{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:31:43Z","timestamp":1790368303013,"version":"4.1.0"},"reference-count":47,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"5","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Oncol Pract"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>The number of individuals living with advanced and metastatic cancer that is likely incurable is rapidly growing. These individuals, treated with the intent to prolong life and maximize the quality of life, often experience cancer as a chronic disease and undergo treatment with multiple lines of therapy. Because of their experience with cancer as a chronic disease, this subgroup of survivors has unique survivorship challenges and corresponding needs. In recognition of this consideration, the Multinational Association of Supportive Care in Cancer and ASCO published standards and practice recommendations relevant to the delivery of quality survivorship care for this emerging population. As nascent research, clinical, and policy efforts focused on individuals living with advanced and metastatic cancer have expanded, a corresponding need to accurately and consistently define this population has emerged. To date, however, there is a lack of terminological clarity for this emerging survivor subgroup. To address the gap, this article discusses how the lack of clear, consistent definition of individuals living with advanced and metastatic cancer that is likely incurable represents a critical barrier to advancing research and improving clinical care for these individuals. We explore situations in which stage (advanced or metastatic) and treatment intent (curative vs noncurative) diverge. We propose that the essential characteristic that defines this survivor subgroup and differentiates them from individuals in other phases of survivorship is that they undergo noncurative treatment with the goal of prolonging life and improving quality of life, regardless of the anatomic stage. Finally, we discuss emerging strategies to identify individuals living with likely incurable cancer from the electronic health record and cancer registries for the purposes of research and clinical care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1200\/op-25-00872","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T20:59:08Z","timestamp":1764968348000},"page":"735-741","update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":5,"title":["Characterizing Survivors Living With Likely Incurable Cancer: A Closer Look at an Emerging Population"],"prefix":"10.1200","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6605-8045","authenticated-orcid":false,"given":"Shivani","family":"Sharma","sequence":"first","affiliation":[{"name":"Division of Hematology and Medical Oncology, Department of Medicine, Medical University of South Carolina, Charleston, SC"},{"name":"Hollings Cancer Center, Medical University of South Carolina, Charleston, SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7297-9420","authenticated-orcid":true,"given":"Jennifer","family":"Dahne","sequence":"additional","affiliation":[{"name":"Hollings Cancer Center, Medical University of South Carolina, Charleston, SC"},{"name":"Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Gallicchio","sequence":"additional","affiliation":[{"name":"Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8092-3013","authenticated-orcid":true,"given":"Michelle A.","family":"Mollica","sequence":"additional","affiliation":[{"name":"Hollings Cancer Center, Medical University of South Carolina, Charleston, SC"},{"name":"College of Nursing, Medical University of South Carolina, Charleston, SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1185-5210","authenticated-orcid":true,"given":"Emily","family":"Tonorezos","sequence":"additional","affiliation":[{"name":"Department of Medicine, Weill Cornell Medical College, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8721-4858","authenticated-orcid":true,"given":"Laura A.","family":"Petrillo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Massachusetts General Hospital, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelley Fuld","family":"Nasso","sequence":"additional","affiliation":[{"name":"National Coalition for Cancer Survivorship, Silver Spring, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bethany","family":"Ross","sequence":"additional","affiliation":[{"name":"National Coalition for Cancer Survivorship, Silver Spring, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3766-468X","authenticated-orcid":true,"given":"Evan M.","family":"Graboyes","sequence":"additional","affiliation":[{"name":"Hollings Cancer Center, Medical University of South Carolina, Charleston, SC"},{"name":"Department of Otolaryngology-Head &amp; Neck Surgery, Medical University of South Carolina, Charleston, SC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djae135"},{"key":"e_1_3_5_3_2","volume-title":"From Cancer Patient to Cancer Survivor: Lost in Transition","author":"Institute of Medicine and National Research Council","unstructured":"Institute of Medicine and National Research Council: From Cancer Patient to Cancer Survivor: Lost in Transition. 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