{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:47:08Z","timestamp":1787773628513,"version":"build-2784847793"},"reference-count":23,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"4","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JGO"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p> There is a dearth of data on clearance of cervical human papillomavirus (HPV) infection among women in West Africa. We examined the clearance of low-risk (lr) and high-risk (hr) cervical HPV infections, and the factors associated with these measures in HIV-negative and HIV-positive women. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> We studied 630 Nigerian women involved in a study of HPV infection using short polymerase chain reaction fragment-10 assay and line probe assay-25. Research nurses used a cervical brush to collect samples of exfoliated cervical cells from all the study participants. Cox proportional hazards models were used to estimate associations between HIV and HPV infections. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> The mean age of the study participants was 38 (standard deviation, \u00b1 8) years; 51% were HIV positive. The rate of clearing any HPV infection was 2.0% per month among all women in the study population, 2.5% per month among HIV-negative women, and 1.6% per month, among HIV-positive women. The clearance rate per 1,000 person-months of observation for any lrHPV infection and any hrHPV infection were 9.21 and 8.83, respectively, for HIV-negative women, and 9.38 and 9.37, respectively, for HIV-positive women. In multivariate models, the hazard ratios for HIV-positive compared with HIV-negative women were 0.85 (95% CI, 0.51 to 1.43; P = .55) and 0.95 (95% CI, 0.54 to 1.65; P = .85) for cleared infections with any lrHPV and any hrHPV, respectively. The hazard ratio for HIV-positive compared with HIV-negative women was 0.39 (95% CI, 0.17 to 0.88; P = .02) for cleared infections with any multiple HPV and 0.13 (95% CI, 0.03 to 0.58; P = .007) for cleared infections with multiple hrHPV. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> In this study population, we observed that HIV-positive women were less likely to clear infections with multiple hrHPV types. <\/jats:p><\/jats:sec>","DOI":"10.1200\/jgo.17.00129","type":"journal-article","created":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T20:00:29Z","timestamp":1534795229000},"update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":8,"title":["Clearance of Type-Specific, Low-Risk, and High-Risk Cervical Human Papillomavirus Infections in HIV-Negative and HIV-Positive Women"],"prefix":"10.1200","author":[{"given":"Sally N.","family":"Adebamowo","sequence":"first","affiliation":[{"name":"Sally N. Adebamowo and Clement A. Adebamowo, University of Maryland School of Medicine, Baltimore, MD; Sally N. Adebamowo, Ayotunde Famooto, and Clement A. Adebamowo, Center for Bioethics and Research, Ibadan; Ayotunde Famooto and Oluwatoyosi Olawande, Institute of Human Virology Nigeria; Olayinka Olaniyan, National Hospital Abuja; Richard Offiong, University of Abuja Teaching Hospital, Abuja, Nigeria; Eileen O. Dareng, University of Cambridge, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayotunde","family":"Famooto","sequence":"additional","affiliation":[{"name":"Sally N. Adebamowo and Clement A. Adebamowo, University of Maryland School of Medicine, Baltimore, MD; Sally N. Adebamowo, Ayotunde Famooto, and Clement A. Adebamowo, Center for Bioethics and Research, Ibadan; Ayotunde Famooto and Oluwatoyosi Olawande, Institute of Human Virology Nigeria; Olayinka Olaniyan, National Hospital Abuja; Richard Offiong, University of Abuja Teaching Hospital, Abuja, Nigeria; Eileen O. Dareng, University of Cambridge, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen O.","family":"Dareng","sequence":"additional","affiliation":[{"name":"Sally N. Adebamowo and Clement A. Adebamowo, University of Maryland School of Medicine, Baltimore, MD; Sally N. Adebamowo, Ayotunde Famooto, and Clement A. Adebamowo, Center for Bioethics and Research, Ibadan; Ayotunde Famooto and Oluwatoyosi Olawande, Institute of Human Virology Nigeria; Olayinka Olaniyan, National Hospital Abuja; Richard Offiong, University of Abuja Teaching Hospital, Abuja, Nigeria; Eileen O. Dareng, University of Cambridge, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluwatoyosi","family":"Olawande","sequence":"additional","affiliation":[{"name":"Sally N. Adebamowo and Clement A. Adebamowo, University of Maryland