{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T19:44:25Z","timestamp":1765827865761},"reference-count":30,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"6","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Global Oncology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:title>PURPOSE<\/jats:title><jats:p>Colorectal cancer (CRC) is a disease of public health importance because of the increasing incidence of the disease and presentation in advanced stage of the disease in Western Africa. CRC is amenable to screening because of the long course of premalignant lesions before final development of the disease. Despite this, the practice of CRC screening is inadequate at the sites in this study. The fecal immunochemical test (FIT) is one of the recommended noninvasive methods for CRC screening. It has a sensitivity of 96%, specificity of 90%, and an overall accuracy of 95%. We aimed to determine the practicability of FIT for CRC screening in patients aged 40 to 75 years who attended primary care clinics in the University College Hospital, Ibadan, Nigeria.<\/jats:p><\/jats:sec><jats:sec><jats:title>PATIENTS AND METHODS<\/jats:title><jats:p>A total of 422 patients selected by systematic random sampling were recruited and offered free FIT screening. Participants with a positive finding had additional GI examination, including a digital rectal examination, proctoscopy, and colonoscopy, if no lesion was biopsied during proctoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The mean (\u00b1 standard deviation) age of the respondents was 62 \u00b1 9.61 years. The prevalence of a positive FIT in the study was 10.1%. The FIT was not completed by 3.8% of patients, and the rate of completion of additional evaluation after a positive FIT reduced as the investigations became invasive, with 36.8% and 71.1% noncompletion rates for proctoscopy and colonoscopy, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>A FIT-based screening for age and risk-appropriate patients is practical in this environment, where the capacity and acceptability of colonoscopy are limited.<\/jats:p><\/jats:sec>","DOI":"10.1200\/jgo.19.00340","type":"journal-article","created":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T20:13:30Z","timestamp":1585340010000},"page":"525-531","update-policy":"http:\/\/dx.doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":5,"title":["Fecal Immunochemical Test as a Screening Method for Colorectal Cancer in University College Hospital Ibadan, Nigeria"],"prefix":"10.1200","author":[{"given":"Elizabeth O.","family":"Labaeka","sequence":"first","affiliation":[{"name":"Department of Family Medicine University, College Hospital Ibadan, Ibadan, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achiaka E.","family":"Irabor","sequence":"additional","affiliation":[{"name":"Department of Family Medicine University, College Hospital Ibadan, Ibadan, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David O.","family":"Irabor","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Gastrointestinal Surgery, University College Hospital Ibadan, Ibadan, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"233","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20038"},{"key":"B2","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1111\/j.1572-0241.2008.01875.x","volume":"103","author":"Hewitson P","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.101248"},{"key":"B5","first-page":"112","volume":"69","author":"de Wijkerslooth TR","year":"2011","journal-title":"Neth J Med"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.03.040"},{"key":"B7","first-page":"95","volume":"126","author":"Hsiang JC","year":"2013","journal-title":"N Z Med J"},{"key":"B8","doi-asserted-by":"crossref","first-page":"e231","DOI":"10.3399\/bjgp11X572427","volume":"61","author":"Astin M","year":"2011","journal-title":"Br J Gen Pract"},{"key":"B9","doi-asserted-by":"crossref","first-page":"627","DOI":"10.7326\/0003-4819-149-9-200811040-00243","volume":"149","author":"Screening for Colorectal Cancer","year":"2008","journal-title":"Ann Intern Med"},{"key":"B10","doi-asserted-by":"crossref","unstructured":"von Karsa L, Patnick J, Segnan N: European guidelines for quality assurance in colorectal cancer screening and diagnosis. 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