{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:56:24Z","timestamp":1791420984809,"version":"4.3.3"},"reference-count":29,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"33","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO"],"published-print":{"date-parts":[[2016,11,20]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p> To assess melanoma risk in relation to sunscreen use and to compare high\u2013 with low\u2013sun protection factor (SPF) sunscreens in relation to sunbathing habits in a large cohort study. <\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p> We used data from the Norwegian Women and Cancer Study, a prospective population-based study of 143,844 women age 40 to 75 years at inclusion with 1,532,247 person-years of follow-up and 722 cases of melanoma. Multivariable Cox proportional hazards regression was used to estimate the association between sunscreen use (never, SPF &lt; 15, SPF \u2265 15) and melanoma risk by calculating hazard ratios and 95% CIs. The population attributable fraction associated with sunscreen use was estimated. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Sunscreen users reported significantly more sunburns and sunbathing vacations and were more likely to use indoor tanning devices. SPF \u2265 15 sunscreen use was associated with significantly decreased melanoma risk compared with SPF &lt; 15 use (hazard ratio, 0.67; 95% CI, 0.53 to 0.83). The estimated decrease in melanoma (population attributable fraction) with general use of SPF \u2265 15 sunscreens by women age 40 to 75 years was 18% (95% CI, 4% to 30%). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Use of SPF \u2265 15 rather than SPF &lt; 15 sunscreens reduces melanoma risk. Moreover, use of SPF \u2265 15 sunscreen by all women age 40 to 75 years could potentially reduce their melanoma incidence by 18%. <\/jats:p><\/jats:sec>","DOI":"10.1200\/jco.2016.67.5934","type":"journal-article","created":{"date-parts":[[2016,9,13]],"date-time":"2016-09-13T02:29:21Z","timestamp":1473733761000},"page":"3976-3983","update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":97,"title":["Sunscreen Use and Subsequent Melanoma Risk: A Population-Based Cohort Study"],"prefix":"10.1200","volume":"34","author":[{"given":"Reza","family":"Ghiasvand","sequence":"first","affiliation":[{"name":"Reza Ghiasvand and Marit B. Veier\u00f8d, Institute of Basic Medical Sciences, University of Oslo; Elisabete Weiderpass, Cancer Registry of Norway, Oslo; Elisabete Weiderpass and Eiliv Lund, University of Troms\u00f8\u2013The Arctic University of Norway, Troms\u00f8, Norway; Elisabete Weiderpass, Karolinska Institutet, Stockholm, Sweden; Elisabete Weiderpass, Folkh\u00e4lsan Research Center, Helsinki, Finland; Adele C. Green, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; and Adele C. Green,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabete","family":"Weiderpass","sequence":"additional","affiliation":[{"name":"Reza Ghiasvand and Marit B. Veier\u00f8d, Institute of Basic Medical Sciences, University of Oslo; Elisabete Weiderpass, Cancer Registry of Norway, Oslo; Elisabete Weiderpass and Eiliv Lund, University of Troms\u00f8\u2013The Arctic University of Norway, Troms\u00f8, Norway; Elisabete Weiderpass, Karolinska Institutet, Stockholm, Sweden; Elisabete Weiderpass, Folkh\u00e4lsan Research Center, Helsinki, Finland; Adele C. Green, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; and Adele C. Green,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adele C.","family":"Green","sequence":"additional","affiliation":[{"name":"Reza Ghiasvand and Marit B. Veier\u00f8d, Institute of Basic Medical Sciences, University of Oslo; Elisabete Weiderpass, Cancer Registry of Norway, Oslo; Elisabete Weiderpass and Eiliv Lund, University of Troms\u00f8\u2013The Arctic University of Norway, Troms\u00f8, Norway; Elisabete Weiderpass, Karolinska Institutet, Stockholm, Sweden; Elisabete Weiderpass, Folkh\u00e4lsan Research Center, Helsinki, Finland; Adele C. Green, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; and Adele C. Green,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiliv","family":"Lund","sequence":"additional","affiliation":[{"name":"Reza Ghiasvand and Marit B. Veier\u00f8d, Institute of Basic Medical Sciences, University of Oslo; Elisabete Weiderpass, Cancer Registry of Norway, Oslo; Elisabete Weiderpass and Eiliv Lund, University of Troms\u00f8\u2013The Arctic University of Norway, Troms\u00f8, Norway; Elisabete Weiderpass, Karolinska Institutet, Stockholm, Sweden; Elisabete Weiderpass, Folkh\u00e4lsan Research Center, Helsinki, Finland; Adele C. Green, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; and Adele C. Green,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marit B.","family":"Veier\u00f8d","sequence":"additional","affiliation":[{"name":"Reza Ghiasvand and Marit B. Veier\u00f8d, Institute of Basic Medical Sciences, University of Oslo; Elisabete Weiderpass, Cancer Registry of Norway, Oslo; Elisabete Weiderpass and Eiliv Lund, University of Troms\u00f8\u2013The Arctic University of Norway, Troms\u00f8, Norway; Elisabete Weiderpass, Karolinska Institutet, Stockholm, Sweden; Elisabete Weiderpass, Folkh\u00e4lsan Research Center, Helsinki, Finland; Adele C. Green, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; and Adele C. 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