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The details of the PMRT technique were also evaluated.<\/jats:p>\n                  <jats:p>OUTCOMES: The outcomes considered included freedom from local-regional recurrence, survival (disease-free and overall), and long-term toxicity.<\/jats:p>\n                  <jats:p>EVIDENCE: An expert multidisciplinary panel reviewed pertinent information from the published literature through July 2000; certain investigators were contacted for more recent and, in some cases, unpublished information. A computerized search was performed of MEDLINE data; directed searches based on the bibliographies of primary articles were also performed.<\/jats:p>\n                  <jats:p>VALUES: Levels of evidence and guideline grades were assigned by the Panel using standard criteria. A \u201crecommendation\u201d was made when level I or II evidence was available and there was consensus as to its meaning. A \u201csuggestion\u201d was made based on level III, IV, or V evidence and there was consensus as to its meaning. Areas of clinical importance were pointed out where guidelines could not be formulated due to insufficient evidence or lack of consensus.<\/jats:p>\n                  <jats:p>RECOMMENDATIONS: The recommendations, suggestions, and expert opinions of the Panel are described in this article.<\/jats:p>\n                  <jats:p>VALIDATION: Seven outside reviewers, the American Society of Clinical Oncology (ASCO) Health Services Research Committee members, and the ASCO Board of Directors reviewed this document.<\/jats:p>","DOI":"10.1200\/jco.2001.19.5.1539","type":"journal-article","created":{"date-parts":[[2017,2,24]],"date-time":"2017-02-24T03:08:14Z","timestamp":1487905694000},"page":"1539-1569","source":"Crossref","is-referenced-by-count":685,"title":["Postmastectomy Radiotherapy: Clinical Practice Guidelines of the American Society of Clinical Oncology*"],"prefix":"10.1200","volume":"19","author":[{"given":"Abram","family":"Recht","sequence":"first","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen B.","family":"Edge","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence J.","family":"Solin","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Robinson","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Estabrook","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Fine","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gini F.","family":"Fleming","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Formenti","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clifford","family":"Hudis","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey J.","family":"Kirshner","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Krause","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert R.","family":"Kuske","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy S.","family":"Langer","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"George W.","family":"Sledge","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Whelan","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"Pfister","sequence":"additional","affiliation":[{"name":"From the American Society of Clinical Oncology, Alexandria, VA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","reference":[{"key":"R1-086762","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1994.12.3.447"},{"key":"R2-086762","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199511303332202"},{"key":"R3-086762","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02263-7"},{"key":"R4-086762","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1995.13.12.2861"},{"key":"R6-086762","unstructured":"Pierce  LJ,   Lichter  AS:   Defining the role of post-mastectomy radiotherapy:   the new evidence.   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