{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T07:25:59Z","timestamp":1787901959194,"version":"build-2784847793"},"reference-count":19,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"6","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Clinical Cancer Informatics"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec><jats:title>PURPOSE<\/jats:title><jats:p> To evaluate the completeness of information for research and quality assessment through a linkage between cancer registry data and electronic health record (EHR) data refined by ASCO's health technology platform CancerLinQ. <\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p> A probabilistic data linkage between Iowa Cancer Registry (ICR) and an Iowa oncology clinic through CancerLinQ data was conducted for cases diagnosed between 2009 and 2018. Demographic, cancer, and treatment variables were compared between data sources for the same patients, all of whom were diagnosed with one primary cancer. Treatment data and compliance with quality measures were compared among those with breast or prostate cancer; SEER-Medicare data served as a comparison. Variables captured only in CancerLinQ data (smoking, pain, and height\/weight) were evaluated for completeness. <\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p> There were 6,175 patients whose data were linked between ICR and CancerLinQ data sets. Of those, 4,291 (70%) were diagnosed with one primary cancer and were included in analyses. Demographic variables were comparable between data sets. Proportions of people receiving hormone therapy (30% v 26%, P &lt; .0001) or immunotherapy (22% v 12%, P &lt; .0001) were significantly higher in CancerLinQ data compared with ICR data. ICR data contained more complete TNM stage, human epidermal growth factor receptor 2 testing, and Gleason score information. Compliance with quality measures was generally highest in SEER-Medicare data followed by the combined ICR-CancerLinQ data. CancerLinQ data contained smoking, pain, and height\/weight information within one month of diagnosis for 88%, 52%, and 76% of patients, respectively. <\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p> Linking CancerLinQ EHR data with cancer registry data led to more complete data for each source respectively, as registry data provides definitive diagnosis and more complete stage information and laboratory results, whereas EHR data provide more detailed treatment data and additional variables not captured by registries. <\/jats:p><\/jats:sec>","DOI":"10.1200\/cci.21.00149","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T20:00:24Z","timestamp":1651176024000},"update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":13,"title":["Cancer Registry Data Linkage of Electronic Health Record Data From ASCO's CancerLinQ: Evaluation of Advantages, Limitations, and Lessons Learned"],"prefix":"10.1200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2409-1018","authenticated-orcid":false,"given":"Mary E.","family":"Charlton","sequence":"first","affiliation":[{"name":"Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA"},{"name":"Iowa Cancer Registry, College of Public Health, University of Iowa, Iowa City, IA"},{"name":"Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0041-1654","authenticated-orcid":false,"given":"Amanda R.","family":"Kahl","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA"},{"name":"Iowa Cancer Registry, College of Public Health, University of Iowa, Iowa City, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8802-7686","authenticated-orcid":false,"given":"Bradley D.","family":"McDowell","sequence":"additional","affiliation":[{"name":"Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0869-6316","authenticated-orcid":false,"given":"Robert S.","family":"Miller","sequence":"additional","affiliation":[{"name":"CancerLinQ\u00ae, American Society of Clinical Oncology, Alexandria, VA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6967-7085","authenticated-orcid":false,"given":"George","family":"Komatsoulis","sequence":"additional","affiliation":[{"name":"CancerLinQ\u00ae, American Society of Clinical Oncology, Alexandria, VA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob E.","family":"Koskimaki","sequence":"additional","affiliation":[{"name":"CancerLinQ\u00ae, American Society of Clinical Oncology, Alexandria, VA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4565-4556","authenticated-orcid":false,"given":"Donna R.","family":"Rivera","sequence":"additional","affiliation":[{"name":"Surveillance, Epidemiology and End Results Program, Division of Cancer Control and Population Sciences (DCCPS), National Cancer Institute (NCI), National Institutes of Health (NIH), Rockville, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Cronin","sequence":"additional","affiliation":[{"name":"Surveillance, Epidemiology and End Results Program, Division of Cancer Control and Population Sciences (DCCPS), National Cancer Institute (NCI), National Institutes of Health (NIH), Rockville, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1200\/CCI.20.00064"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_160113"},{"key":"b3","first-page":"3","volume":"2020","author":"Enewold L","year":"2020","journal-title":"JNCI Monogr"},{"key":"b4","volume-title":"Match*Pro Software","author":"National Cancer Institute"},{"key":"b5","volume-title":"SNOMED CT","author":"National Library of Medicine"},{"key":"b6","volume-title":"RxNorm RxCUI Codes for Cancer Therapies","author":"Carnahan R"},{"key":"b7","volume-title":"SEER*Rx Interactive Antineoplastic Drugs Database","author":"National Cancer Institute SEER Program"},{"key":"b8","volume-title":"QOPI Reporting Registry","author":"American Society of Clinical Oncology and Association for Clinical Oncology","year":"2021"},{"key":"b9","volume-title":"Quality ID #449 (NQF 1857): HER2 Negative or Undocumented Breast Cancer Patients Spared Treatment With HER2-Targeted Therapies","year":"2019"},{"key":"b10","volume-title":"Quality ID #450 (NQF 1858): Trastuzumab Received by Patients With AJCC Stage I (T1c) \u2013 III and HER2 Positive Breast Cancer Receiving Adjuvant Chemotherapy","year":"2020"},{"key":"b11","volume-title":"Quality ID #104 (NQF 0390): Prostate Cancer: Combination Androgen Deprivation Therapy for High Risk or Very High Risk Prostate Cancer","year":"2019"},{"key":"b12","volume-title":"CanMED","author":"National Cancer Institute"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1093\/jncimonographs\/lgz034"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000000073"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000196978.34283.a6"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/94.11.835"},{"key":"b17","volume-title":"CancerLinQ","author":"ASCO","year":"2021"},{"key":"b18","volume-title":"HL7 FHIR Implementation Guide: Minimal Common Oncology Data Elements (mCODE) Release 1\u2014US Realm | STU1","author":"Miller R","year":"2019"},{"key":"b19","volume-title":"ONC\u2019s Cures Act Final Rule","author":"Office of the National Coordinator for Health Information Technology"}],"container-title":["JCO Clinical Cancer Informatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/CCI.21.00149","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T11:00:42Z","timestamp":1653822042000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/CCI.21.00149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1200\/CCI.21.00149"],"URL":"https:\/\/doi.org\/10.1200\/cci.21.00149","relation":{},"ISSN":["2473-4276"],"issn-type":[{"value":"2473-4276","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"2021-08-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-27","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2100149"}}