{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:32:07Z","timestamp":1791340327915,"version":"4.3.1"},"reference-count":122,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,10,31]],"date-time":"2006-10-31T00:00:00Z","timestamp":1162252800000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:sc>Abstract:\u2002<\/jats:sc>\n                    <\/jats:bold>\n                    <jats:bold>\n                      The agent that causes tick\u2010borne fever (TBF) in sheep was first described in 1940, 8 years after the disease was first recognized in Scotland. The same agent was soon shown to cause TBF in sheep and pasture fever in cattle in other parts of the UK, Scandinavia, and other parts of Europe. After the initial use of the name\n                      <jats:italic>Rickettsia phagocytophila<\/jats:italic>\n                      , the organism was given the name\n                      <jats:italic>Cytoecetes phagocytophila<\/jats:italic>\n                      to reflect its association with granulocytes and its morphological similarity with\n                      <jats:italic>Cytoecetes microti<\/jats:italic>\n                      . This name continued to be used by workers in the UK until the recent reclassification of the granulocytic ehrlichiae affecting ruminants, horses, and humans as variants of the same species,\n                      <jats:italic>Anaplasma phagocytophilum<\/jats:italic>\n                      . TBF and pasture fever are characterized by high fever, recurrent bacteremia, neutropenia, lymphocytopenia, thrombocytopenia, and general immunosuppression, resulting in more severe secondary infections such as tick pyemia, pneumonic pasteurellosis, listeriosis, and enterotoxemia. During the peak period of bacteremia as many as 90% of granulocytes may be infected. The agent is transmitted transtadially by the hard tick\n                      <jats:italic>Ixodes ricinus<\/jats:italic>\n                      , and possibly other ticks. After patent bacteremia, sheep, goats, and cattle become persistently infected \u201ccarriers,\u201d perhaps playing an important role in the maintenance of infection, in the flock\/herd. Little is known about how efficiently ticks acquire and maintain infection in ruminant populations or whether \u201ccarrier\u201d domestic ruminants play an important role as reservoirs of infection, but deer, other free\u2010living ruminants, and wild rodents are also potential sources of infection. During the late 1990s serological evidence of infection of humans was demonstrated in several European countries, creating a renewed interest and increased awareness of the zoonotic potential of TBF variants. More recently, a few cases of human granulocytic anaplasmosis (HGA) have been reported in some European countries, but it remains to be established whether the variants causing HGA in Europe are genetically and biologically different from those causing TBF in ruminants. TBF is readily diagnosed by demonstrating intracytoplasmic inclusions in peripheral blood granulocytes or monocytes of febrile animals or by detecting specific DNA by polymerase chain reaction (PCR), and TBF variants of\n                      <jats:italic>A. phagocytophilum<\/jats:italic>\n                      can be cultivated in tick cell lines, but the differentiation of TBF variants from HGA variants awaits further investigations.\n                    <\/jats:bold>\n                  <\/jats:p>","DOI":"10.1196\/annals.1374.084","type":"journal-article","created":{"date-parts":[[2006,11,17]],"date-time":"2006-11-17T21:13:56Z","timestamp":1163798036000},"page":"446-460","source":"Crossref","is-referenced-by-count":127,"title":["<i>Anaplasma phagocytophilum<\/i>\n                    in Ruminants in Europe"],"prefix":"10.1111","volume":"1078","author":[{"given":"ZERAI","family":"WOLDEHIWET","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,10,31]]},"reference":[{"key":"e_1_2_10_2_2","first-page":"233","volume-title":"Rickettsial and Chlamydial Diseases of Domestic Animals","author":"Woldehiwet Z.","year":"1993"},{"key":"e_1_2_10_3_2","unstructured":"Gordon W.S. A.Brownlee&D.R.Wilson.1940.Studies on louping ill tick\u2010borne fever and scrapie.Proceedings of the Third International Congress on Microbiology New York pp.362."},{"key":"e_1_2_10_4_2","first-page":"276","article-title":"Preliminary studies in tick transmission of louping ill. II. A study of the reaction of sheep to tick infestation","volume":"88","author":"MacLeod J.","year":"1932","journal-title":"Vet. J."},{"key":"e_1_2_10_5_2","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0007-1935(17)53027-4","article-title":"The recognition of tick\u2010borne fever as a disease of cattle","volume":"106","author":"Hudson J. R.","year":"1950","journal-title":"Br. Vet. J."},{"key":"e_1_2_10_6_2","first-page":"162","article-title":"Tick\u2010borne fever in Ireland","volume":"24","author":"Collins J.D.","year":"1970","journal-title":"Ir. Vet. J."