophosphatidic acid stimulates prostaglandin E2 production in cultured stromal endometrial cells through LPA1 receptor","volume":"234","author":"Woclawek-Potocka","year":"2009","journal-title":"Exp. Biol. Med. (Maywood)."},{"key":"10.1194\/jlr.R046458_bib264","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1095\/biolreprod.108.068783","article-title":"Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling","volume":"79","author":"Ye","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1194\/jlr.R046458_bib265","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1095\/biolreprod63.5.1271","article-title":"Activation of protein kinase Calpha in the lysophosphatidic acid-induced bovine sperm acrosome reaction and phospholipase D1 regulation","volume":"63","author":"Garbi","year":"2000","journal-title":"Biol. Reprod."},{"key":"10.1194\/jlr.R046458_bib266","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.beem.2005.04.002","article-title":"Descriptive epidemiology and health consequences of childhood obesity","volume":"19","author":"Reilly","year":"2005","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"10.1194\/jlr.R046458_bib267","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/ijo.2010.222","article-title":"Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review","volume":"35","author":"Reilly","year":"2011","journal-title":"Int. J. Obes. (Lond)."},{"key":"10.1194\/jlr.R046458_bib268","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.2337\/db08-1770","article-title":"Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation","volume":"58","author":"Isakson","year":"2009","journal-title":"Diabetes."},{"key":"10.1194\/jlr.R046458_bib269","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1172\/JCI806","article-title":"Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growth","volume":"101","author":"Valet","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1194\/jlr.R046458_bib270","doi-asserted-by":"crossref","first-page":"18162","DOI":"10.1074\/jbc.M301158200","article-title":"Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity","volume":"278","author":"Ferry","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib271","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.cbpb.2010.08.010","article-title":"Effects of lysophosphatidic acid on the in vitro proliferation and differentiation of a novel porcine preadipocyte cell line","volume":"157","author":"Nobusue","year":"2010","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1194\/jlr.R046458_bib272","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s00125-004-1660-8","article-title":"Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D\/autotaxin expression","volume":"48","author":"Boucher","year":"2005","journal-title":"Diabetologia."},{"key":"10.1194\/jlr.R046458_bib273","doi-asserted-by":"crossref","first-page":"2664","DOI":"10.1016\/j.yexcr.2010.05.029","article-title":"Non-transactivational, dual pathways for LPA-induced Erk1\/2 activation in primary cultures of brown pre-adipocytes","volume":"316","author":"Holmstr\u00f6m","year":"2010","journal-title":"Exp. Cell Res."},{"key":"10.1194\/jlr.R046458_bib274","doi-asserted-by":"crossref","first-page":"14656","DOI":"10.1074\/jbc.M412585200","article-title":"Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2","volume":"280","author":"Simon","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib275","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/BF03185929","article-title":"Altered food consumption in mice lacking lysophosphatidic acid receptor-1","volume":"65","author":"Dusaulcy","year":"2009","journal-title":"J. Physiol. Biochem."},{"key":"10.1194\/jlr.R046458_bib276","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s00109-007-0269-z","article-title":"Lysophosphatidic acid regulates blood glucose by stimulating myotube and adipocyte glucose uptake","volume":"86","author":"Yea","year":"2008","journal-title":"J. Mol. Med."},{"key":"10.1194\/jlr.R046458_bib277","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1007\/s00125-013-2891-3","article-title":"Lysophosphatidic acid impairs glucose homeostasis and inhibits insulin secretion in high-fat diet obese mice","volume":"56","author":"Rancoule","year":"2013","journal-title":"Diabetologia."},{"key":"10.1194\/jlr.R046458_bib278","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.biochi.2013.04.010","article-title":"Involvement of autotaxin\/lysophosphatidic acid signaling in obesity and impaired glucose homeostasis","volume":"96","author":"Rancoule","year":"2014","journal-title":"Biochimie."},{"key":"10.1194\/jlr.R046458_bib279","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.prostaglandins.2009.02.002","article-title":"Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance","volume":"91","author":"Lin","year":"2010","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1194\/jlr.R046458_bib280","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1476-5381.2010.00815.x","article-title":"Aiming drug discovery at lysophosphatidic acid targets","volume":"161","author":"Tigyi","year":"2010","journal-title":"Br. J. