{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:09:19Z","timestamp":1790179759627,"version":"4.1.0"},"reference-count":20,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"4","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Glob Oncol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE<\/jats:title>\n                    <jats:p>To describe cancer incidence, mortality, and mortality-to-incidence ratios (MIRs) in Africa in 2022 by age and country to inform cancer control planning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We conducted a descriptive analysis of GLOBOCAN 2022 estimates, summarizing age-standardized incidence rate (ASIR), mortality (ASMR) per 100,000, and MIR (ASMR\/ASIR). Two lenses were applied: age bands (0-19, 20-44, 45-69, \u226570 years) and country concentration curves, which identify the smallest set of countries accounting for 50% and 80% of the burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>In 2022, there were 1,154,584 new cancer cases and 754,574 deaths. Breast, cervix uteri, prostate, colorectal, and liver cancers dominated incidence, whereas liver, lung, cervix uteri, breast, and stomach cancers dominated mortality. Around 80% of incident cases occurred in 15 countries. MIR increased with age and was highest at \u226570 years. Liver, lung, stomach, and brain\/central nervous system cancers showed consistently high MIR. Cancer site profiles differed by life stage, with hematologic cancers predominating in childhood and adolescence and breast, cervix, prostate, and colorectal cancers predominating from mid-adulthood onward.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Cancer mortality in Africa is high, rises with age, and is concentrated in few countries. Age-band and country-concentration lenses identify priorities for human papillomavirus and hepatitis B vaccination, tobacco control, and oncology packages in high-burden settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1200\/go-25-00663","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T19:59:10Z","timestamp":1775851150000},"update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":5,"title":["Cancer in Africa, 2022: Incidence, Mortality, and Age-Patterned Fatality From GLOBOCAN Across 36 Cancer Types"],"prefix":"10.1200","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5335-2905","authenticated-orcid":true,"given":"Lawrence Ejike","family":"Ugwu","sequence":"first","affiliation":[{"name":"Faculty of Humanities, North-West University, Mafikeng, South Africa"},{"name":"Centre for Applied Psychology and Public Health in Africa, Enugu, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1796-4848","authenticated-orcid":true,"given":"Wojujutari Kenni","family":"Ajele","sequence":"additional","affiliation":[{"name":"Faculty of Humanities, North-West University, Mafikeng, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5522-7435","authenticated-orcid":true,"given":"Erhabor Sunday","family":"Idemudia","sequence":"additional","affiliation":[{"name":"Faculty of Humanities, North-West University, Mafikeng, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2631-285X","authenticated-orcid":false,"given":"Bruno","family":"Basil","sequence":"additional","affiliation":[{"name":"International Institute for Pathology and Forensic Science Research, David Umahi Federal University of Health Sciences, Uburu, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9493-1495","authenticated-orcid":true,"given":"Maria-Chidi Christiana","family":"Onyedibe","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Nigeria, Nsukka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6025-776X","authenticated-orcid":true,"given":"Runcie C.W.","family":"Chidebe","sequence":"additional","affiliation":[{"name":"Project PINK BLUE\u2014Health and Psychological Trust Centre, Abuja, Nigeria"},{"name":"Department of Sociology and Gerontology, Miami University, Oxford, OH"},{"name":"Scripps Gerontology Center, Miami University, Oxford, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9156-2989","authenticated-orcid":false,"given":"Cornelie","family":"Nienaber-Rousseau","sequence":"additional","affiliation":[{"name":"Centre of Excellence for Nutrition, North-West University, Potchefstroom, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uzoamaka F.","family":"Ugwoke","sequence":"additional","affiliation":[{"name":"Psychology Department, Enugu State University of Science and Technology, Enugu, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candy T.","family":"Khohliwe","sequence":"additional","affiliation":[{"name":"Wikimedia Community User Group Botswana, Gaborone, Botswana"},{"name":"Innovate Learn Africa, Gaborone, Botswana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","reference":[{"key":"e_1_3_7_2_2","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Ferlay J","year":"2024","unstructured":"Ferlay J, Laversanne M, Ervik M, et al. 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Geneva, Switzerland, WHO, 2023"},{"key":"e_1_3_7_17_2","volume-title":"WHO Report on the Global Tobacco Epidemic, 2023: Protect People from Tobacco Smoke","author":"World Health Organization","year":"2023","unstructured":"World Health Organization: WHO Report on the Global Tobacco Epidemic, 2023: Protect People from Tobacco Smoke. Geneva, Switzerland, WHO, 2023. ISBN: 978-92-4-007716-4."},{"key":"e_1_3_7_18_2","volume-title":"WHO Report on the Global Tobacco Epidemic 2021: Country Profile\u2014South Africa","author":"World Health Organization","year":"2021","unstructured":"World Health Organization: WHO Report on the Global Tobacco Epidemic 2021: Country Profile\u2014South Africa. Geneva, Switzerland, WHO, 2021"},{"key":"e_1_3_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(21)00351-X"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.61.9767"},{"key":"e_1_3_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32513-8"}],"container-title":["JCO Global Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/GO-25-00663","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T19:59:24Z","timestamp":1775851164000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/GO-25-00663"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1200\/GO-25-00663"],"URL":"https:\/\/doi.org\/10.1200\/go-25-00663","relation":{},"ISSN":["2687-8941"],"issn-type":[{"value":"2687-8941","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-11-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-15","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2500663"}}