{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:35:42Z","timestamp":1790660142690,"version":"4.1.0"},"reference-count":46,"publisher":"American Society of Clinical Oncology (ASCO)","issue":"3","content-domain":{"domain":["ascopubs.org"],"crossmark-restriction":true},"short-container-title":["JCO Precis Oncol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE<\/jats:title>\n                    <jats:p>\n                      Fanconi anemia (FA) is a genetic disorder typically characterized by progressive bone marrow failure (BMF) during childhood, leading to diagnosis at that stage. In adolescence or adulthood, patients are predisposed to myelodysplastic syndrome (MDS), acute myeloid leukemia, and solid tumors. However, some individuals present atypically, delaying FA recognition and resulting in life-threatening complications. This study describes the distinctive phenotype associated with biallelic\n                      <jats:italic toggle=\"yes\">FANCM<\/jats:italic>\n                      pathogenic variants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS<\/jats:title>\n                    <jats:p>\n                      Clinical and biologic data were analyzed from eight patients carrying biallelic germline\n                      <jats:italic toggle=\"yes\">FANCM<\/jats:italic>\n                      pathogenic variants within a French cohort of 411 patients with FA (2.0%). Clinical outcomes were compared with those of patients with FA carrying non-\n                      <jats:italic toggle=\"yes\">FANCM<\/jats:italic>\n                      variants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      None of the eight\n                      <jats:italic toggle=\"yes\">FANCM<\/jats:italic>\n                      patients developed BMF, contrasting with a 93.5% cumulative incidence among other FA genotypes (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .0001). This absence of marrow failure resulted in delayed FA diagnosis (median age 23.5\n                      <jats:italic toggle=\"yes\">v<\/jats:italic>\n                      6.8 years,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .01). Instead, six patients initially presented with malignancy and exhibited marked toxicity to conventional cancer therapies, prompting FA testing. Malignancies included four oral cancers and, unexpectedly, two ALL: a ZNF384-rearranged B-cell precursor ALL and a BCL11B::HOXA13 early T-cell precursor ALL. No ALL cases occurred among the 403 non-\n                      <jats:italic toggle=\"yes\">FANCM<\/jats:italic>\n                      patients with FA (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .0001). The treatment courses of the two\n                      <jats:italic toggle=\"yes\">FANCM<\/jats:italic>\n                      -related ALL cases are reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>\n                      Biallelic\n                      <jats:italic toggle=\"yes\">FANCM<\/jats:italic>\n                      variants define a distinct FA subtype lacking early BMF, leading to missed diagnoses and severe toxicity upon malignancy. Recognizing this presentation is crucial for timely FA detection and for implementing adapted therapeutic and follow-up strategies.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1200\/po-25-01089","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T19:59:09Z","timestamp":1774468749000},"update-policy":"https:\/\/doi.org\/10.1200\/crossmark","source":"Crossref","is-referenced-by-count":3,"title":["Predisposition to ALL and Solid Tumors Rather Than Bone Marrow Failure in\n                    <i>FANCM<\/i>\n                    -Associated Fanconi Anemia"],"prefix":"10.1200","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4954-5744","authenticated-orcid":true,"given":"Francesco","family":"Pegoraro","sequence":"first","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"},{"name":"The Leukemia Institute Paris Saint-Louis, Paris, France"},{"name":"Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9461-0728","authenticated-orcid":true,"given":"Lise","family":"Larcher","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"},{"name":"The Leukemia Institute Paris Saint-Louis, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9987-7237","authenticated-orcid":true,"given":"Rathana","family":"Kim","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9lanie","family":"Pag\u00e8s","sequence":"additional","affiliation":[{"name":"Service de G\u00e9n\u00e9tique, Institut Curie, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4620-8782","authenticated-orcid":true,"given":"Marie","family":"Passet","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Caye-Eude","sequence":"additional","affiliation":[{"name":"D\u00e9partement de G\u00e9n\u00e9tique, Service de G\u00e9n\u00e9tique Mol\u00e9culaire, H\u00f4pital Robert Debr\u00e9, Assistance Publique des H\u00f4pitaux de Paris (APHP), Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mony","family":"Fahd","sequence":"additional","affiliation":[{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"},{"name":"Service de P\u00e9diatrie H\u00e9matologique et Immunologique, Robert-Debr\u00e9 Hospital, GHU AP-HP Nord, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0663-3429","authenticated-orcid":true,"given":"Benoit","family":"Brethon","sequence":"additional","affiliation":[{"name":"Service de P\u00e9diatrie H\u00e9matologique et Immunologique, Robert-Debr\u00e9 Hospital, GHU AP-HP Nord, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucie","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Vasquez","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9lanie","family":"Da Costa","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9744-4470","authenticated-orcid":true,"given":"Nathalie","family":"Auger","sequence":"additional","affiliation":[{"name":"Laboratoire de Cytog\u00e9n\u00e9tique et G\u00e9n\u00e9tique des Tumeurs, Institut Gustave Roussy, Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Lachaud","sequence":"additional","affiliation":[{"name":"Aix-Marseille Univ, INSERM, CNRS, Institut Paoli-Calmettes, CRCM, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2492-9802","authenticated-orcid":true,"given":"Marie","family":"de Tersant","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Luporsi","sequence":"additional","affiliation":[{"name":"CHR Metz-Thionville UF 4128 H\u00f4pital Femme, M\u00e8re, Enfant, Metz, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4376-4097","authenticated-orcid":true,"given":"Marie","family":"S\u00e9bert","sequence":"additional","affiliation":[{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"The Leukemia Institute Paris Saint-Louis, Paris, France"},{"name":"Service H\u00e9matologie