{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:26:12Z","timestamp":1764174372162},"reference-count":52,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"11","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JOP"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:p> The 1990s saw an increased use of chemoradiotherapy protocols, commonly referred to as organ-sparing therapy, for the treatment of oropharyngeal cancer after the Groupe d'Oncologie Radioth\u00e9rapie T\u00eate et Cou trial. Since that time, human papillomavirus\u2013associated oropharyngeal squamous cell carcinoma has been identified as a unique disease, with improved survival regardless of treatment modality. The improved outcomes of this population has led to re-evaluation of treatment paradigms in the past decade, with a desire to spare young, human papillomavirus\u2013positive patients the treatment-related toxicities of chemoradiotherapy and to use new minimally invasive surgical techniques to improve outcomes. Numerous retrospective and prospective studies have investigated the role of surgery in treatment of oropharyngeal carcinoma and have demonstrated equivalent oncologic outcomes and improved functional outcomes compared with chemoradiotherapy protocols. Ongoing and future clinical trials may help delineate the role of surgery in the future. <\/jats:p>","DOI":"10.1200\/jop.2016.015263","type":"journal-article","created":{"date-parts":[[2017,2,24]],"date-time":"2017-02-24T10:21:32Z","timestamp":1487931692000},"page":"1176-1183","update-policy":"http:\/\/dx.doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":20,"title":["Current Role of Surgery in the Management of Oropharyngeal Cancer"],"prefix":"10.1200","volume":"12","author":[{"given":"Meghan T.","family":"Turner","sequence":"first","affiliation":[{"name":"University of Pittsburgh Medical Center, Pittsburgh, PA; and Medical College of Georgia at Augusta University, Augusta, GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Kenneth","family":"Byrd","sequence":"additional","affiliation":[{"name":"University of Pittsburgh Medical Center, Pittsburgh, PA; and Medical College of Georgia at Augusta University, Augusta, GA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Ferris","sequence":"additional","affiliation":[{"name":"University of Pittsburgh Medical Center, Pittsburgh, PA; and Medical College of Georgia at Augusta University, Augusta, GA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"233","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198405000-00002"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-188612000-00013"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1991.01870190069014"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1992.01880110032008"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/91.24.2081"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0912217"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2009.04.014"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195309)6:5<963::AID-CNCR2820060515>3.0.CO;2-Q"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814538605"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.20740"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.36.4596"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djn011"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.50.3870"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.8841"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1177\/000348941011900605"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.55.1937"},{"key":"b17","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-2335-6"},{"key":"b18","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-2097-1"},{"key":"b19","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21669"},{"key":"b20","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20552"},{"key":"b21","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200307000-00008"},{"key":"b22","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000199899.00479.75"},{"key":"b23","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2012.1166"},{"key":"b24","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000227184.90514.1a"},{"key":"b25","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814525746"},{"key":"b26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2015.02.002"},{"key":"b27","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24101"},{"key":"b28","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.185"},{"key":"b29","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.1508"},{"key":"b30","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24456"},{"key":"b31","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24712"},{"key":"b32","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23995"},{"key":"b33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.04.011"},{"key":"b34","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-2985-7"},{"key":"b35","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.3228"},{"key":"b36","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23385"},{"key":"b37","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-016-0142-6"},{"key":"b38","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814533494"},{"key":"b39","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2015.10.016"},{"key":"b40","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2013.3866"},{"key":"b41","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-15-0907"},{"key":"b42","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-15-0101"},{"key":"b43","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2016.63"},{"key":"b44","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-13-133"},{"key":"b45","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.62.3157"},{"key":"b46","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28169"},{"key":"b47","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29938"},{"key":"b48","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.26671"},{"key":"b49","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25140"},{"key":"b50","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.0347"},{"key":"b51","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20279"},{"key":"b52","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2016.02.011"}],"container-title":["Journal of Oncology Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/JOP.2016.015263","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T10:51:08Z","timestamp":1653821468000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/JOP.2016.015263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":52,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1200\/JOP.2016.015263"],"URL":"https:\/\/doi.org\/10.1200\/jop.2016.015263","relation":{},"ISSN":["1554-7477","1935-469X"],"issn-type":[{"value":"1554-7477","type":"print"},{"value":"1935-469X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"2016-09-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}