{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:20:40Z","timestamp":1770337240802,"version":"3.49.0"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,10,31]],"date-time":"2006-10-31T00:00:00Z","timestamp":1162252800000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p><jats:bold><jats:sc>Abstract:\u2002<\/jats:sc><\/jats:bold>  <jats:bold>Researchers have long appreciated the role of climate in vector\u2010borne diseases, including the resurgence of boutonneuse fever (BF). Portugal usually is classified as having temperate Mediterranean climate. In this new century, in analyzing the data from the Meteorology Institute, this pattern has changed and an accentuated variability in climate is being observed. BF (<jats:italic>febre escaro nodular<\/jats:italic>) is endemic and high season is from late spring and summer. The brown dog tick <jats:italic>Rhipicephalus sanguineus.<\/jats:italic> is the vector and reservoir of <jats:italic>Rickettsia conorii complex<\/jats:italic> strains: <jats:italic>R. conorii<\/jats:italic> Malish and Israeli spotted fever strain. To assess the influence of climate change in BF seasonality our aim was to compare the human sera samples received at CEVDI\u2013INSA for laboratory diagnosis of MSF for 5 months per year from October to February, (\u201coff\u2010season\u201d) from 2000 to 2005. Of 1,299 sera samples in persons with suspected clinical diagnosis of MSF, 45 (3.4%) were considered positive cases and the number of positive cases has doubled in the last 2 years. BF epidemiology clearly appears to be associated with climate change, especially with low precipitation values. Physicians should be aware of increasing off\u2010season BF cases.<\/jats:bold> <\/jats:p>","DOI":"10.1196\/annals.1374.029","type":"journal-article","created":{"date-parts":[[2006,11,18]],"date-time":"2006-11-18T02:13:56Z","timestamp":1163816036000},"page":"162-169","source":"Crossref","is-referenced-by-count":17,"title":["Boutonneuse Fever and Climate Variability"],"prefix":"10.1111","volume":"1078","author":[{"given":"RITA","family":"De SOUSA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TERESA","family":"LUZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PAULO","family":"PARREIRA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARGARIDA","family":"SANTOS\u2010SILVA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FATIMA","family":"BACELLAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,31]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"crossref","unstructured":"Epstein D.1996.The climate of change: omens for the future. Perspectives in Health. PAHO Today.","DOI":"10.1037\/e363022004-002"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcped.2003.12.020"},{"key":"e_1_2_5_4_2","volume-title":"Potenciais Impactos De Altera\u00e7\u00f5es Clim\u00e1ticas Na Sa\u00fade Humana e Implica\u00e7\u00f5es para o Turismo em Portugal","author":"Calheiros J.","year":"2004"},{"key":"e_1_2_5_5_2","first-page":"429","article-title":"Epidemiologic features of Mediterranean spotted fever in Portugal","volume":"16","author":"De Sousa R.","year":"2003","journal-title":"Acta Med. Port."},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023391212354"},{"key":"e_1_2_5_7_2","first-page":"143","article-title":"Ciclos biol\u00f3gicos de ixod\u00eddeos (Ixodoidea: Ixodidae) em condi\u00e7\u00f5es de laborat\u00f3rio","volume":"527","author":"Silva M.","year":"1998","journal-title":"Rev. Port. Ci\u00ean. 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