},{"key":"e_1_2_10_7_2","unstructured":"Thorshaug K.1940.Cited by S. Stuen 2003.Anaplasma phagocytophilum(formerlyEhrlichia phagocytophila) infection in sheep and wild ruminants in Norway: a study on clinical manifestation distribution and persistence.Doctor Philosophiae thesis Norwegian College of Veterinary Medicine Oslo ."},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1967.tb01311.x"},{"key":"e_1_2_10_9_2","first-page":"1519","article-title":"Tick\u2010borne fever in cattle in the Netherlands","volume":"89","author":"Bool P.H.","year":"1964","journal-title":"Tijdschr. Diergeneeskd."},{"key":"e_1_2_10_10_2","first-page":"364","article-title":"Zwei neue infektiose Blutkrankheiten des Rindes in Osterreich","volume":"60","author":"Hinaidy H. K.","year":"1973","journal-title":"Wien. Tierarztl. Monatsschrift."},{"key":"e_1_2_10_11_2","first-page":"343","article-title":"Ehrlichia phagocytophila als Erreger des \u201cWeidefieber\u201ds im Berner Oberland","volume":"129","author":"Pfister K.","year":"1987","journal-title":"Schweizer Archiv fur Tierheilkunde"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.124.24.636"},{"key":"e_1_2_10_13_2","first-page":"181","article-title":"Ehrlichiosis bovine (fievre des patures): une observation en France","volume":"24","author":"Argente G.","year":"1992","journal-title":"Point Veterinaire"},{"key":"e_1_2_10_14_2","first-page":"v\u2013vi","article-title":"Studies on tick\u2010borne fever","author":"Foggie A.","year":"1949","journal-title":"J. Gen. Microbiol."},{"key":"e_1_2_10_15_2","first-page":"51","article-title":"Studies on tick pyemia and tick\u2010borne fever","volume":"6","author":"Foggie A.","year":"1962","journal-title":"Symp. Zool. Soc. Lond."},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000025774"},{"key":"e_1_2_10_17_2","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1099\/00207713-51-6-2145","article-title":"Reorganisation of the genera of the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new combinations and designations of Ehrlichia equi and \u2018HGE agent\u2019 as subjective synonyms of Ehrlichia phagocytophila","volume":"51","author":"Dumler J.S.","year":"2001","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.32.3.589-595.1994"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1086\/514683"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)92502-3"},{"key":"e_1_2_10_21_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268898001514"},{"key":"e_1_2_10_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.122.3.66"},{"key":"e_1_2_10_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.85.21.585"},{"key":"e_1_2_10_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1935(17)41151-1"},{"key":"e_1_2_10_25_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268899003684"},{"key":"e_1_2_10_26_2","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-37.3.614"},{"key":"e_1_2_10_27_2","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-37.1.201"},{"key":"e_1_2_10_28_2","first-page":"641","article-title":"Infection with Anaplasma phagocytophila in cervids from Slovenia: evidence of two genotypic lineages","volume":"114","author":"Petrovec M.","year":"2002","journal-title":"Wien. Klin. Wochenschrift."},{"key":"e_1_2_10_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.3.892-897.2002"},{"key":"e_1_2_10_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.5.2285-2286.2004"},{"key":"e_1_2_10_31_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000022514"},{"key":"e_1_2_10_32_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2915.1998.00133.x"},{"key":"e_1_2_10_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.3.1002-1007.2000"},{"key":"e_1_2_10_34_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0901.020169"},{"key":"e_1_2_10_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1999.tb03249.x"},{"key":"e_1_2_10_36_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.140.9.222"},{"key":"e_1_2_10_37_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.36.12.3460-3462.1998"},{"key":"e_1_2_10_38_2","first-page":"727","article-title":"Canine granulocytic ehrlichiosis in the UK","volume":"148","author":"Shaw S.","year":"2001","journal-title":"Vet. Rec."},{"key":"e_1_2_10_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1438-4221(02)80019-4"},{"key":"e_1_2_10_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2004.02.008"},{"key":"e_1_2_10_41_2","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1128\/JCM.36.7.2035-2037.1998","article-title":"Identification of a granulocytic Ehrlichia strain isolated from a horse in Switzerland and comparison with other rickettsiae of the Ehrlichia phagocytophila genogroup","volume":"36","author":"Pusterla N.","year":"1998","journal-title":"J. Clin. Microbiol."