{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T17:34:08Z","timestamp":1788370448675,"version":"build-2803163510"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2001,3,1]],"date-time":"2001-03-01T00:00:00Z","timestamp":983404800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AAPS PharmSci"],"published-print":{"date-parts":[[2001,3]]},"DOI":"10.1208\/ps030103","type":"journal-article","created":{"date-parts":[[2003,10,6]],"date-time":"2003-10-06T17:29:17Z","timestamp":1065461357000},"page":"18-25","source":"Crossref","is-referenced-by-count":28,"title":["Physical chemical stability of warfarin sodium"],"prefix":"10.1208","volume":"3","author":[{"given":"Danchen","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Maurin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2001,3,1]]},"reference":[{"key":"31018_CR1","unstructured":"Schroeder CH, Link KP, inventors, Wisconsin Alumni Research Foundation. Warfarin sodium, US patent 3077 481. February 12, 1963."},{"key":"31018_CR2","volume-title":"The National Formulary, USP 24\/NF19","author":"US Pharmacopoeia","year":"2000","unstructured":"US Pharmacopoeia. The National Formulary, USP 24\/NF19, United States Pharmacopocia Convention: Rockville. Md. 2000."},{"key":"31018_CR3","unstructured":"Physicians Desk Reference\u00ae; 2000:969\u2013974. Medical Economics Company, Inc. Montvale, NJ, 54th edition."},{"key":"31018_CR4","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1002\/jps.2600540916","volume":"54","author":"CF Hiskey","year":"1965","unstructured":"Hiskey CF, Melnitchenko V. Clathrates of sodium warfarin. J Pharm Sci. 1965;54:1298\u20131302.","journal-title":"J Pharm Sci."},{"key":"31018_CR5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0378-5173(97)04895-3","volume":"151","author":"D Gao","year":"1997","unstructured":"Gao D, Rytting JH. Use of solution calorimetry to determine the extent of crystallinity of drugs and excipients. Int J Pharm. 1997;151:183\u2013192.","journal-title":"Int J Pharm."},{"key":"31018_CR6","first-page":"47","volume":"4","author":"H Nyqvist","year":"1983","unstructured":"Nyqvist H. Saturated salt solutions for maintaining specified relative humidities. J Pharm Tech Prod Mfr. 1983;4:47\u201348.","journal-title":"J Pharm Tech Prod Mfr."},{"key":"31018_CR7","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0731-7085(99)00142-9","volume":"21","author":"SR Rabel","year":"1999","unstructured":"Rabel SR, Jona JA, Maurin MB. Applications of modulated differential scanning calorimetry in preformulation studies. J Pharm Biomed Anal. 1999;21:339\u2013345.","journal-title":"J Pharm Biomed Anal."},{"key":"31018_CR8","doi-asserted-by":"crossref","first-page":"653","DOI":"10.3109\/03639048709105213","volume":"13","author":"K Umprayn","year":"1987","unstructured":"Umprayn K, Mendes RW. Hygroscopicity and moisture absorption kinetics of pharmaceutical solids a review. Drug Dev Ind Pharm. 1987;13:653\u2013693.","journal-title":"Drug Dev Ind Pharm."},{"key":"31018_CR9","volume-title":"Water solubility and sensitivity-hydration effects, chemistry and technology of water soluble polymers","year":"1981","unstructured":"Franks F, Finch CA, eds. Water solubility and sensitivity-hydration effects, chemistry and technology of water soluble polymers. New York, NY: Plenum Press, 1981."},{"key":"31018_CR10","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1023\/A:1018901325842","volume":"10","author":"BC Hancock","year":"1993","unstructured":"Hancock BC, Zografi G. The use of solution theories for predicting water vapor absorption by amorphous pharmaceutical solids a test of the Flory-Huggins and Vrental models. Pharm Res. 1993;10:1262\u20131267.","journal-title":"Pharm Res."},{"key":"31018_CR11","volume-title":"Polymer Chemistry, An Introduction","author":"RB Seymour","year":"1992","unstructured":"Seymour RB, Carraher CE Jr. Polymer Chemistry, An Introduction. 3rd ed. New York: Marcel Dekker, Inc.: 1992.","edition":"3rd ed."},{"key":"31018_CR12","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1023\/A:1018941810744","volume":"11","author":"BC Hancock","year":"1994","unstructured":"Hancock BC, Zografi G. The relationship between the glass transition temperature and the water content of amorphous pharmaceutical solids. Pharm Res. 1994;11:471\u2013477.","journal-title":"Pharm Res."},{"key":"31018_CR13","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1021\/cr50029a002","volume":"59","author":"L Mandelcom","year":"1959","unstructured":"Mandelcom L. Clathrates Chem Rev. 1959;59:827\u2013839.","journal-title":"Clathrates Chem Rev."}],"container-title":["AAPS PharmSci"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1208\/ps030103.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1208\/ps030103\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1208\/ps030103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T23:41:56Z","timestamp":1559605316000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1208\/ps030103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,3]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,3]]}},"alternative-id":["31018"],"URL":"https:\/\/doi.org\/10.1208\/ps030103","relation":{},"ISSN":["1522-1059"],"issn-type":[{"value":"1522-1059","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,3]]}}}