{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:52:18Z","timestamp":1753883538257,"version":"3.41.2"},"reference-count":39,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"11","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Glob Oncol"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n            <jats:title>PURPOSE<\/jats:title>\n            <jats:p>To evaluate baseline distress among patients with breast cancer in Botswana, and assess the impact of culturally tailored peer survivor video narratives on distress and its mediators.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS<\/jats:title>\n            <jats:p>We enrolled patients with stage I-IV breast cancer at Princess Marina Hospital. A Setswana-translated National Comprehensive Cancer Network distress thermometer (DT) and problem list (PL) were used for distress screening. DT score of \u22654 was considered a positive screen for moderate to high (moderate-high) distress. We analyzed independent PL factors associated with moderate-high distress using logistic regression. Participants then watched one to two videos and completed a postintervention DT\/PL assessment after each video at 4 and 8 weeks. We conducted descriptive statistics to explore the impact of the videos.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS<\/jats:title>\n            <jats:p>\n              One hundred six participants were enrolled, of whom 103 completed baseline DT and 106 completed baseline PL. Sixty-seven percent (69\/103) of participants screened positive for moderate-high distress at baseline. Fear (odds ratio [OR], 11.25 [95% CI, 1.66 to 76.49];\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              = .01) and appearance (OR, 4.96 [95% CI, 1.03 to 23.80];\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              = .046) were PL factors significantly associated with moderate-high distress in the multivariable model. Sixty-eight and 47 participants completed postvideo assessments at approximately 4 and approximately 8 weeks, respectively. The greatest impact was observed at 8 weeks after watching two videos\u201429.8% of participants with moderate-high distress had no or mild distress. Similarly, there was a 29% (44%-15%;\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              = .005) and 17% (32%-15%;\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              = .03) absolute decrease from baseline to 8 weeks, in the proportion of patients who identified fear and appearance as sources of distress, respectively.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSION<\/jats:title>\n            <jats:p>Two thirds of patients with breast cancer screened positive for moderate-high distress. Fear and appearance were sources of distress significantly associated with a positive screen. Our results show promising potential of peer survivor videos to mitigate distress and its potential mediators among patients with breast cancer.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1200\/go-24-00474","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T19:59:10Z","timestamp":1750276750000},"update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Baseline Distress and Effectiveness of Survivor Video Narratives on Cancer-Associated Distress in Botswana: A Pilot Study"],"prefix":"10.1200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5631-1567","authenticated-orcid":true,"given":"Yehoda M.","family":"Martei","sequence":"first","affiliation":[{"name":"Department of Medicine (Hematology-Oncology Division), University of Pennsylvania, Philadelphia, 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