{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:52:08Z","timestamp":1775148728848,"version":"3.50.1"},"reference-count":46,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCO"],"published-print":{"date-parts":[[2005,2,20]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>In 1993, a randomized intervention study among patients with malignant melanoma showed a significant decrease in psychological distress and increased coping capacity 6 months after the intervention and enhanced survival 6 years later. We applied a similar intervention with a few modifications in a randomized controlled trial among Danish patients with malignant melanoma and evaluated results on immediate and long-term effects on psychological distress and coping capacity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>A total of 262 patients with primary cutaneous malignant melanoma were randomly assigned to the control or intervention group. Patients in the intervention group were offered six weekly sessions of 2 hours of psychoeducation, consisting of health education, enhancement of problem-solving skills, stress management, and psychological support. The participants were assessed at baseline before random assignment and 6 and 12 months after surgery. The analyses of the main effects of the intervention were based on analyses of covariance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patients in the intervention group showed significantly less fatigue, greater vigor, and lower total mood disturbance compared with the controls, and they used significantly more active-behavioral and active-cognitive coping than the patients in the control group. The improvements were only significant at first follow-up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings of this study support the results of an earlier intervention study among patients with malignant melanoma and indicate that a psychoeducational group intervention for such patients can decrease psychological distress and enhance effective coping. However, this effect is short term and the clinical relevance is not obvious.<\/jats:p><\/jats:sec>","DOI":"10.1200\/jco.2005.05.193","type":"journal-article","created":{"date-parts":[[2005,2,18]],"date-time":"2005-02-18T00:38:54Z","timestamp":1108687134000},"page":"1270-1277","source":"Crossref","is-referenced-by-count":99,"title":["Psychoeducational Intervention for Patients With Cutaneous Malignant Melanoma: A Replication Study"],"prefix":"10.1200","volume":"23","author":[{"given":"Ellen H.","family":"Boesen","sequence":"first","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lone","family":"Ross","sequence":"additional","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten","family":"Frederiksen","sequence":"additional","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birthe L.","family":"Thomsen","sequence":"additional","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Dahlstr\u00f8m","sequence":"additional","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grethe","family":"Schmidt","sequence":"additional","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesper","family":"N\u00e6sted","sequence":"additional","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christen","family":"Krag","sequence":"additional","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoffer","family":"Johansen","sequence":"additional","affiliation":[{"name":"From the Institute of Cancer Epidemiology, Danish Cancer Society; Department of Plastic Surgery and Burn Unit, Rigshospitalet, University of Copenhagen, Copenhagen; Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Copenhagen County; and Department of Plastic and Reconstructive Surgery, Roskilde University Hospital, Roskilde, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"233","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(02)00126-0"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)91551-1"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1993.01820210015002"},{"key":"R4","unstructured":"Kuchler T, Henne-Bruns D, Rappat S, et al: Impact of psychotherapeutic support on gastrointestinal cancer patients undergoing surgery: Survival results of a trial. Hepatogastroenterology 46:322,1999\u2013335,"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2000.tb03886.x"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.1.100"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011871"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.58.5.494"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.19.2.107"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.60.4.552"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1002\/pon.683"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1016\/0163-8343(94)90098-1"},{"key":"R13","doi-asserted-by":"crossref","unstructured":"Johnson J: The effects of a patient education course on persons with a chronic illness. Cancer Nurs 2:117,1982\u2013123,","DOI":"10.1097\/00002820-198204000-00003"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.304.6828.675"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860101)57:1<183::AID-CNCR2820570135>3.0.CO;2-3"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1002\/pon.2960020108"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(96)00134-7"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1611(199907\/08)8:4<295::AID-PON386>3.0.CO;2-Y"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.59.4.518"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1611(199805\/06)7:3<207::AID-PON304>3.0.CO;2-T"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1097\/00002820-198908000-00006"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.2466\/pr0.1986.59.2.967"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1016\/0277-5379(91)90480-2"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-200009000-00004"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1300\/J077v16n03_02"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1002\/1099-1611(200101\/02)10:1<1::AID-PON484>3.0.CO;2-T"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-4560.1991.tb01836.x"},{"key":"R28","doi-asserted-by":"crossref","unstructured":"Lev EL: Bandura's theory of self-efficacy: Applications to oncology. Sch Inq Nurs Pract 11:21,1997\u201337,","DOI":"10.1891\/0889-7182.11.1.21"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.22.2.210"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1990.01810200028004"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1559-1816.1987.tb00316.x"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.16.3635"},{"key":"R33","unstructured":"McNair DM, Lorr M, Droppleman LF: EdiTS manual for the Profile of Mood States . Manual for the Profile of Mood States, 3-29. San Diego, CA, Educational and Industrial Testing Service, 1992"},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1611(199811\/12)7:6<508::AID-PON376>3.0.CO;2-7"},{"key":"R35","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1611(199911\/12)8:6<474::AID-PON427>3.0.CO;2-A"},{"key":"R36","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20000901)89:5<1026::AID-CNCR12>3.0.CO;2-5"},{"key":"R37","doi-asserted-by":"publisher","DOI":"10.1097\/00002820-199512000-00002"},{"key":"R38","unstructured":"Kjoeller M, Rasmussen NK, Keiding L, et al: Health and Morbidity in Denmark 1994 . Copenhagen, Denmark, Danish Institute for Clinical Epidemiologi, pp 9,1995\u2013335"},{"key":"R39","unstructured":"Bandura A: Self-Efficacy: The Exercise of Control . New York, NY, W.H. Freeman, 1997"},{"key":"R40","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1611(200003\/04)9:2<169::AID-PON441>3.0.CO;2-V"},{"key":"R41","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(97)71503-2"},{"key":"R42","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1995.03950140018003"},{"key":"R43","doi-asserted-by":"publisher","DOI":"10.1300\/J077v03n03_08"},{"key":"R44","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.54.6.802"},{"key":"R45","unstructured":"Evans RL, Connis RT: Comparison of brief group therapies for depressed cancer patients receiving radiation treatment. Public Health Rep 110:306,1995\u2013311,"},{"key":"R46","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1611(199606)5:2<127::AID-PON220>3.0.CO;2-L"}],"container-title":["Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/JCO.2005.05.193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T11:53:27Z","timestamp":1734954807000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/JCO.2005.05.193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,20]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,2,20]]}},"alternative-id":["10.1200\/JCO.2005.05.193"],"URL":"https:\/\/doi.org\/10.1200\/jco.2005.05.193","relation":{},"ISSN":["0732-183X","1527-7755"],"issn-type":[{"value":"0732-183X","type":"print"},{"value":"1527-7755","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,20]]}}}