{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:32:24Z","timestamp":1785353544916,"version":"3.55.0"},"reference-count":26,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"12","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Oncol Pract"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n            <jats:title>PURPOSE<\/jats:title>\n            <jats:p>There is a lack of systematic solutions to manage supportive care issues in racial\/ethnic minorities (REM) receiving treatment for cancer. We developed and implemented an electronic patient-reported outcome (ePRO)\u2013driven symptom management tool led by oncology pharmacists in a majority-minority cancer center located in Southern California. This study was designed to evaluate the implementation outcomes of our multilevel intervention.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS<\/jats:title>\n            <jats:p>This was a prospective, pragmatic, implementation study conducted between July 2021 and June 2023. Newly diagnosed adult patients with cancer receiving intravenous anticancer therapies completed symptom screening using ePRO that consists of the Patient-Reported Outcomes Measurement Information System measures at each infusion visit during the study. ePRO results were presented to an oncologist pharmacist for personalized symptom management and treatment counseling. The RE-AIM framework was used to guide implementation outcomes. Differences in symptom trajectories and clinical outcomes between groups were tested using generalized estimating equations.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS<\/jats:title>\n            <jats:p>\n              We screened 388 patients of whom 250 were enrolled (acceptance rate: 64.4%), with 564 assessments being completed. The sample consisted of non-Hispanic White (NHW, 42.4%), Hispanic\/Latinx (H\/L, 30.8%), and non-Hispanic Asian (20.4%), with one (21.6%) of five participants preferring speaking Spanish. Compared with NHW, H\/L participants had greater odds of reporting mild to severe pain interference (odds ratio [OR], 1.91 [95% CI, 1.18 to 3.08];\n              <jats:italic>P<\/jats:italic>\n              = .008) and nausea and vomiting (OR, 2.08 [95% CI, 1.21 to 3.58];\n              <jats:italic>P<\/jats:italic>\n              = .008), and higher rates of urgent care utilization (OR, 1.92 [95% CI, 1.04 to 3.61];\n              <jats:italic>P<\/jats:italic>\n              = .04) within 30 days. Nausea and vomiting (n = 131, 23.2%), pain (n = 91, 16.1%), and fatigue (n = 72, 12.8%) were most likely to be intervened, with 90% of the participants expressing satisfaction across all visits.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSION<\/jats:title>\n            <jats:p>Our multilevel ePRO-driven intervention led by oncology pharmacists helps facilitate symptom assessments and management and potentially reduce health disparities among REM.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1200\/op.24.00050","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T20:03:12Z","timestamp":1721073792000},"page":"1744-1754","update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":11,"title":["Electronic Patient-Reported Outcome-Driven Symptom Management by Oncology Pharmacists in a Majority-Minority Population: An Implementation Study"],"prefix":"10.1200","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4391-4219","authenticated-orcid":true,"given":"Alexandre","family":"Chan","sequence":"first","affiliation":[{"name":"School of Pharmacy &amp; Pharmaceutical Sciences, University of California Irvine, Irvine, CA"},{"name":"Department of Pharmacy, Chao Family Comprehensive Cancer Center, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0754-7901","authenticated-orcid":true,"given":"Ding Quan","family":"Ng","sequence":"additional","affiliation":[{"name":"School of Pharmacy &amp; Pharmaceutical Sciences, University of California Irvine, Irvine, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7634-8818","authenticated-orcid":true,"given":"Daniela","family":"Arcos","sequence":"additional","affiliation":[{"name":"School of Pharmacy &amp; Pharmaceutical Sciences, University of California Irvine, Irvine, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2831-5106","authenticated-orcid":true,"given":"Matthew","family":"Heshmatipour","sequence":"additional","affiliation":[{"name":"School of Pharmacy &amp; Pharmaceutical Sciences, University of California Irvine, Irvine, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1678-1345","authenticated-orcid":true,"given":"Benjamin J.","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Pharmacy &amp; Pharmaceutical Sciences, University of California Irvine, Irvine, CA"},{"name":"Department of Pharmacy, Chao Family Comprehensive Cancer Center, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0129-8711","authenticated-orcid":true,"given":"Alison","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Chao Family Comprehensive Cancer Center, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Duong","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Chao Family Comprehensive Cancer Center, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Van","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Chao Family Comprehensive Cancer Center, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Chao Family Comprehensive Cancer Center, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vuong","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Chao Family Comprehensive Cancer Center, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Hoang","sequence":"additional","affiliation":[{"name":"School of Pharmacy &amp; Pharmaceutical Sciences, University of California Irvine, Irvine, CA"},{"name":"Department of Pharmacy, Chao Family Comprehensive Cancer Center, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2014.02.005"},{"key":"e_1_3_6_3_2","first-page":"484","article-title":"The quality of cancer patient experience: Perspectives of patients, family members, providers and experts","volume":"19","author":"Wagner EH","year":"2010","unstructured":"Wagner EH, Aiello Bowles EJ, Greene SM, et al: The quality of cancer patient experience: Perspectives of patients, family members, providers and experts. Qual Saf Health Care 19:484-489, 2010","journal-title":"Qual Saf Health Care"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-015-2998-9"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/10781552211017199"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/1078155216634180"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/1078155210389217"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-017-0680-2"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2008.05.005"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2014.11.002"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.847696"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0b013e3182408812"},{"key":"e_1_3_6_13_2","volume-title":"Catchment Area","year":"2023","unstructured":"Catchment Area. 2023. https:\/\/cancer.uci.edu\/about\/catchment-area"},{"key":"e_1_3_6_14_2","volume-title":"PROMIS\u00ae Score Cut Points","year":"2023","unstructured":"PROMIS\u00ae Score Cut Points. Northwestern University, 2023. https:\/\/www.healthmeasures.net\/score-and-interpret\/interpret-scores\/promis\/promis-score-cut-points"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-019-04931-w"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.02.016"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.89.9.1322"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2018.304883"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-021-06545-7"},{"key":"e_1_3_6_20_2","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_200383"},{"key":"e_1_3_6_21_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.53.5948"},{"key":"e_1_3_6_22_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.06.078"},{"key":"e_1_3_6_23_2","volume-title":"2022 National Healthcare Quality and Disparities Report","unstructured":"2022 National Healthcare Quality and Disparities Report. https:\/\/www.ahrq.gov\/sites\/default\/files\/wysiwyg\/research\/findings\/nhqrdr\/2022qdr-final-es.pdf"},{"key":"e_1_3_6_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4124"},{"key":"e_1_3_6_25_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21788"},{"key":"e_1_3_6_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.1078"},{"key":"e_1_3_6_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-019-02312-8"}],"container-title":["JCO Oncology Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/OP.24.00050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T23:00:50Z","timestamp":1733958050000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/OP.24.00050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1200\/OP.24.00050"],"URL":"https:\/\/doi.org\/10.1200\/op.24.00050","relation":{},"ISSN":["2688-1527","2688-1535"],"issn-type":[{"value":"2688-1527","type":"print"},{"value":"2688-1535","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-01-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-02","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}