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Analysis has been complicated by the absence, until very recently, of accepted objective definitions of severity of the illness and response to therapy as well as variable patient selection, timing of surgery, type of surgery, and methods of analysis of results. Without resolution of these issues by properly designed prospective studies, there can be no unequivocally valid comparison of the various thymectomy techniques. In this review, attempts have been made to clarify some of the controversial issues concerning the selection of a thymectomy technique in the treatment of nonthymomatous MG and to make limited recommendations based on the best available evidence.<\/jats:p>","DOI":"10.1196\/annals.1405.004","type":"journal-article","created":{"date-parts":[[2008,6,20]],"date-time":"2008-06-20T23:23:28Z","timestamp":1214004208000},"page":"315-328","source":"Crossref","is-referenced-by-count":99,"title":["<i>Thymectomy for Nonthymomatous<\/i>Myasthenia Gravis"],"prefix":"10.1111","volume":"1132","author":[{"given":"Joshua R.","family":"Sonett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred","family":"Jaretzki III","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,6,28]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.Suppl_5.52S"},{"key":"e_1_2_11_3_2","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0022-5223(19)40309-7","article-title":"Distribution of thymic tissue at the anterior mediastinum: current procedures in thymectomy","volume":"70","author":"Masaoka A.","year":"1975","journal-title":"J. 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