{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:07:54Z","timestamp":1763035674612},"reference-count":26,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCO"],"published-print":{"date-parts":[[2002,5,15]]},"abstract":"<jats:p> PURPOSE: The purpose of this study was to evaluate voice rehabilitation after laryngectomy and postoperative irradiation for patients with squamous cell carcinoma of the larynx and hypopharynx. <\/jats:p><jats:p> PATIENTS AND METHODS: Between December 1983 and December 1998, 173 patients underwent a total laryngectomy and postoperative irradiation and had follow-up from 3 to 188 months (median, 38 months). Three patients were lost to follow-up at 63, 39, and 4 months after treatment. All other living patients had follow-up for 2 years or longer. Twelve (7%) patients had incomplete data pertaining to voice rehabilitation. <\/jats:p><jats:p> RESULTS: Data pertaining to voice rehabilitation were available at 2 to 3 years and longer and 5 years and longer after treatment for 118 and 69 patients, respectively. The methods of voice rehabilitation at 2 to 3 years and longer and 5 years and longer were as follows: tracheoesophageal, 27% and 19%; artificial larynx, 50% and 57%; esophageal, 1% and 3%; nonvocal, 17% and 14%; and no data, 5% and 7%, respectively. <\/jats:p><jats:p> CONCLUSION: The most common form of voice rehabilitation after total laryngectomy and postoperative radiation therapy is the artificial larynx. Although the tracheoesophageal puncture is a technique frequently promoted by clinicians as a superior method, a relatively small subset of patients are successfully rehabilitated long-term. However, of those who undergo a tracheoesophageal puncture, approximately half will use this method of voice rehabilitation long term. <\/jats:p>","DOI":"10.1200\/jco.2002.07.047","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:13:48Z","timestamp":1027775628000},"page":"2500-2505","source":"Crossref","is-referenced-by-count":47,"title":["Voice Rehabilitation After Total Laryngectomy and Postoperative Radiation Therapy"],"prefix":"10.1200","volume":"20","author":[{"given":"William M.","family":"Mendenhall","sequence":"first","affiliation":[{"name":"From the Departments of Radiation Oncology and Otolaryngology, University of Florida College of Medicine, Gainesville, FL."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher G.","family":"Morris","sequence":"additional","affiliation":[{"name":"From the Departments of Radiation Oncology and Otolaryngology, University of Florida College of Medicine, Gainesville, FL."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott P.","family":"Stringer","sequence":"additional","affiliation":[{"name":"From the Departments of Radiation Oncology and Otolaryngology, University of Florida College of Medicine, Gainesville, FL."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Amdur","sequence":"additional","affiliation":[{"name":"From the Departments of Radiation Oncology and Otolaryngology, University of Florida College of Medicine, Gainesville, FL."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell W.","family":"Hinerman","sequence":"additional","affiliation":[{"name":"From the Departments of Radiation Oncology and Otolaryngology, University of Florida College of Medicine, Gainesville, FL."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas B.","family":"Villaret","sequence":"additional","affiliation":[{"name":"From the Departments of Radiation Oncology and Otolaryngology, University of Florida College of Medicine, Gainesville, FL."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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