{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T21:02:44Z","timestamp":1766523764955,"version":"3.48.0"},"reference-count":54,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"11","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Glob Oncol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE<\/jats:title>\n                    <jats:p>Colorectal cancer burden is increasing in Mexico. Population-based screening programs will be needed to address this public health challenge. Our objective was to explore the feasibility of offering colorectal cancer screening (CRCS) with a fecal immunochemical test (FIT) kit in the context of an existing door-to-door vaccination program in Mexico City.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The study was conducted in Mexico City in 2019-2020, before and during the onset of the COVID-19 pandemic. Design of the intervention was informed by focus group interviews with average-risk adults age 50-75 years served by a door-to-door vaccination program and interviews with primary care clinic and hospital staff serving this community. The intervention involved offering FIT to household members age 50-75 years during routine door-to-door immunization campaigns, with follow-up colonoscopy for those with abnormal results. Feasibility and acceptability of the intervention was evaluated through analysis of patient participation, clinical outcomes, and surveys.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 132\/178 (74.2%) eligible community participants accepted a FIT kit after receiving information from a trained health promoter. Mean age of participants was 62.0 (\u00b16.8) years, and most were women (n = 84, 63.6%). Among participants, 94 (71.2%) returned FIT for testing. Of these, 20 (21.3%) had an abnormal FIT result (\u226520 ngHg\/mL) and were offered colonoscopy. Of these, 10 (50%) completed the colonoscopy. Recruitment was halted due to the COVID-19 pandemic, which also became a barrier to colonoscopy completion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Offering CRCS with FIT during door-to-door vaccination activities was feasible and acceptable to outreach workers and patients. Further studies are needed to determine interventions and implementation strategies necessary for scale-up and the effectiveness within integrated health systems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1200\/go-25-00321","type":"journal-article","created":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T20:58:26Z","timestamp":1766523506000},"update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility of Providing Colorectal Cancer Screening in the Context of Door-to-Door Vaccination Activities in Mexico City"],"prefix":"10.1200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9741-2404","authenticated-orcid":true,"given":"Priscilla","family":"Espinosa-Tamez","sequence":"first","affiliation":[{"name":"University of California, San Francisco, San Francisco, CA"},{"name":"Center for Research on Population Health, National Institute of Public Health, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9689-498X","authenticated-orcid":true,"given":"Karla","family":"Unger-Salda\u00f1a","sequence":"additional","affiliation":[{"name":"CONAHCYT\u2014National Cancer Institute of Mexico, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minerva","family":"Salda\u00f1a-T\u00e9llez","sequence":"additional","affiliation":[{"name":"CONAHCYT\u2014National Cancer Institute of Mexico, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1465-8053","authenticated-orcid":true,"given":"Giovanna","family":"L\u00f3pez-Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Center for Research on Population Health, National Institute of Public Health, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0667-4255","authenticated-orcid":true,"given":"Hugo","family":"Sanchez-Blas","sequence":"additional","affiliation":[{"name":"Center for Research on Population Health, National Institute of Public Health, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis M","family":"Robles-Gonzalez","sequence":"additional","affiliation":[{"name":"Miguel Hidalgo District Health Jurisdiction, Mexico City's Health Department, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ang\u00e9lica","family":"Hern\u00e1ndez-Guerrero","sequence":"additional","affiliation":[{"name":"Servicio de Endoscop\u00eda, Instituto Nacional de Cancerolog\u00eda, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6753-0116","authenticated-orcid":true,"given":"Maria","family":"Del Carmen Manzano-Robleda","sequence":"additional","affiliation":[{"name":"Servicio de Endoscop\u00eda, Instituto Nacional de Cancerolog\u00eda, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"de Jes\u00fas Mart\u00ednez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Servicio de Endoscop\u00eda, Hospital General \u201cDr Rub\u00e9n Le\u00f1ero\u201d, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8643-1113","authenticated-orcid":true,"given":"Monica Isabel","family":"Meneses-Medina","sequence":"additional","affiliation":[{"name":"Departamento de Hematologia y Oncolog\u00eda, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael B.","family":"Potter","sequence":"additional","affiliation":[{"name":"University of California, San Francisco, San Francisco, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8471-4128","authenticated-orcid":true,"given":"Mart\u00edn","family":"Lajous","sequence":"additional","affiliation":[{"name":"Center for Research on Population Health, National Institute of Public Health, Mexico City, Mexico"},{"name":"Department of Global Health and Population, Harvard T.H. 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