{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:27:03Z","timestamp":1782937623063,"version":"3.54.5"},"reference-count":48,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"7","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Global Oncology"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec><jats:title>PURPOSE<\/jats:title><jats:p> Population-based cancer registries (PBCRs) are critical for national cancer control planning, yet few low- and middle-income countries (LMICs) have quality PBCRs. The Central America Four region represents the principal LMIC region in the Western hemisphere. We describe the establishment of a PBCR in rural Western Honduras with first estimates for the 2013-2017 period. <\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p> The Western Honduras PBCR was established through a collaboration of academic institutions and the Honduras Ministry of Health for collection of incident cancer data from public and private health services. Data were recorded using the Research Electronic Data Capture (REDCap) web-based platform with data monitoring and quality checks. Crude and age-standardized rates (ASRs) were calculated at the regional level, following WHO methodology. <\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p> The web-based platform for data collection, available ancillary data services (eg, endoscopy), and technical support from international centers (United States and Colombia) were instrumental for quality control. Crude cancer incidence rates were 112.2, 69.8, and 154.6 per 100,000 habitants overall, males, and females, respectively (excluding nonmelanoma skin cancer). The adjusted ASRs were 84.2, 49.6, and 118.9 per 100,000 overall habitants, males, and females, respectively. The most common sites among men were stomach (ASR 26.0, 52.4%), colorectal (ASR 5.11, 10.15%), and prostate (ASR 2.7, 5.4%). The most common sites in women were cervix (ASR 34.2, 36.7%), breast (ASR 11.2, 12.3%), and stomach (ASR 10.8, 11.7%). <\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p> The Cop\u00e1n-PBCR represents a successful model to develop cancer monitoring in rural LMICs. Innovations included the use of the REDCap platform and leverage of Health Ministry resources. This provides the first PBCR data for Honduras and the Central America Four and confirms that infection-driven cancers, such as gastric and cervical, should be priority targets for cancer control initiatives. <\/jats:p><\/jats:sec>","DOI":"10.1200\/go.21.00273","type":"journal-article","created":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T21:00:07Z","timestamp":1639688407000},"page":"1694-1702","update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":15,"title":["Western Honduras Cop\u00e1n Population\u2013Based Cancer Registry: Initial Estimates and a Model for Rural Central America"],"prefix":"10.1200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5408-560X","authenticated-orcid":false,"given":"Dalton Argean","family":"Norwood","sequence":"first","affiliation":[{"name":"Western Honduras Gastric Cancer Prevention Initiative, Hospital de Occidente, Santa Rosa de Cop\u00e1n, Honduras"},{"name":"Universidad Nacional Aut\u00f3noma de Honduras, School of Medicine, Honduras"},{"name":"School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7178-0724","authenticated-orcid":false,"given":"Eleazar Enrique","family":"Montalvan-Sanchez","sequence":"additional","affiliation":[{"name":"Western Honduras Gastric Cancer Prevention Initiative, Hospital de Occidente, Santa Rosa de Cop\u00e1n, Honduras"},{"name":"Indiana University, Department of Medicine, Indianapolis, IN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8821-4534","authenticated-orcid":false,"given":"Juan E.","family":"Corral","sequence":"additional","affiliation":[{"name":"Division of Gatroenterology and Hepatology, Presbyterian Healthcare Services, Albuquerque, New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8876-1044","authenticated-orcid":false,"given":"Dagoberto","family":"Est\u00e9vez-Ordo\u00f1ez","sequence":"additional","affiliation":[{"name":"School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6674-369X","authenticated-orcid":false,"given":"Andrea A.","family":"Paredes","sequence":"additional","affiliation":[{"name":"Western Honduras Gastric Cancer Prevention Initiative, Hospital de Occidente, Santa Rosa de Cop\u00e1n, Honduras"},{"name":"Universidad Nacional Aut\u00f3noma de Honduras, School of Medicine, Honduras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7500-7758","authenticated-orcid":false,"given":"Lucia B.","family":"Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Western Honduras Gastric Cancer Prevention Initiative, Hospital de Occidente, Santa Rosa de Cop\u00e1n, Honduras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7553-8401","authenticated-orcid":false,"given":"Aida A.","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Western Honduras Gastric Cancer Prevention Initiative, Hospital de Occidente, Santa Rosa de Cop\u00e1n, Honduras"},{"name":"Universidad Nacional Aut\u00f3noma de Honduras, School of Medicine, Honduras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9708-0312","authenticated-orcid":false,"given":"Luis E.","family":"Bravo","sequence":"additional","affiliation":[{"name":"IACR Regional Representative for Latin America, International Agency for Research on Cancer, Lyon, France"},{"name":"Departamento de Patolog\u00eda, Universidad del Valle, Cali, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1136-0963","authenticated-orcid":false,"given":"Douglas R.","family":"Morgan","sequence":"additional","affiliation":[{"name":"School of Medicine, The University of Alabama at Birmingham, Birmingham, AL"},{"name":"Division of Gastroenterology, Hepatology and Nutrition, The University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo L.","family":"Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Western Honduras Gastric Cancer Prevention Initiative, Hospital de