{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T20:17:09Z","timestamp":1774124229236,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,6,28]],"date-time":"2008-06-28T00:00:00Z","timestamp":1214611200000},"content-version":"vor","delay-in-days":850,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Academic Emergency Medicine"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:p> <jats:italic>\n            <jats:bold>Objectives:<\/jats:bold>\n          <\/jats:italic> To determine interobserver agreement between radiologists for computed tomography (CT) angiography and venography. CT venography of the lower extremities combined with standard CT angiography of the chest may result in an increased overall diagnosis rate of venous thromboembolism (pulmonary embolism or deep venous thrombosis).<\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Methods:<\/jats:bold>\n          <\/jats:italic> The study had a retrospective cohort design. The population consisted of emergency department patients who were evaluated for suspected pulmonary embolism. A random sample of 50 patients diagnosed and treated for venous thromboembolism and 50 age\u2010 and gender\u2010matched patients whose CT angiograms and venograms were read as negative were enrolled. The original reading (R1) was compared with readings of two study radiologists: R2, a general radiologist, and R3, a radiologist with fellowship training in cross\u2010sectional imaging. All readers were blinded to each other.<\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Results:<\/jats:bold>\n          <\/jats:italic> Both R2 and R3 found both CT angiogram and venogram components technically adequate in 95% (95% CI = 89% to 98%) and 86% (95% CI = 78% to 92%) of studies, respectively. The agreement was very good for CT angiography (lowest agreement = 92%; lowest <jats:italic>\u03ba<\/jats:italic>= 0.83) and was good for CT venography (85%, <jats:italic>\u03ba<\/jats:italic>= 0.65). In nine cases, R1 read the CT angiogram as negative but the venogram as positive for DVT, whereas both R2 and R3 read both components as negative in four of these nine, suggesting a false\u2010positive isolated DVT rate of 44% (95% CI = 19% to 73%). In no case did R1 read both scan components as negative when R2 and R3 agreed on presence of pulmonary embolism or DVT.<\/jats:p><jats:p> <jats:italic>\n            <jats:bold>Conclusions:<\/jats:bold>\n          <\/jats:italic> Diagnosis of pulmonary embolism on CT angiography is more reliable than diagnosis of isolated DVT on CT venography.<\/jats:p>","DOI":"10.1197\/j.aem.2005.09.013","type":"journal-article","created":{"date-parts":[[2006,2,23]],"date-time":"2006-02-23T01:44:14Z","timestamp":1140659054000},"page":"295-301","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Interobserver Agreement for the Diagnosis of Venous Thromboembolism on Computed Tomography Chest Angiography and Indirect Venography of the Lower Extremities in Emergency Department Patients"],"prefix":"10.1111","volume":"13","author":[{"given":"Peter B.","family":"Richman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shari","family":"Dominguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Kasper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Friese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Wood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Collins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A.","family":"Kline","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,6,28]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.16.2012"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1538-7836.2003.00370.x"},{"key":"e_1_2_1_4_1","first-page":"1886","article-title":"Non\u2010traumatic thoracic emergencies: CT diagnosis of acute pulmonary embolism\u2014the first 10 years.","volume":"12","author":"Gyahe B","year":"2002","journal-title":"Emerg Radiol."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/107602960100700202"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(00)70137-5"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0899-7071(01)00366-7"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003300000539"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.4065\/77.2.130"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-135-2-200107170-00008"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.71.852.10318998"},{"key":"e_1_2_1_12_1","first-page":"973","article-title":"11. Compression ultrasonography of the leg veins in patients with clinically suspected pulmonary embolism. Is a more extensive assessment of compressibility useful?","volume":"84","year":"2002","journal-title":"Thromb Haemost."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(00)70026-6"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.175.4.1750997"},{"key":"e_1_2_1_15_1","first-page":"327","article-title":"CT x\u2010ray evaluation of abdominal and pelvic veins in patients suspected of acute pulmonary embolism with negative Doppler sonography [French].","volume":"79","author":"Ferretti GR","year":"1998","journal-title":"J Radiol."},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.219.2.r01ma26498"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.176.4.1761035"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.176.4.1761043"},{"key":"e_1_2_1_19_1","first-page":"271","article-title":"Combined CT venography of the lower limbs and spiral CT angiography of pulmonary arteries in acute pulmonary embolism: preliminary results of a prospective study.","volume":"83","author":"Ghaye B","year":"2000","journal-title":"JBR-BTR: Organe de la Societe Royale Belge de Radiologie."},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.216.3.r00se44744"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.170.4.9530042"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1538-7836.2003.00231.x"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.2004.tb00717.x"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.200.3.8756918"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.177.2.1770319"},{"key":"e_1_2_1_26_1","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00330-002-1588-7","article-title":"Prospective comparison of helical CT with angiography in pulmonary embolism: global and selective vascular territory analysis. 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