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CM has been recognized as a complicating factor in pregnancy since at least the 1940s, and seems to be a relatively uncommon infection during pregnancy. The disease presentation during pregnancy includes a wide clinical spectrum that ranges from mild influenza\u2010like illness and pneumonia, especially in the first two trimesters of pregnancy. The third trimester of pregnancy is a time of high risk for dissemination. Immunologic and hormonal changes during pregnancy and the postpartum period may account for any increased frequency and severity of disease observed during pregnancy. Early diagnosis and appropriate aggressive therapeutic intervention with careful monitoring usually result in good outcome.<\/jats:bold> <\/jats:p>","DOI":"10.1196\/annals.1406.008","type":"journal-article","created":{"date-parts":[[2007,10,17]],"date-time":"2007-10-17T22:34:18Z","timestamp":1192660458000},"page":"358-364","source":"Crossref","is-referenced-by-count":21,"title":["Coccidioidomycosis and Pregnancy"],"prefix":"10.1111","volume":"1111","author":[{"given":"IRENE M.","family":"SPINELLO","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ROYCE H.","family":"JOHNSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SHEHLA","family":"BAQI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,10,10]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/16.3.349"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.86.3.14S"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2006.04.022"},{"key":"e_1_2_9_5_2","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1128\/iai.40.2.478-485.1983","article-title":"Relationship of progesterone and estradiol\u2010binding proteins in Coccidioides immitis to coccidioidal dissemination in pregnancy","volume":"40","author":"Powell B.L.","year":"1983","journal-title":"Infect. 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