{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:54:31Z","timestamp":1747194871305,"version":"3.40.5"},"reference-count":14,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"9","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Oncology Practice"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec><jats:title>PURPOSE:<\/jats:title><jats:p> The objective of this study was to describe the implementation of an interdisciplinary supportive care program for treatment-related adverse effects (TRAEs) of patients with cancer in two ambulatory infusion centers affiliated with a major health system. <\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p> A management program of TRAEs was developed on the basis of the collaboration between oncologists, infusion center oncology nurses, and a board-certified oncology clinical pharmacist for patients with cancer in two outpatient infusion centers. Patients received multidisciplinary interventions or oncologist-driven interventions on the basis of their reported symptoms during their cancer treatments. They were followed prospectively at regular intervals for further symptom management interventions. To evaluate this program, a retrospective chart review was performed, and data were collected regarding the number and nature of these TRAEs. The outcomes of their interventions were assessed up to 3 months since initial encounters. Data for patient satisfaction were also collected before and after implementation of the program. <\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p> A total of 308 patients received 469 interventions initiated either by the multidisciplinary team or by oncologists over a 3-year period. Compared with oncologist-led interventions, multidisciplinary interventions were statistically significant in the number of interventions ( P = .004; 95% CI, 17.9 to 36.2) and in reducing occurrences of TRAEs ( P = .03; 95% CI, 33.8 to 72.4) such as dermatological toxicities, diarrhea, immune-related adverse effects, mucositis, and nausea or vomiting after 1-month follow-up. Multidisciplinary team captured approximately 40% of TRAEs of all grades that were escalated to oncologists for further management, which led to an overall improvement in management of TRAEs. <\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION:<\/jats:title><jats:p> Multidisciplinary care for patients in infusion centers led to improvement in treatment-related toxicities. <\/jats:p><\/jats:sec>","DOI":"10.1200\/op.21.00910","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T19:59:25Z","timestamp":1656705565000},"page":"e1553-e1561","update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":1,"title":["Optimizing Multidisciplinary Treatment-Related Adverse Effects Detection and Reduction in Patients Undergoing Active Cancer Treatments in Ambulatory Infusion Centers"],"prefix":"10.1200","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7189-6612","authenticated-orcid":false,"given":"Clement","family":"Chung","sequence":"first","affiliation":[{"name":"Houston Methodist West Hospital, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0006-3530","authenticated-orcid":false,"given":"Alison","family":"Rome","sequence":"additional","affiliation":[{"name":"Houston Methodist West Hospital, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3090-1929","authenticated-orcid":false,"given":"Monica","family":"Desai","sequence":"additional","affiliation":[{"name":"Houston Methodist West Hospital, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred","family":"Abanonu","sequence":"additional","affiliation":[{"name":"Houston Methodist West Hospital, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesar","family":"De la Casas","sequence":"additional","affiliation":[{"name":"Houston Methodist Baytown Hospital, Baytown, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"233","reference":[{"doi-asserted-by":"publisher","key":"b1","DOI":"10.1188\/11.CJON.175-179"},{"doi-asserted-by":"publisher","key":"b2","DOI":"10.1007\/s11096-020-00992-8"},{"doi-asserted-by":"publisher","key":"b3","DOI":"10.1016\/j.suronc.2011.06.004"},{"doi-asserted-by":"publisher","key":"b4","DOI":"10.1007\/s11096-016-0297-2"},{"doi-asserted-by":"publisher","key":"b5","DOI":"10.1111\/jcpt.12562"},{"doi-asserted-by":"publisher","key":"b6","DOI":"10.2146\/ajhp160475"},{"doi-asserted-by":"publisher","key":"b7","DOI":"10.1007\/s00520-021-06239-0"},{"doi-asserted-by":"publisher","key":"b8","DOI":"10.1177\/0897190014557626"},{"doi-asserted-by":"publisher","key":"b11","DOI":"10.1016\/j.annonc.2020.07.003"},{"doi-asserted-by":"publisher","key":"b12","DOI":"10.1093\/annonc\/mdy145"},{"doi-asserted-by":"publisher","key":"b13","DOI":"10.1177\/1078155218765629"},{"doi-asserted-by":"publisher","key":"b14","DOI":"10.1182\/blood-2020-142864"},{"doi-asserted-by":"publisher","key":"b15","DOI":"10.1001\/jama.2017.7156"},{"doi-asserted-by":"publisher","key":"b16","DOI":"10.1200\/JCO.2015.63.0830"}],"container-title":["JCO Oncology Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/OP.21.00910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T22:03:03Z","timestamp":1663020183000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/OP.21.00910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1200\/OP.21.00910"],"URL":"https:\/\/doi.org\/10.1200\/op.21.00910","relation":{},"ISSN":["2688-1527","2688-1535"],"issn-type":[{"type":"print","value":"2688-1527"},{"type":"electronic","value":"2688-1535"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"2021-12-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-25","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}