},{"key":"e_1_2_10_42_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1999.tb03853.x"},{"key":"e_1_2_10_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5877(01)00187-8"},{"key":"e_1_2_10_44_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.150.25.787"},{"key":"e_1_2_10_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91544-3"},{"key":"e_1_2_10_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.35.12.3244-3247.1997"},{"key":"e_1_2_10_47_2","doi-asserted-by":"publisher","DOI":"10.1080\/003655498750003582"},{"key":"e_1_2_10_48_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01691120"},{"key":"e_1_2_10_49_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365549950161880"},{"key":"e_1_2_10_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.35.6.1556-1559.1997"},{"key":"e_1_2_10_51_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199904153401517"},{"key":"e_1_2_10_52_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0604.000425"},{"issue":"1","key":"e_1_2_10_53_2","first-page":"194","article-title":"First description of the human granulocytic ehrlichiosis in Croatia","volume":"6","author":"Misic\u2010Majerus L.J.","year":"2000","journal-title":"Clin. Microbiol. Infect."},{"key":"e_1_2_10_54_2","first-page":"805","article-title":"Human granulocytic ehrlichiosis\u2014a case in Scandinavia","volume":"33","author":"Karlsson U.","year":"2001","journal-title":"Scand. J. Infect. Dis."},{"key":"e_1_2_10_55_2","first-page":"805","article-title":"Human granulocytic ehrlichiosis in Norway","volume":"121","author":"Kristensen B.E.","year":"2001","journal-title":"Tisskr. Nor. Laegeforen."},{"key":"e_1_2_10_56_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100960100464"},{"key":"e_1_2_10_57_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0691.2002.00557.x"},{"issue":"37","key":"e_1_2_10_58_2","first-page":"27","article-title":"Human granulocytic ehrlichiosis in Europe","volume":"293","author":"Strle F.","year":"2004","journal-title":"Int. J. Med. Microbiol."},{"key":"e_1_2_10_59_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000019442"},{"key":"e_1_2_10_60_2","first-page":"29","article-title":"Ticks and disease in domestic stock in Great Britain","volume":"6","author":"MacLeod J.","year":"1962","journal-title":"Symp. Zool. Soc. Lond."},{"key":"e_1_2_10_61_2","unstructured":"Stuen S.2003.Anaplasma phagocytophilum(formerlyEhrlichia phagocytophila) infection in sheep and wild ruminants in Norway: a study on clinical manifestation distribution and persistence.Doctor Philosophiae thesis Norwegian College of Veterinary Medicine ."},{"key":"e_1_2_10_62_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.6.2237-2242.2001"},{"key":"e_1_2_10_63_2","doi-asserted-by":"publisher","DOI":"10.1017\/S003118200100107X"},{"key":"e_1_2_10_64_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268898001708"},{"key":"e_1_2_10_65_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.1997.tb00311.x"},{"key":"e_1_2_10_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(98)00138-1"},{"key":"e_1_2_10_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(82)90032-9"},{"key":"e_1_2_10_68_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700630103"},{"key":"e_1_2_10_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(82)90047-0"},{"key":"e_1_2_10_70_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2000.62.29"},{"key":"e_1_2_10_71_2","unstructured":"Snodgrass D.R.1974.Studies on bovine petechial fever and ovine tick\u2010borne fever.Ph.D. thesis University of Edinburgh Edinburgh Scotland ."},{"key":"e_1_2_10_72_2","first-page":"198","article-title":"Tick\u2010borne fever in young lambs","volume":"59","author":"McEwen A.D.","year":"1947","journal-title":"Vet. Rec."},{"key":"e_1_2_10_73_2","first-page":"767","article-title":"A note on the occurrence of tick\u2010borne fever in cattle in Scotland with comparative studies of bovine and ovine strains of the organism","volume":"72","author":"Foggie A.","year":"1960","journal-title":"Vet. Rec."},{"key":"e_1_2_10_74_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.118.15.415"},{"key":"e_1_2_10_75_2","first-page":"468","article-title":"Tick\u2010borne fever as a cause of abortion in sheep","volume":"62","author":"Jamieson S.","year":"1950","journal-title":"Vet. Rec."},{"key":"e_1_2_10_76_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.62.32.465"},{"key":"e_1_2_10_77_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.62.39.577"},{"key":"e_1_2_10_78_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.136.5.127"},{"key":"e_1_2_10_79_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2003.tb07406.x"},{"key":"e_1_2_10_80_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.111.22.512-b"},{"key":"e_1_2_10_81_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.133.16.398"},{"key":"e_1_2_10_82_2","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1186\/BF03548425","article-title":"Listeric septicaemia in sheep associated with tick\u2010borne fever (Ehrlichiosis ovis)","volume":"18","author":"Gronstol H.","year":"1977","journal-title":"Acta Vet. Scand."},{"key":"e_1_2_10_83_2","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1186\/BF03546841","article-title":"Listeriosis in sheep: tick\u2010borne fever used as a model to study predisposing factors","volume":"21","author":"Gronstol H.","year":"1980","journal-title":"Acta Vet. Scand."