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib281","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1111\/j.1476-5381.2011.01622.x","article-title":"Insights into the pharmacological relevance of lysophospholipid receptors","volume":"165","author":"Mutoh","year":"2012","journal-title":"Br. J. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib282","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s13277-010-0123-8","article-title":"Lysophosphatidic acid (LPA)\u2014a perspective marker in ovarian cancer","volume":"32","author":"Sedl\u00e1kov\u00e1","year":"2010","journal-title":"Tumour Biol."},{"key":"10.1194\/jlr.R046458_bib283","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1042\/bj3090933","article-title":"Lysophospholipids activate ovarian and breast cancer cells","volume":"309","author":"Xu","year":"1995","journal-title":"Biochem. J."},{"key":"10.1194\/jlr.R046458_bib284","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1111\/j.1349-7006.2009.01234.x","article-title":"Expression of autotaxin and acylglycerol kinase in prostate cancer: association with cancer development and progression","volume":"100","author":"Nouh","year":"2009","journal-title":"Cancer Sci."},{"key":"10.1194\/jlr.R046458_bib285","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1476-4598-9-71","article-title":"Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma","volume":"9","author":"Wu","year":"2010","journal-title":"Mol. Cancer."},{"key":"10.1194\/jlr.R046458_bib286","doi-asserted-by":"crossref","first-page":"17492","DOI":"10.1074\/jbc.M601803200","article-title":"Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid","volume":"281","author":"Kishi","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib287","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1016\/j.biocel.2010.09.021","article-title":"Colorectal cancer cells - proliferation, survival and invasion by lysophosphatidic acid","volume":"42","author":"Lee","year":"2010","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1194\/jlr.R046458_bib288","doi-asserted-by":"crossref","first-page":"R640","DOI":"10.1186\/bcr935","article-title":"Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma","volume":"6","author":"Kitayama","year":"2004","journal-title":"Breast Cancer Res."},{"key":"10.1194\/jlr.R046458_bib289","doi-asserted-by":"crossref","first-page":"607","DOI":"10.3858\/emm.2008.40.6.607","article-title":"Lysophosphatidic acid receptor 2 and Gi\/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells","volume":"40","author":"Jeong","year":"2008","journal-title":"Exp. Mol. Med."},{"key":"10.1194\/jlr.R046458_bib290","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.ygyno.2008.09.019","article-title":"LPA receptor 2 mediates LPA-induced endometrial cancer invasion","volume":"112","author":"Hope","year":"2009","journal-title":"Gynecol. Oncol."},{"key":"10.1194\/jlr.R046458_bib291","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3325\/cmj.2008.2.175","article-title":"Inhibition of lysophosphatidic acid receptor-2 expression by RNA interference decreases lysophosphatidic acid-induced urokinase plasminogen activator activation, cell invasion, and migration in ovarian cancer SKOV-3 cells","volume":"49","author":"Wang","year":"2008","journal-title":"Croat. Med. J."},{"key":"10.1194\/jlr.R046458_bib292","doi-asserted-by":"crossref","first-page":"C2","DOI":"10.1152\/ajpcell.00610.2004","article-title":"LPA2 receptor mediates mitogenic signals in human colon cancer cells","volume":"289","author":"Yun","year":"2005","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1194\/jlr.R046458_bib293","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1038\/sj.onc.1206986","article-title":"Induction of protein growth factor systems in the ovaries of transgenic mice overexpressing human type 2 lysophosphatidic acid G protein-coupled receptor (LPA2)","volume":"23","author":"Huang","year":"2004","journal-title":"Oncogene."},{"key":"10.1194\/jlr.R046458_bib294","doi-asserted-by":"crossref","first-page":"6569","DOI":"10.1158\/0008-5472.CAN-08-0411","article-title":"Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphin\u00adgosine kinase 1 to promote gastric cancer cell motility and invasion","volume":"68","author":"Shida","year":"2008","journal-title":"Cancer Res."},{"key":"10.1194\/jlr.R046458_bib295","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/pros.20879","article-title":"Gene expression profiles of lysophosphatidic acid-related molecules in the prostate: relevance to prostate cancer and benign hyperplasia","volume":"69","author":"Zeng","year":"2009","journal-title":"Prostate."},{"key":"10.1194\/jlr.R046458_bib296","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1093\/jnci\/djn378","article-title":"Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells","volume":"100","author":"Yu","year":"2008","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1194\/jlr.R046458_bib297","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.bone.2005.12.013","article-title":"Lysophosphatidic acid induces chemotaxis in MC3T3-E1 osteoblastic cells","volume":"39","author":"Masiello","year":"2006","journal-title":"Bone."