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Living guidelines are updated on a regular schedule by a standing expert panel that systematically reviews the health literature on a continuous basis, as described in the<\/jats:italic>\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/asco.org\/guideline-methodology\">\n              <jats:italic>ASCO Guidelines Methodology Manual<\/jats:italic>\n            <\/jats:ext-link>\n            .\n            <jats:italic>ASCO Living Guidelines follow the<\/jats:italic>\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/asco.org\/rwc\">\n              <jats:italic>ASCO Conflict of Interest Policy Implementation for Clinical Practice Guidelines<\/jats:italic>\n            <\/jats:ext-link>\n            .\n            <jats:italic>\n              Living Guidelines and updates are not intended to substitute for independent professional judgment of the treating clinician and do not account for individual variation among patients. See the Appendix for disclaimers and other important information (\n              <jats:xref ref-type=\"app\">Appendix 1<\/jats:xref>\n              and\n              <jats:xref ref-type=\"app\">Appendix 2<\/jats:xref>\n            <\/jats:italic>\n            ,\n            <jats:italic>online only). 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