{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:08:45Z","timestamp":1778659725334,"version":"3.51.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["AAPS PharmSciTech"],"DOI":"10.1208\/s12249-022-02484-6","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T17:04:34Z","timestamp":1671210274000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Dry Suspension Containing Coated Pellets with pH-Dependent Drug Release Behavior for the Taste-masking of Azithromycin"],"prefix":"10.1208","volume":"24","author":[{"given":"Yangyan","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuanbin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,12,16]]},"reference":[{"issue":"2","key":"2484_CR1","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1208\/s12249-022-02227-7","volume":"23","author":"W Zhang","year":"2022","unstructured":"Zhang W, Li G, Xiao C, Chang X, Sun Y, Fan W, et al. Mesoporous silica carrier-based composites for taste-masking of bitter drug: fabrication and palatability evaluation. AAPS PharmSciTech. 2022;23(2):75. https:\/\/doi.org\/10.1208\/s12249-022-02227-7.","journal-title":"AAPS PharmSciTech"},{"issue":"2","key":"2484_CR2","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/j.ijpharm.2017.08.088","volume":"536","author":"R Ternik","year":"2018","unstructured":"Ternik R, Liu F, Bartlett JA, Khong YM, Thiam Tan DC, Dixit T, et al. Assessment of swallowability and palatability of oral dosage forms in children: report from an M-CERSI pediatric formulation workshop. Int J Pharm. 2018;536(2):570\u201381. https:\/\/doi.org\/10.1016\/j.ijpharm.2017.08.088.","journal-title":"Int J Pharm"},{"key":"2484_CR3","doi-asserted-by":"publisher","first-page":"3855","DOI":"10.2147\/DDDT.S183534","volume":"12","author":"F Amin","year":"2018","unstructured":"Amin F, Khan S, Shah SMH, Rahim H, Hussain Z, Sohail M, et al. A new strategy for taste masking of azithromycin antibiotic: development, characterization, and evaluation of azithromycin titanium nanohybrid for masking of bitter taste using physisorption and panel testing studies. Drug Des Devel Ther. 2018;12:3855\u201366. https:\/\/doi.org\/10.2147\/DDDT.S183534.","journal-title":"Drug Des Devel Ther"},{"key":"2484_CR4","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.2147\/ijn.S183479","volume":"14","author":"C Li","year":"2019","unstructured":"Li C, Zhou K, Chen D, Xu W, Tao Y, Pan Y, et al. Solid lipid nanoparticles with enteric coating for improving stability, palatability, and oral bioavailability of enrofloxacin. Int J Nanomedicine. 2019;14:1619\u201331. https:\/\/doi.org\/10.2147\/ijn.S183479.","journal-title":"Int J Nanomedicine"},{"issue":"5","key":"2484_CR5","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1080\/03639045.2016.1220567","volume":"43","author":"BB Alsulays","year":"2017","unstructured":"Alsulays BB, Kulkarni V, Alshehri SM, Almutairy BK, Ashour EA, Morott JT, et al. Preparation and evaluation of enteric coated tablets of hot-melt extruded lansoprazole. Drug Dev Ind Pharm. 2017;43(5):789\u201396. https:\/\/doi.org\/10.1080\/03639045.2016.1220567.","journal-title":"Drug Dev Ind Pharm"},{"key":"2484_CR6","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.addr.2014.02.012","volume":"73","author":"J Walsh","year":"2014","unstructured":"Walsh J, Cram A, Woertz K, Breitkreutz J, Winzenburg G, Turner R, et al. Playing hide and seek with poorly tasting paediatric medicines: do not forget the excipients. Adv Drug Deliv Rev. 2014;73:14\u201333. https:\/\/doi.org\/10.1016\/j.addr.2014.02.012.","journal-title":"Adv Drug Deliv Rev"},{"issue":"4","key":"2484_CR7","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1208\/s12249-019-1343-x","volume":"20","author":"K Liu","year":"2019","unstructured":"Liu K, Meng Z, Li Y, Liu J, Xu Y, Wang Y, et al. Preparation and evaluation of mosapride citrate dual-release dry suspension. AAPS PharmSciTech. 2019;20(4):155. https:\/\/doi.org\/10.1208\/s12249-019-1343-x.","journal-title":"AAPS PharmSciTech"},{"key":"2484_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/b978-0-12-800173-8.00001-5","volume":"39","author":"AH Bakheit","year":"2014","unstructured":"Bakheit AH, Al-Hadiya BM, Abd-Elgalil AA. Azithromycin. Profiles Drug Subst Excip Relat Methodol. 