},{"key":"10.1194\/jlr.R046458_bib298","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1158\/1541-7786.MCR-08-0578","article-title":"Beta-arrestin\/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells","volume":"7","author":"Li","year":"2009","journal-title":"Mol. Cancer Res."},{"key":"10.1194\/jlr.R046458_bib299","doi-asserted-by":"crossref","first-page":"6595","DOI":"10.1074\/jbc.M308133200","article-title":"Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1","volume":"279","author":"Yamada","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1194\/jlr.R046458_bib300","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1159\/000319875","article-title":"Mutations of lysophosphatidic acid receptor genes in human osteosarcoma cells","volume":"77","author":"Okabe","year":"2010","journal-title":"Pathobiology."},{"key":"10.1194\/jlr.R046458_bib301","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.mrfmmm.2008.10.005","article-title":"Frequent mutations of lysophosphatidic acid receptor-1 gene in rat liver tumors","volume":"660","author":"Obo","year":"2009","journal-title":"Mutat. Res."},{"key":"10.1194\/jlr.R046458_bib302","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s00432-008-0441-z","article-title":"Lysophosphatidic acid signaling through LPA receptor subtype 1 induces colony scattering of gastrointestinal cancer cells","volume":"135","author":"Shin","year":"2009","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"10.1194\/jlr.R046458_bib303","doi-asserted-by":"crossref","first-page":"e9741","DOI":"10.1371\/journal.pone.0009741","article-title":"Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts","volume":"5","author":"David","year":"2010","journal-title":"PLoS ONE."},{"key":"10.1194\/jlr.R046458_bib304","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1023\/A:1020950420196","article-title":"Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells","volume":"19","author":"Yang","year":"2002","journal-title":"Clin. Exp. Metastasis."},{"key":"10.1194\/jlr.R046458_bib305","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1165\/ajrcmb.21.2.3667","article-title":"Autotaxin expression in non-small-cell lung cancer","volume":"21","author":"Yang","year":"1999","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1194\/jlr.R046458_bib306","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/ijc.20022","article-title":"Expression, regulation and function of autotaxin in thyroid carcinomas","volume":"109","author":"Kehlen","year":"2004","journal-title":"Int. J. Cancer."},{"key":"10.1194\/jlr.R046458_bib307","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s12029-010-9186-4","article-title":"Immunohistochemical detection of autotaxin (ATX)\/lysophospholipase D (lysoPLD) in submucosal invasive colorectal cancer","volume":"42","author":"Kazama","year":"2011","journal-title":"J. Gastrointest. Cancer."},{"key":"10.1194\/jlr.R046458_bib308","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/onc.2008.442","article-title":"Autotaxin protects MCF-7 breast cancer and MDA-MB-435 melanoma cells against Taxol-induced apoptosis","volume":"28","author":"Samadi","year":"2009","journal-title":"Oncogene."},{"key":"10.1194\/jlr.R046458_bib309","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s10555-011-9319-7","article-title":"Autotaxin and LPA receptor signaling in cancer","volume":"30","author":"Houben","year":"2011","journal-title":"Cancer Metastasis Rev."},{"key":"10.1194\/jlr.R046458_bib310","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.ccr.2009.05.003","article-title":"Mammary tumorigenesis through LPA receptor signaling","volume":"15","author":"Jonkers","year":"2009","journal-title":"Cancer Cell."},{"key":"10.1194\/jlr.R046458_bib311","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/boc.201300011","article-title":"Lysophosphatidic acid (LPA) signalling in cell migration and cancer invasion: a focussed review and analysis of LPA receptor gene expression on the basis of more than 1700 cancer microarrays","volume":"105","author":"Willier","year":"2013","journal-title":"Biol. Cell."},{"key":"10.1194\/jlr.R046458_bib312","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.cellsig.2008.06.008","article-title":"Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA(1\/3), COX-2, and NF-kappaB activation- and EGFR transactivation-dependent mechanisms","volume":"20","author":"Lin","year":"2008","journal-title":"Cell. Signal."},{"key":"10.1194\/jlr.R046458_bib313","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1158\/0008-5472.CAN-11-3406","article-title":"Anti-VEGF\/VEGFR therapy for cancer: reassessing the target","volume":"72","author":"Sitohy","year":"2012","journal-title":"Cancer Res."},{"key":"10.1194\/jlr.R046458_bib314","doi-asserted-by":"crossref","first-page":"280","DOI":"10.3858\/emm.2010.42.4.027","article-title":"Ovarian cancer-derived lysophosphatidic acid stimulates secretion of VEGF and stromal cell-derived factor-1 alpha from human mesenchymal stem cells","volume":"42","author":"Jeon","year":"2010","journal-title":"Exp. Mol. Med."