},{"key":"e_1_2_10_84_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113970"},{"key":"e_1_2_10_85_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(00)02324-3"},{"key":"e_1_2_10_86_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(70)90081-2"},{"key":"e_1_2_10_87_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(82)90060-8"},{"key":"e_1_2_10_88_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(87)90026-0"},{"key":"e_1_2_10_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0368-1742(56)80029-5"},{"key":"e_1_2_10_90_2","first-page":"70","article-title":"Effect of Cytoecetes phagocytophila on phagocytosis by neutrophils in sheep","volume":"32","author":"Batungbacal M.R.","year":"1995","journal-title":"Phil. J. Vet. Med."},{"key":"e_1_2_10_91_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2427(02)00038-7"},{"key":"e_1_2_10_92_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(08)80255-1"},{"key":"e_1_2_10_93_2","doi-asserted-by":"publisher","DOI":"10.1053\/jcpa.1998.0287"},{"key":"e_1_2_10_94_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.4.1995-2001.2003"},{"key":"e_1_2_10_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2427(03)00101-6"},{"key":"e_1_2_10_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5288(94)90107-4"},{"key":"e_1_2_10_97_2","unstructured":"Gokce I.H.1998.Studies on the effects ofEhrlichia(Cytoecetes)phagocytophilaon some cellular immune responses in sheep.Ph.D. thesis University of Liverpool Liverpool England ."},{"key":"e_1_2_10_98_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(87)90075-2"},{"key":"e_1_2_10_99_2","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5288(91)90028-M"},{"key":"e_1_2_10_100_2","doi-asserted-by":"publisher","DOI":"10.1086\/315641"},{"key":"e_1_2_10_101_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1967.tb01327.x"},{"key":"e_1_2_10_102_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1967.tb05146.x"},{"key":"e_1_2_10_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(82)90034-2"},{"key":"e_1_2_10_104_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(99)00050-3"},{"key":"e_1_2_10_105_2","doi-asserted-by":"crossref","first-page":"5834","DOI":"10.1128\/IAI.67.11.5834-5840.1999","article-title":"Emergence of Anaplasma marginale antigenic variants during persistent rickettsemia","volume":"67","author":"French D.M.","year":"1999","journal-title":"Infect. Immunol."},{"key":"e_1_2_10_106_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.25.17828"},{"key":"e_1_2_10_107_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2915.2002.00362.x"},{"key":"e_1_2_10_108_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.4.2071-2078.2003"},{"key":"e_1_2_10_109_2","first-page":"132","article-title":"An outbreak of tick\u2010borne fever in bovines","volume":"68","author":"Venn J.A.J.","year":"1956","journal-title":"Vet. Rec."},{"key":"e_1_2_10_110_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0931-1793.1999.00211.x"},{"key":"e_1_2_10_111_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(68)90102-3"},{"key":"e_1_2_10_112_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(84)90040-2"},{"key":"e_1_2_10_113_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0450.1998.tb00783.x"},{"key":"e_1_2_10_114_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0931-1793.1999.00210.x"},{"key":"e_1_2_10_115_2","first-page":"1081","article-title":"Tick\u2010borne fever as a cause of abortion and still\u2010births in cattle","volume":"76","author":"Wilson J.E.","year":"1964","journal-title":"Vet. Rec."},{"key":"e_1_2_10_116_2","first-page":"339","article-title":"Attempts to reproduce the pyemia associated with tick bite","volume":"53","author":"Taylor A.W.","year":"1941","journal-title":"Vet. Rec."},{"key":"e_1_2_10_117_2","doi-asserted-by":"publisher","DOI":"10.1053\/jcpa.2002.0574"},{"key":"e_1_2_10_118_2","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0034-5288(18)30890-7","article-title":"Use of counter immunoelectrophoresis in the detection of antibodies to tick\u2010borne fever","volume":"45","author":"Webster K.A.","year":"1988","journal-title":"Res. Vet. Sci."},{"key":"e_1_2_10_119_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(89)90025-4"},{"key":"e_1_2_10_120_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2004.12.002"},{"key":"e_1_2_10_121_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.3.1309-1317.2005"},{"key":"e_1_2_10_122_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.79.4.101"},{"key":"e_1_2_10_123_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.83.20.507"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1196%2Fannals.1374.084","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1196\/annals.1374.084","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T15:09:56Z","timestamp":1695654596000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1196\/annals.1374.084"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":122,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1196\/annals.1374.084"],"URL":"https:\/\/doi.org\/10.1196\/annals.1374.084","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}