{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:25:55Z","timestamp":1762100755567},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,12,13]],"date-time":"2007-12-13T00:00:00Z","timestamp":1197504000000},"content-version":"vor","delay-in-days":42,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:p><jats:bold><jats:sc>Abstract<\/jats:sc>:\u2002<\/jats:bold>  <jats:bold>In bone, parathyroid hormone (PTH) exerts either a catabolic or an anabolic effect depending on its method of administration. This paradoxical action has led to the use of PTH as an effective treatment for osteoporosis. The Wnt family of signaling proteins has a critical role in multiple events, which are necessary for proper animal development and survival, yet their exact method of action in bone remains elusive. We have uncovered a novel link between Wnt\u20104 and PTH. We think that, in bone, Wnt\u20104 signaling in response to PTH implicates cross\u2010talk of multiple signaling pathways. This work hopes to further elucidate Wnt signaling in bone and provide greater understanding of PTH's anabolic effects in bone.<\/jats:bold> <\/jats:p>","DOI":"10.1196\/annals.1402.047","type":"journal-article","created":{"date-parts":[[2007,12,14]],"date-time":"2007-12-14T19:53:17Z","timestamp":1197661997000},"page":"354-359","source":"Crossref","is-referenced-by-count":27,"title":["Parathyroid Hormone Stimulation of Noncanonical Wnt Signaling in Bone"],"prefix":"10.1111","volume":"1116","author":[{"given":"MARIKA K.","family":"BERGENSTOCK","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NICOLA C.","family":"PARTRIDGE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,12,13]]},"reference":[{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113275"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-14-6-690"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00283-1"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1210\/endo.138.11.5505"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.20438"},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.1210\/endo-110-2-506"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1999.14.9.1504"},{"key":"e_1_2_2_9_2","first-page":"73","article-title":"The prevention and treatment of osteoporosis: a review","volume":"7","author":"Cosman F.","year":"2005","journal-title":"Med. 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