Senior, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Hugues","family":"Dalle","sequence":"additional","affiliation":[{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"The Leukemia Institute Paris Saint-Louis, Paris, France"},{"name":"Service de P\u00e9diatrie H\u00e9matologique et Immunologique, Robert-Debr\u00e9 Hospital, GHU AP-HP Nord, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6222-4753","authenticated-orcid":true,"given":"R\u00e9gis","family":"Peffault de Latour","sequence":"additional","affiliation":[{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"The Leukemia Institute Paris Saint-Louis, Paris, France"},{"name":"Service H\u00e9matologie Greffe, H\u00f4pital Saint-Louis, APHP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7098-092X","authenticated-orcid":true,"given":"Emmanuelle","family":"Clappier","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"The Leukemia Institute Paris Saint-Louis, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5438-8309","authenticated-orcid":true,"given":"Dominique","family":"Stoppa-Lyonnet","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Service de G\u00e9n\u00e9tique, Institut Curie, Paris, France"},{"name":"Inserm U1339, Institut Curie, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Leblanc","sequence":"additional","affiliation":[{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"},{"name":"Service de P\u00e9diatrie H\u00e9matologique et Immunologique, Robert-Debr\u00e9 Hospital, GHU AP-HP Nord, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Paillard","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Oncologie P\u00e9diatrique, CHRU Hautepierre, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flore","family":"Sicre de Fontbrune","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"},{"name":"Inserm U1339, Institut Curie, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8734-5356","authenticated-orcid":true,"given":"Jean","family":"Soulier","sequence":"additional","affiliation":[{"name":"Service H\u00e9matologie Biologique, H\u00f4pital Saint-Louis, Assistance Publique H\u00f4pitaux de Paris (APHP), Paris, France"},{"name":"Inserm UMR1342 and CNRS EMR8000, Institut de Recherche Saint-Louis (IRSL), Paris, France"},{"name":"Universit\u00e9 Paris-Cit\u00e9, Paris, France"},{"name":"Centre de R\u00e9f\u00e9rence des Aplasies M\u00e9dullaires Acquises et Constitutionnelles (CeRAMIC), H\u00f4pitaux Saint-Louis Robert Debr\u00e9, APHP, Paris, France"},{"name":"The Leukemia Institute Paris Saint-Louis, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"233","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2010.03.002"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2016.48"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2011.1.492"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2023.01.006"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-06-1970"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-09-3138"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddad017"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/517616"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019003249"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000484749"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000069805"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-05-1852"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-07-2638"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26234"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2015.07.002"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1626"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004494"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2017.124"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.30490"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2017.123"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2018.07.005"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41436-018-0015-7"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2019.1711075"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2021.104399"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.13592"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-02-207811"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-022-01613-1"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.04.010"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/hem3.70025"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-020-0994-2"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.28.3390"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.20348"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-21-0145"},{"key":"e_1_3_5_35_2","first-page":"773","article-title":"14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T-lymphoid and myeloid immature acute leukemia","volume":"138","author":"Di Giacomo D","year":"2021","unstructured":"Di Giacomo D, La Starza R, Gorello P, et al: 14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T-lymphoid and myeloid immature acute leukemia. Blood 138:773-784, 2021","journal-title":"Blood"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.03.003"},{"key":"e_1_3_5_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.01.039"},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.01.036"},{"key":"e_1_3_5_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dnarep.2024.103701"},{"key":"e_1_3_5_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2008.10.014"},{"key":"e_1_3_5_41_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/238731"},{"key":"e_1_3_5_42_2","volume-title":"Fanconi Anemia Clinical Care Guidelines","author":"Fanconi Anemia Research Fund","year":"2020","unstructured":"Fanconi Anemia Research Fund. Fanconi Anemia Clinical Care Guidelines. 5th ed. Eugene, OR: Fanconi Anemia Research Fund, 2020","edition":"5"},{"key":"e_1_3_5_43_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-24-0685"},{"key":"e_1_3_5_44_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2022017735"},{"key":"e_1_3_5_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34277"},{"key":"e_1_3_5_46_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1913948"},{"key":"e_1_3_5_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gim.2023.101042"}],"container-title":["JCO Precision Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascopubs.org\/doi\/pdfdirect\/10.1200\/PO-25-01089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T19:59:14Z","timestamp":1774468754000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascopubs.org\/doi\/10.1200\/PO-25-01089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1200\/PO-25-01089"],"URL":"https:\/\/doi.org\/10.1200\/po-25-01089","relation":{},"ISSN":["2473-4284"],"issn-type":[{"value":"2473-4284","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-08","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2501089"}}