{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T03:17:31Z","timestamp":1770434251857,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,10,10]],"date-time":"2007-10-10T00:00:00Z","timestamp":1191974400000},"content-version":"vor","delay-in-days":39,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:p><jats:bold><jats:sc>Abstract<\/jats:sc>:\u2002<\/jats:bold>  <jats:bold>Coccidioidomycosis is a recognized opportunistic infection in those with HIV\u20101 infection. The major risk factor is immunodeficiency, particularly when the peripheral blood CD4 T lymphocyte count is below 250\/\u03bcL. There are many manifestations of coccidioidomycosis during HIV\u20101 infection, including diffuse, reticulonodular pneumonia, focal primary pneumonia, and disease disseminated beyond the thoracic cavity. Diagnosis is based on serology, culture and histopathologic identification. Two therapeutic modalities are currently available, the polyene antifungal amphotericin B and the triazole antifungals. Of the latter, the most experience is with the triazoles fluconazole and itraconazole. There are increasing data regarding drug interactions between triazoles and antiretroviral agents. The duration of treatment of coccidioidomycosis in those with HIV\u20101 infection is not established and in many patients it is either prolonged or life\u2010long. Adherence to antiretroviral therapy is important in preventing recurrence.<\/jats:bold> <\/jats:p>","DOI":"10.1196\/annals.1406.033","type":"journal-article","created":{"date-parts":[[2007,10,17]],"date-time":"2007-10-17T22:34:18Z","timestamp":1192660458000},"page":"336-342","source":"Crossref","is-referenced-by-count":20,"title":["Coccidioidomycosis in Persons Infected with HIV\u20101"],"prefix":"10.1111","volume":"1111","author":[{"given":"NEIL M.","family":"AMPEL","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,10,10]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/srin.2001.29301"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/444502"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90054-S"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-133-9-200011070-00009"},{"key":"e_1_2_7_6_2","first-page":"559","article-title":"Coccidioidomycosis. Part I","volume":"117","author":"Drutz D.J.","year":"1978","journal-title":"Am. Rev. Respir. Dis."},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198404123101511"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02447922"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-106-3-372"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199011000-00006"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.3.563"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/171.4.961"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1086\/313843"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199803263381301"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1086\/315401"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1086\/501133"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/20.5.1281"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-006-0062-5"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199007000-00015"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1053\/srin.2001.29315"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1086\/496991"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-3-199602010-00004"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-280X.1999.00227.x"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki184"},{"key":"e_1_2_7_25_2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1128\/AAC.42.2.223","article-title":"Effect of fluconazole on indinavir pharmacokinetics in human immunodeficiency virus\u2010infected patients","volume":"42","author":"De Wit S","year":"1998","journal-title":"Antimicrob. Agents Chemother."},{"key":"e_1_2_7_26_2","first-page":"1104","article-title":"Evaluation of the effect of fluconazole on the pharmacokinetics of ritonavir","volume":"25","author":"Cato A.","year":"1997","journal-title":"Drug Metab. Dispos."},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0306-5251.2001.01409.x"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1086\/382675"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2006.04.004"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1517\/17425255.1.3.473"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200645070-00002"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1196%2Fannals.1406.033","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1196\/annals.1406.033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T14:01:46Z","timestamp":1695650506000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1196\/annals.1406.033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1196\/annals.1406.033"],"URL":"https:\/\/doi.org\/10.1196\/annals.1406.033","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}