{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T04:26:07Z","timestamp":1759638367513},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,1,12]],"date-time":"2006-01-12T00:00:00Z","timestamp":1137024000000},"content-version":"vor","delay-in-days":468,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:p><jats:bold>A<jats:sc>bstract<\/jats:sc>: <\/jats:bold>  <jats:italic>Boophilus microplus<\/jats:italic> is an important vector of bovine disease agents having a major economic impact on cattle production in many tropical and subtropical countries. Components of tick saliva that enable ticks to feed may also facilitate establishment of tick\u2010borne pathogens in the vertebrate host. It has been suggested that acquired resistance against molecules in tick saliva could inhibit parasite transmission, and there is increasing evidence to support this hypothesis. The effect of immune resistance to <jats:italic>B. microplus<\/jats:italic> on the incidence of tick\u2010transmitted pathogens was the focus of this experiment. Groups of four dairy cows were injected with antigen extracts of tick salivary glands, midgut, adjuvant only, or PBS, prior to a grazing period in a pasture in Thailand where ticks are abundant and babesiosis is enzootic. These animals were then observed for evidence of babesiosis throughout the rainy season. A reduction in the incidence of clinical babesiosis was observed among cattle immunized with salivary gland preparations compared to nonimmunized controls (<jats:styled-content><jats:italic>P<\/jats:italic> &lt; 0.05<\/jats:styled-content>). Immunization with midgut or adjuvant only both resulted in a slight reduction in observed disease compared to the same negative control group. <jats:italic>B. bigemina<\/jats:italic> was detected in fewer ticks (24.43%) collected from salivary gland\u2010immunized cattle than those collected from the remaining groups (\u226544.57%). These results indicated that immunization with salivary gland antigens could affect pathogen transmission and appears promising for control of tick\u2010borne diseases of cattle.<\/jats:p>","DOI":"10.1196\/annals.1307.048","type":"journal-article","created":{"date-parts":[[2004,12,16]],"date-time":"2004-12-16T23:57:42Z","timestamp":1103241462000},"page":"312-318","source":"Crossref","is-referenced-by-count":8,"title":["Reduced Incidence of <i>Babesia bigemina<\/i> Infection in Cattle Immunized against the Cattle Tick, <i>Boophilus microplus<\/i>"],"prefix":"10.1111","volume":"1026","author":[{"given":"SATHAPORN","family":"JITTAPALAPONG","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WEERAPHOL","family":"JANSAWAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"OMAR O.","family":"BARRIGA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ROGER W.","family":"STICH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,12]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(95)00071-9"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(94)00733-S"},{"key":"e_1_2_6_4_2","unstructured":"Galun R. 1975. Research into alternative arthropod control measures against livestock pests (part 1).InWorkshop on the Ecology and Control of External Parasites of Economic Importance on Bovines in Latin America pp. 155\u2010161. Centro Internacional de Agricultura Tropical (CIAT). Columbia."},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000001487"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(96)01082-5"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(89)90177-X"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4439(00)00026-0"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1979.28.876"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","unstructured":"Nazario S. S. Das A.M. de Silvaet al.1998. Prevention ofBorrelia burgdorferitransmission in guinea pigs by tick immunity. Am. J. Trop. Med. 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Commercialization of the recombinant vaccine Gavac againstBoophilus microplusin Columbia.InRecombinant Vaccines for the Control of Cattle Tick pp. 196\u2010199. Elfos Scientiae. La Habana Cuba."},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(93)90008-B"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.60.509"},{"key":"e_1_2_6_18_2","doi-asserted-by":"crossref","unstructured":"Suarez C.E. C.H. Palmer D.P. Jasmeret al.1991. Characterization of the gene encoding a 60\u2010kilodaltonBabesia bovismerozoite protein with conserved and surface exposed epitopes. Mol. Biochem. Parasitol.46:45\u201352.","DOI":"10.1016\/0166-6851(91)90197-E"},{"key":"e_1_2_6_19_2","doi-asserted-by":"crossref","unstructured":"Tanayuthawongese C. K. Saengsombul W. Sukhumsirichatet al.1999. Detection of bovine hemoparasite infection using multiplex polymerase chain reaction. Sci. 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