},{"key":"10.1194\/jlr.R046458_bib315","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ygyno.2011.06.006","article-title":"The NF-\u03baB pathway mediates lysophosphatidic acid (LPA)-induced VEGF signaling and cell invasion in epithelial ovarian cancer (EOC)","volume":"123","author":"Dutta","year":"2011","journal-title":"Gynecol. Oncol."},{"key":"10.1194\/jlr.R046458_bib316","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1111\/j.1349-7006.2012.02246.x","article-title":"Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo","volume":"103","author":"Komachi","year":"2012","journal-title":"Cancer Sci."},{"key":"10.1194\/jlr.R046458_bib317","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1093\/jnci\/djs319","article-title":"Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer","volume":"104","author":"Marshall","year":"2012","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1194\/jlr.R046458_bib318","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.bmcl.2007.12.024","article-title":"Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents","volume":"18","author":"Beck","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1194\/jlr.R046458_bib319","series-title":"Liberation Ecologies: Environment, development, socialmovements","first-page":"1","article-title":"MRI diagnostic accuracy in Creutzfeldt-Jakob disease: results of a multicenter study","author":"Mirendil","year":"2013"},{"key":"10.1194\/jlr.R046458_bib320","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1124\/mol.54.5.881","article-title":"Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization","volume":"54","author":"An","year":"1998","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib322","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1038\/aps.2010.135","article-title":"Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors","volume":"31","author":"Im","year":"2010","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1194\/jlr.R046458_bib323","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1006\/abbi.1994.1249","article-title":"Biochemical characterization of the interaction of lipid phosphoric acids with human platelets: comparison with platelet activating factor","volume":"311","author":"Sugiura","year":"1994","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1194\/jlr.R046458_bib324","doi-asserted-by":"crossref","first-page":"4919","DOI":"10.1021\/jm049609r","article-title":"Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin","volume":"48","author":"Durgam","year":"2005","journal-title":"J. Med. Chem."},{"key":"10.1194\/jlr.R046458_bib325","doi-asserted-by":"crossref","first-page":"635","DOI":"10.2478\/v10181-012-0100-9","article-title":"Participation of analogues of lysophosphatidic acid (LPA): oleoyl-sn-glycero-3-phosphate (L-alpha-LPA) and 1-oleoyl-2-O-methyl-rac-glycerophosphothionate (OMPT) in uterine smooth muscle contractility of the pregnant pigs","volume":"15","author":"Markiewicz","year":"2012","journal-title":"Pol. J. Vet. Sci."},{"key":"10.1194\/jlr.R046458_bib326","doi-asserted-by":"crossref","first-page":"2834","DOI":"10.1002\/anie.200454065","article-title":"Identifying specific conformations by using a carbohydrate scaffold: discovery of subtype-selective LPA-receptor agonists and an antagonist","volume":"43","author":"Tamaruya","year":"2004","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1194\/jlr.R046458_bib327","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1124\/mol.63.5.1032","article-title":"Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors","volume":"63","author":"Virag","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib328","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/cmdc.200500042","article-title":"Phosphorothioate analogues of alkyl lysophosphatidic acid as LPA3 receptor-selective agonists","volume":"1","author":"Qian","year":"2006","journal-title":"ChemMedChem."},{"key":"10.1194\/jlr.R046458_bib329","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1016\/j.bmcl.2013.01.002","article-title":"Phosphorothioate analogs of sn-2 radyl lysophosphatidic acid (LPA): metabolically stabilized LPA receptor agonists","volume":"23","author":"Jiang","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1194\/jlr.R046458_bib330","doi-asserted-by":"crossref","first-page":"e70941","DOI":"10.1371\/journal.pone.0070941","article-title":"A metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritis","volume":"8","author":"Nikitopoulou","year":"2013","journal-title":"PLoS ONE."},{"key":"10.1194\/jlr.R046458_bib331","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1124\/mol.64.4.994","article-title":"Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors","volume":"64","author":"Ohta","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib333","series-title":"In Lysophospholipid Receptors: Signaling and Biochemistry.","first-page":"681","article-title":"LPA receptor subtypes LPA1 and LPA2 as potential drug targets.","author":"Bain","year":"2013"},{"key":"10.1194\/jlr.R046458_bib334","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.3892\/ijo.2011.1309","article-title":"Targeting lysophosphatidic acid receptor type 1 with Debio 0719 inhibits spontaneous metastasis dissemination of breast cancer cells independently of cell proliferation and angiogenesis","volume":"40","author":"David","year":"2012","journal-title":"Int. J. Oncol."