{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T03:46:05Z","timestamp":1770522365427,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,9,27]],"date-time":"2007-09-27T00:00:00Z","timestamp":1190851200000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:p><jats:bold><jats:sc>Abstract<\/jats:sc>:\u2002<\/jats:bold>  <jats:bold>Opsoclonus\u2013myoclonus syndrome (OMS) is a rare neurologic disorder comprising the main symptoms of eye\u2010movement disturbances, muscle jerks, and severe ataxia. In children and adults, some cases are associated with a tumor as a paraneoplastic syndrome, whereas in children the paraneoplastic form is almost exclusively associated with neuroblastoma. The detection of autoantibodies in some OMS sera led to the hypothesis that the syndrome is of autoimmune origin. Beside autoantibodies against intracellular proteins, such as anti\u2010Hu, \u03b1\u2010enolase, and KHSRP, specific binding of autoantibodies to the surface of neuroblastoma cells and cerebellar granular neurons have been found. Antiproliferative and proapoptotic effects of these autoantibodies on neuroblastoma cell lines were noted as well. These results support the concept of a humoral autoimmune process in the pathogenesis of OMS<\/jats:bold>.<\/jats:p>","DOI":"10.1196\/annals.1423.027","type":"journal-article","created":{"date-parts":[[2007,10,2]],"date-time":"2007-10-02T20:20:20Z","timestamp":1191356420000},"page":"256-260","source":"Crossref","is-referenced-by-count":25,"title":["New Autoantibodies in Pediatric Opsoclonus\u2013Myoclonus Syndrome"],"prefix":"10.1111","volume":"1110","author":[{"given":"A.","family":"KIRSTEN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"BECK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"F\u00dcHLHUBER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"KAPS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"KREUTZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"KORFEI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"SCHMITT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.T.","family":"PREISSNER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"BLAES","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,9,27]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.05.016"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-199619010-00001"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199512000-00014"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197602)37:2<846::AID-CNCR2820370233>3.0.CO;2-L"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra023009"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.62.9.1526"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20125"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(94)90127-9"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(87)90088-9"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2005.08.018"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(97)70272-5"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10462"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.16-03-01114.1996"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2005.10.014"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20539"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/PL00000910"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1996.75.6.2229"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00344353"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2005.078105"},{"key":"e_1_2_4_21_2","doi-asserted-by":"publisher","DOI":"10.3109\/15563658208990383"},{"key":"e_1_2_4_22_2","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1160\/TH05-05-0369","article-title":"The nine residue plasminogen\u2010binding motif of the pneumococcal enolase is the major cofactor of plasmin\u2010mediated degradation of extracellular matrix, dissolution of fibrin and transmigration","volume":"94","author":"Bergmann S.","year":"2005","journal-title":"Thromb. 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