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We then discuss historic legal frameworks designed to support PWD, and barriers to oncology care faced by PWD, organized around the following primary topics: (1) biases faced by PWD from health care professionals, (2) screening, (3) diagnosis, (4) treatment, (5) survivorship, and (6) historical exclusion from oncology research. We conclude by identifying key areas that must be addressed to provide high-quality oncologic care for PWD. A variety of suggestions for addressing these issues are presented, including additional education of oncology providers, rethinking performance status, engaging stakeholders in the disability community, improving enrollment in clinical trials for PWD, and collecting consistent disability-related data.<\/jats:p>","DOI":"10.1200\/op-26-00656","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:00:26Z","timestamp":1791921626000},"update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Promoting High-Quality, Accessible Cancer Care for People With Disabilities"],"prefix":"10.1200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9936-8750","authenticated-orcid":true,"given":"Sean","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7972-7071","authenticated-orcid":true,"given":"Maggie","family":"Salinger","sequence":"additional","affiliation":[{"name":"Department of Medicine, Warren Alpert Medical School of Brown University, Providence, RI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3047-2554","authenticated-orcid":true,"given":"Rebecca A.","family":"Spence","sequence":"additional","affiliation":[{"name":"American Society of Clinical Oncology, Alexandria, VA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1736-898X","authenticated-orcid":true,"given":"Ash B.","family":"Alpert","sequence":"additional","affiliation":[{"name":"Yale Cancer Center, Yale School of Medicine, Yale University, New Haven, CT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2221-9818","authenticated-orcid":true,"given":"Deborah B.","family":"Doroshow","sequence":"additional","affiliation":[{"name":"Tisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Hamroun-Yazid","sequence":"additional","affiliation":[{"name":"ChristianaCare Oncology Patient Advocates for Clinical Trials, Newark, DE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4827-8613","authenticated-orcid":true,"given":"Yara","family":"Abdou","sequence":"additional","affiliation":[{"name":"Division of Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5330-7247","authenticated-orcid":true,"given":"Samilia","family":"Obeng-Gyasi","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3734-5710","authenticated-orcid":true,"given":"Lori J.","family":"Pierce","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of Michigan, Ann Arbor, MI"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","published-online":{"date-parts":[[2026,10,13]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2022.00520"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1037\/rep0000317"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2021.01136"},{"key":"e_1_3_5_5_2","volume-title":"Disability Datasets: Disability and health data System (DHDS)","author":"CDC","year":"2025","unstructured":"CDC: Disability Datasets: Disability and health data System (DHDS), 2025. https:\/\/www.cdc.gov\/dhds\/datasets\/index.html"},{"key":"e_1_3_5_6_2","first-page":"qxaf137","article-title":"The disability mismatch: The case for a comprehensive disability status measure","volume":"3","author":"Landes SD","year":"2025","unstructured":"Landes SD, Swenor BK, Hall JP, et al: The disability mismatch: The case for a comprehensive disability status measure. 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