School of Medicine, Baltimore, MD; Sally N. Adebamowo, Ayotunde Famooto, and Clement A. Adebamowo, Center for Bioethics and Research, Ibadan; Ayotunde Famooto and Oluwatoyosi Olawande, Institute of Human Virology Nigeria; Olayinka Olaniyan, National Hospital Abuja; Richard Offiong, University of Abuja Teaching Hospital, Abuja, Nigeria; Eileen O. Dareng, University of Cambridge, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olayinka","family":"Olaniyan","sequence":"additional","affiliation":[{"name":"Sally N. Adebamowo and Clement A. Adebamowo, University of Maryland School of Medicine, Baltimore, MD; Sally N. Adebamowo, Ayotunde Famooto, and Clement A. Adebamowo, Center for Bioethics and Research, Ibadan; Ayotunde Famooto and Oluwatoyosi Olawande, Institute of Human Virology Nigeria; Olayinka Olaniyan, National Hospital Abuja; Richard Offiong, University of Abuja Teaching Hospital, Abuja, Nigeria; Eileen O. Dareng, University of Cambridge, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Offiong","sequence":"additional","affiliation":[{"name":"Sally N. Adebamowo and Clement A. Adebamowo, University of Maryland School of Medicine, Baltimore, MD; Sally N. Adebamowo, Ayotunde Famooto, and Clement A. Adebamowo, Center for Bioethics and Research, Ibadan; Ayotunde Famooto and Oluwatoyosi Olawande, Institute of Human Virology Nigeria; Olayinka Olaniyan, National Hospital Abuja; Richard Offiong, University of Abuja Teaching Hospital, Abuja, Nigeria; Eileen O. Dareng, University of Cambridge, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clement A.","family":"Adebamowo","sequence":"additional","affiliation":[{"name":"Sally N. Adebamowo and Clement A. Adebamowo, University of Maryland School of Medicine, Baltimore, MD; Sally N. Adebamowo, Ayotunde Famooto, and Clement A. Adebamowo, Center for Bioethics and Research, Ibadan; Ayotunde Famooto and Oluwatoyosi Olawande, Institute of Human Virology Nigeria; Olayinka Olaniyan, National Hospital Abuja; Richard Offiong, University of Abuja Teaching Hospital, Abuja, Nigeria; Eileen O. Dareng, University of Cambridge, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the ACCME Research Group as part of the H3Africa Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","reference":[{"key":"B1","volume-title":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: Biological Agents, A Review of Human Carcinogenesis","year":"2012"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.05.026"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70190-0"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1186\/1750-9378-5-19"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066930"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00517-06"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.8.2508-2517.1999"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65462-4"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1086\/520883"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3758\/BF03193146"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3758\/BRM.41.4.1149"},{"key":"B12","first-page":"115","volume":"38","author":"Filmer D","year":"2001","journal-title":"Demography"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000272"},{"key":"B14","first-page":"421","volume":"168","author":"Sellors JW","year":"2003","journal-title":"CMAJ"},{"key":"B15","first-page":"503","volume":"163","author":"Sellors JW","year":"2000","journal-title":"CMAJ"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2016.10.013"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1186\/1750-9378-5-7"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22015"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001113"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/95.14.1062"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0013525"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.09.086"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.154.2.127"}],"container-title":["Journal of Global Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/JGO.17.00129","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T07:03:38Z","timestamp":1653807818000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/JGO.17.00129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1200\/JGO.17.00129"],"URL":"https:\/\/doi.org\/10.1200\/jgo.17.00129","relation":{},"ISSN":["2378-9506"],"issn-type":[{"value":"2378-9506","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"2018-08-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"JGO.17.00129"}}