{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:47:02Z","timestamp":1761058022914},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,1,12]],"date-time":"2006-01-12T00:00:00Z","timestamp":1137024000000},"content-version":"vor","delay-in-days":590,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:p><jats:bold>A<jats:sc>bstract<\/jats:sc>: <\/jats:bold> Adolescent rats have been reported to be less sensitive than adults to many acute ethanol effects, including ethanol\u2010induced sedation and motor impairment, but conversely more sensitive to ethanol\u2010induced disruptions in spatial memory in a Morris water maze (Markwiese <jats:italic>et al.<\/jats:italic>, 1998). The present study examined adolescent and adult rats trained for 6 days under spatial or nonspatial versions of a presumably less stressful sand box maze. Moderately food\u2010deprived animals were given 0, 0.5, or 1.5 g\/kg ethanol intraperitoneally 30 min before training each day, but were tested without ethanol or reinforcer on test day. Spatial acquisition was impaired by 1.5 g\/kg in adults but not adolescents, with no ethanol impairment on the nonspatial task at either age. These results are opposite the ontogenetic profile reported by Markwiese <jats:italic>et al.<\/jats:italic>, (1998) and may reflect differential activation of prefrontal cortex or other stress\u2010sensitive forebrain regions by the two tasks across age.<\/jats:p>","DOI":"10.1196\/annals.1308.060","type":"journal-article","created":{"date-parts":[[2004,7,13]],"date-time":"2004-07-13T02:59:39Z","timestamp":1089687579000},"page":"441-444","source":"Crossref","is-referenced-by-count":38,"title":["The Effects of Ethanol on Spatial and Nonspatial Memory in Adolescent and Adult Rats Studied Using an Appetitive Paradigm"],"prefix":"10.1111","volume":"1021","author":[{"given":"P","family":"RAJENDRAN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L P","family":"SPEAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,12]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"Johnston L.D. P.M. O'Malley & J.G. Bachman. 2001. National Survey Results on Drug Use from the Monitoring the Future Study 1975\u20102000. Vol. I: Secondary School Students (NIH Publication No. 01\u20104924). National Institute on Drug Abuse. Bethesda MD."},{"key":"e_1_2_6_3_2","unstructured":"White A.M. et al.2001. Differences in EtOH\u2010induced motor impairments and EtOH metabolism in adolescent and adult rats. Alcohol. Clin. Exp. Res.25(Suppl.): 109A."},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2002.tb02449.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.1998.tb04310.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1111\/j.1530-0277.1996.tb01133.x","article-title":"Differential effects of ethanol in adolescent and adult rats","volume":"20","author":"Little P.J.","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.1998.tb03668.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-8329(99)00021-X"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9384(97)00366-1"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","unstructured":"Hanson G.R. & D.C. Riccio. 2001. The sand maze: an appetitive alternative to the Morris water maze. Presented at the Midwestern Psychological Association Poster Session May 2001.","DOI":"10.1037\/e413802005-457"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1196%2Fannals.1308.060","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1196\/annals.1308.060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T07:34:43Z","timestamp":1695627283000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1196\/annals.1308.060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["10.1196\/annals.1308.060"],"URL":"https:\/\/doi.org\/10.1196\/annals.1308.060","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}