},{"key":"10.1194\/jlr.R046458_bib335","doi-asserted-by":"crossref","first-page":"6207","DOI":"10.1016\/j.bmc.2008.04.035","article-title":"Identification of non-lipid LPA3 antagonists by virtual screening","volume":"16","author":"Fells","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"10.1194\/jlr.R046458_bib336","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1124\/jpet.110.175901","article-title":"Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist","volume":"336","author":"Swaney","year":"2011","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1194\/jlr.R046458_bib338","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/S0026-895X(24)12305-X","article-title":"Short-chain phosphatidates are subtype-selective antagonists of lysophosphatidic acid receptors","volume":"60","author":"Fischer","year":"2001","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib339","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2210-12-7","article-title":"Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA1 receptor signalling in rat brain cryosections without affecting global LPA degradation","volume":"12","author":"Aaltonen","year":"2012","journal-title":"BMC Pharmacol."},{"key":"10.1194\/jlr.R046458_bib340","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0003-9861(02)00038-3","article-title":"2-Arachidonoyl-sn-glycero-3-phosphate, an arachidonic acid-containing lysophosphatidic acid: occurrence and rapid enzymatic conversion to 2-arachidonoyl-sn-glycerol, a cannabinoid receptor ligand, in rat brain","volume":"402","author":"Nakane","year":"2002","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1194\/jlr.R046458_bib341","doi-asserted-by":"crossref","first-page":"e41456","DOI":"10.1371\/journal.pone.0041456","article-title":"Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes","volume":"7","author":"Barber","year":"2012","journal-title":"PLoS ONE."},{"key":"10.1194\/jlr.R046458_bib342","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0009-9120(02)00327-2","article-title":"An enzymatic assay for lysophosphatidylcholine concentration in human serum and plasma","volume":"35","author":"Kishimoto","year":"2002","journal-title":"Clin. Biochem."},{"key":"10.1194\/jlr.R046458_bib343","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1007\/s10096-011-1505-6","article-title":"Clinical significance of enzymatic lysophosphatidylcholine (LPC) assay data in patients with sepsis","volume":"31","author":"Cho","year":"2012","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1194\/jlr.R046458_bib344","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1111\/j.1471-4159.2004.02933.x","article-title":"Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources","volume":"92","author":"Sato","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1194\/jlr.R046458_bib345","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1194\/jlr.M200242-JLR200","article-title":"Lysophosphatidic acid, a growth factor-like lipid, in the saliva","volume":"43","author":"Sugiura","year":"2002","journal-title":"J. Lipid Res."},{"key":"10.1194\/jlr.R046458_bib346","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.lfs.2007.08.013","article-title":"Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity","volume":"81","author":"Watanabe","year":"2007","journal-title":"Life Sci."},{"key":"10.1194\/jlr.R046458_bib207","unstructured":".Deleted in proof."},{"key":"10.1194\/jlr.R046458_bib251","unstructured":".Deleted in proof."},{"key":"10.1194\/jlr.R046458_bib321","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/S0026-895X(25)09327-7","article-title":"N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors","volume":"50","author":"Liliom","year":"1996","journal-title":"Mol. Pharmacol."},{"key":"10.1194\/jlr.R046458_bib332","doi-asserted-by":"crossref","first-page":"4323","DOI":"10.1016\/j.bmcl.2012.05.012","article-title":"Synthesis and biological evaluation of optically active Ki16425","volume":"22","author":"Sato","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1194\/jlr.R046458_bib337","unstructured":".Deleted in proof."}],"container-title":["Journal of Lipid Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022227520352299?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022227520352299?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1194\/jlr.R046458","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T03:01:53Z","timestamp":1746154913000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022227520352299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":346,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0022227520352299"],"URL":"https:\/\/doi.org\/10.1194\/jlr.r046458","relation":{},"ISSN":["0022-2275"],"issn-type":[{"value":"0022-2275","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}