Occidente, Santa Rosa de Cop\u00e1n, Honduras"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","reference":[{"key":"b1","first-page":"7","volume":"95","author":"Jensen OM","year":"1991","journal-title":"IARC Sci Publ"},{"key":"b2","volume-title":"Cancer Epidemiology: Principles and Methods","author":"International Agency for Research on Cancer\u2014World Health Organization"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70028-7"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.11.032"},{"key":"b5","volume-title":"Comparability and Quality Control in Cancer Registration\u2014International Agency for Research on Cancer. IARC Technical Report No.19","author":"Parkin D","year":"1994"},{"key":"b6","volume-title":"Standards for Cancer Registries Volume III: Standards for Completeness, Quality, Analysis, Management, Security and Confidentiality of Data","author":"Hofferkamp J","year":"2008"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22566"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.11.033"},{"key":"b9","volume-title":"Global Action Plan for the Prevention and Control of NCDs 2013-2020","author":"World Health Organization","year":"2013"},{"key":"b10","volume-title":"Cancer Incidence in Five Continents","author":"Bray F","year":"2017"},{"key":"b11","volume-title":"Global Status Report on Noncommunicable Diseases 2014","author":"World Health Organization","year":"2014"},{"key":"b12","volume-title":"Press Release No. 263 Latest Global Cancer Data: Cancer Burden Rises to 18.1 Million New Cases and 9.6 Million Cancer Deaths in 2018","author":"International Agency for Research on Cancer\u2014World Health Organization","year":"2018"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"b14","first-page":"1","volume":"4","author":"Pi\u00f1eros M","year":"2018","journal-title":"JCO Glob Oncol"},{"key":"b15","volume-title":"Bernardo del Valle. Registro Poblacional de Cancer","author":"Instituto de Cancerologia y Hospital Dr"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-012-0109-5"},{"key":"b17","doi-asserted-by":"publisher","DOI":"10.1200\/JGO.2016.003848"},{"key":"b18","doi-asserted-by":"crossref","DOI":"10.1158\/1055-9965.EPI-18-0934","volume":"27","author":"Kennedy LS","year":"2018","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"b19","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29210"},{"key":"b20","volume-title":"Cancer Incidence in Five Continents, Volume X. IARC. Scientific Publication No. 164","author":"Forman D","year":"2014"},{"key":"b21","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-014-9672-1"},{"key":"b22","volume-title":"GLOBOCAN 2012, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 11","author":"Ferlay J","year":"2013"},{"key":"b23","volume-title":"Cancer in Central and South America","author":"Sierra M","year":"2016"},{"key":"b24","volume-title":"Cancer Registration: Principles and Methods","volume":"95","author":"Jensen O","year":"1991"},{"key":"b25","volume-title":"Censo de Pobacion XVII y Vivienda VI","author":"Instituto Nacional de Estadistica","year":"2013"},{"key":"b26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-0009.2005.00398.x"},{"key":"b27","volume-title":"Planning and Developing Population-Based Cancer Registration in Low- and Middle-Income Settings IARC Technical Publication No. 43","author":"Bray F","year":"2014"},{"key":"b28","volume-title":"International Classification of Diseases 10th Revision in: World Health Organization","author":"World Health Organization","year":"2010"},{"key":"b29","volume-title":"International Classification of Diseases for Oncology","author":"Fritz A","year":"2013","edition":"4"},{"key":"b30","unstructured":"Pan American Health Organization: Programas nacionales de control del c\u00e1ncer: Pol\u00edticas y pautas para la gesti\u00f3n. Washington, DC, World Health Organization, 2004, pp 219"},{"key":"b31","doi-asserted-by":"publisher","DOI":"10.4054\/DemRes.2002.7.5"},{"key":"b32","doi-asserted-by":"publisher","DOI":"10.1596\/978-1-4648-0349-9_ch2"},{"key":"b33","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-009-9414-z"},{"key":"b34","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.1622"},{"key":"b35","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-19-0790"},{"key":"b36","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.05.025"},{"key":"b37","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-012-0114-8"},{"key":"b38","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdi086"},{"key":"b39","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2016.03.010"},{"key":"b40","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20038"},{"key":"b41","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2018.01.008"},{"key":"b42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2018.09.021"},{"key":"b43","volume-title":"Honduras Contry Profile\u2014Latin America & Caribbean","author":"The World Bank"},{"key":"b44","first-page":"1","volume":"4","author":"Frech S","year":"2018","journal-title":"JCO Glob Oncol"},{"key":"b45","author":"IARC G","journal-title":"Latin America Hub"},{"key":"b46","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2005.07.021"},{"key":"b47","first-page":"1","volume":"4","author":"de Vries E","year":"2018","journal-title":"JCO Glob Oncol"},{"key":"b48","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009823"}],"container-title":["JCO Global Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/GO.21.00273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T08:07:21Z","timestamp":1653811641000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/GO.21.00273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":48,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1200\/GO.21.00273"],"URL":"https:\/\/doi.org\/10.1200\/go.21.00273","relation":{},"ISSN":["2687-8941"],"issn-type":[{"value":"2687-8941","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"2021-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-21","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}