{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:41:07Z","timestamp":1788691267598,"version":"build-2803163510"},"reference-count":72,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,6,28]],"date-time":"2008-06-28T00:00:00Z","timestamp":1214611200000},"content-version":"vor","delay-in-days":58,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:p>Quantum dots (QDs) are nanoscale inorganic particles generally composed of II\u2013VI and III\u2013V elements. Recently, QDs have received great interest in biological applications because of their unique and fascinating optical properties. In this short review, we introduce the synthesis of luminescent QDs in the aqueous phase and characterize certain fundamental parameters of luminescent QDs synthesized in the aqueous phase by fluorescence correlation spectroscopy (FCS), which include, for example, their dynamic diameters and surface charges. Meanwhile, combining with some ensemble spectroscopy techniques, we applied FCS to investigate the quenching process and mechanism of heavy metal ions (e.g., Ag<jats:sup>+<\/jats:sup>) on CdTe QDs, as well as the aggregation and subsequent photoactivation process of 3\u2010mercaptopropionic acid\u2013capping CdTe QDs induced by laser irradiation. Our preliminary results demonstrate that FCS is a sensitive and efficient tool to characterize fluorescent nanoparticles, such as QDs, at the single\u2010molecule detection level.<\/jats:p>","DOI":"10.1196\/annals.1430.029","type":"journal-article","created":{"date-parts":[[2008,7,2]],"date-time":"2008-07-02T23:19:18Z","timestamp":1215040758000},"page":"253-261","source":"Crossref","is-referenced-by-count":15,"title":["<i>Characterization of Water\u2010soluble Luminescent Quantum Dots by Fluorescence Correlation Spectroscopy<\/i>"],"prefix":"10.1111","volume":"1130","author":[{"given":"Chaoqing","family":"Dong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jicun","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,6,28]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.271.5251.933"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp9535506"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199300411"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1104274"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1039\/b404498n"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.89.186802"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp072463y"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.281.5385.2016"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.281.5385.2013"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt767"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt764"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt927"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1088\/0957-4484\/14\/7\/201"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-7799(03)00209-9"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0958-1669(02)00282-3"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja035848c"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat961"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl015565n"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja037088b"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja00072a025"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl0155532"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0027766"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl0155126"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja017002j"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp027160c"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3773(20020703)41:13<2368::AID-ANIE2368>3.0.CO;2-G"},{"key":"e_1_2_8_28_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.281.5385.2016"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl034054t"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.152463399"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja002535y"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp0105488"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja016424q"},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200400071"},{"key":"e_1_2_8_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/bbpc.19961001104"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp025541k"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4095(199905)11:7<552::AID-ADMA552>3.0.CO;2-Q"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200305653"},{"key":"e_1_2_8_39_2","doi-asserted-by":"publisher","DOI":"10.1039\/b412686f"},{"key":"e_1_2_8_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.materresbull.2005.05.022"},{"key":"e_1_2_8_41_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp0539324"},{"key":"e_1_2_8_42_2","doi-asserted-by":"publisher","DOI":"10.1021\/cm034081k"},{"key":"e_1_2_8_43_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl025662w"},{"key":"e_1_2_8_44_2","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.29.705"},{"key":"e_1_2_8_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/bip.1974.360130102"},{"key":"e_1_2_8_46_2","doi-asserted-by":"publisher","DOI":"10.1002\/bip.1974.360130102"},{"key":"e_1_2_8_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0104(74)85005-6"},{"key":"e_1_2_8_48_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00185777"},{"key":"e_1_2_8_49_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi0118512"},{"key":"e_1_2_8_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1046-2023(02)00306-7"},{"key":"e_1_2_8_51_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl035172j"},{"key":"e_1_2_8_52_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac050035n"},{"key":"e_1_2_8_53_2","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200500108"},{"key":"e_1_2_8_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2005.05.034"},{"key":"e_1_2_8_55_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp070999d"},{"key":"e_1_2_8_56_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp074961c"},{"key":"e_1_2_8_57_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.1482785"},{"key":"e_1_2_8_58_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp036907b"},{"key":"e_1_2_8_59_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja051095d"},{"key":"e_1_2_8_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/bip.1978.360170208"},{"key":"e_1_2_8_61_2","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200500456"},{"key":"e_1_2_8_62_2","doi-asserted-by":"publisher","DOI":"10.1021\/nl0342491"},{"key":"e_1_2_8_63_2","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.86.3132"},{"key":"e_1_2_8_64_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp0352884"},{"key":"e_1_2_8_65_2","volume-title":"Optical Properties of Semiconductor Quantum Dots","author":"Woggon U.","year":"1997"},{"key":"e_1_2_8_66_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp060279r"},{"key":"e_1_2_8_67_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0123599"},{"key":"e_1_2_8_68_2","doi-asserted-by":"publisher","DOI":"10.1021\/cm049172b"},{"key":"e_1_2_8_69_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp037941t"},{"key":"e_1_2_8_70_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp048948t"},{"key":"e_1_2_8_71_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp001771s"},{"key":"e_1_2_8_72_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp071082h"},{"key":"e_1_2_8_73_2","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200500530"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1196%2Fannals.1430.029","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1196\/annals.1430.029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T06:27:24Z","timestamp":1695623244000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1196\/annals.1430.029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":72,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1196\/annals.1430.029"],"URL":"https:\/\/doi.org\/10.1196\/annals.1430.029","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}