2014;39:1\u201340. https:\/\/doi.org\/10.1016\/b978-0-12-800173-8.00001-5.","journal-title":"Profiles Drug Subst Excip Relat Methodol"},{"issue":"4","key":"2484_CR9","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1080\/02652040500100600","volume":"22","author":"MC Adeyeye","year":"2005","unstructured":"Adeyeye MC, Mwangi E, Katondo B, Jain A, Ichikawa H, Fukumori Y. Dissolution stability studies of suspensions of prolonged-release diclofenac microcapsules prepared by the Wurster process: I. Eudragit-based formulation and possible drug-excipient interaction. J Microencapsul. 2005;22(4):333\u201342. https:\/\/doi.org\/10.1080\/02652040500100600.","journal-title":"J Microencapsul."},{"issue":"10","key":"2484_CR10","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1080\/10837450.2017.1412460","volume":"23","author":"F Klar","year":"2018","unstructured":"Klar F, Urbanetz NA. High efficiency dry coating of non-subcoated pellets for sustained drug release formulations using amino methacrylate copolymers. Pharm Dev Technol. 2018;23(10):1088\u201396. https:\/\/doi.org\/10.1080\/10837450.2017.1412460.","journal-title":"Pharm Dev Technol"},{"key":"2484_CR11","doi-asserted-by":"publisher","unstructured":"Serrano DR, Fernandez-Garcia R, Mele M, Healy AM, Lalatsa A. Designing fast-dissolving orodispersible films of amphotericin B for oropharyngeal candidiasis. Pharm. 2019;11(8). https:\/\/doi.org\/10.3390\/pharmaceutics11080369.","DOI":"10.3390\/pharmaceutics11080369"},{"issue":"5","key":"2484_CR12","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1007\/s11095-021-03041-9","volume":"38","author":"Z Wang","year":"2021","unstructured":"Wang Z, Li J, Hong X, Han X, Liu B, Li X, et al. Taste masking study based on an electronic tongue: the formulation design of 3D printed levetiracetam instant-dissolving tablets. Pharm Res. 2021;38(5):831\u201342. https:\/\/doi.org\/10.1007\/s11095-021-03041-9.","journal-title":"Pharm Res"},{"key":"2484_CR13","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.ijpharm.2019.05.055","volume":"566","author":"J Mandi\u0107","year":"2019","unstructured":"Mandi\u0107 J, Lu\u0161trik M, Vre\u010der F, Ga\u0161perlin M, Zvonar PA. Solidification of carvedilol loaded SMEDDS by swirling fluidized bed pellet coating. Int J Pharm. 2019;566:89\u2013100. https:\/\/doi.org\/10.1016\/j.ijpharm.2019.05.055.","journal-title":"Int J Pharm"},{"issue":"3","key":"2484_CR14","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/S0939-6411(02)00015-2","volume":"53","author":"R Chopra","year":"2002","unstructured":"Chopra R, Podczeck F, Newton JM, Alderborn G. The influence of pellet shape and film coating on the filling of pellets into hard shell capsules. Eur J Pharm Biopharm. 2002;53(3):327\u201333. https:\/\/doi.org\/10.1016\/S0939-6411(02)00015-2.","journal-title":"Eur J Pharm Biopharm"},{"issue":"3","key":"2484_CR15","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1080\/03639045.2021.1879830","volume":"47","author":"MRP Rao","year":"2021","unstructured":"Rao MRP, Godbole RV, Borate SG, Mahajan S, Gangwal T. Nanosuspension coated multiparticulates for controlled delivery of albendazole. Drug Dev Ind Pharm. 2021;47(3):367\u201376. https:\/\/doi.org\/10.1080\/03639045.2021.1879830.","journal-title":"Drug Dev Ind Pharm"},{"issue":"3","key":"2484_CR16","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.jsps.2018.12.003","volume":"27","author":"HF Alotaibi","year":"2019","unstructured":"Alotaibi HF, Elsamaligy S, Mahrous GM, Bayomi MA, Mahmoud HA. Design of taste masked enteric orodispersible tablets of diclofenac sodium by applying fluid bed coating technology. Saudi Pharm J. 2019;27(3):354\u201362. https:\/\/doi.org\/10.1016\/j.jsps.2018.12.003.","journal-title":"Saudi Pharm J"},{"issue":"7","key":"2484_CR17","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1208\/s12249-019-1487-8","volume":"20","author":"L Zhang","year":"2019","unstructured":"Zhang L, Xu C, Mao J, Wang W, Han H, Pu Y, et al. Formulation and characterization of novel dry suspension and dry emulsion of 20(S)-Protopanaxadiol. AAPS PharmSciTech. 2019;20(7):275. https:\/\/doi.org\/10.1208\/s12249-019-1487-8.","journal-title":"AAPS PharmSciTech"},{"issue":"12","key":"2484_CR18","doi-asserted-by":"publisher","first-page":"1798","DOI":"10.1086\/320745","volume":"32","author":"EL Kaplan","year":"2001","unstructured":"Kaplan EL, Gooch IW, Notario GF, Craft JC. Macrolide therapy of group A streptococcal pharyngitis: 10 days of macrolide therapy (clarithromycin) is more effective in streptococcal eradication than 5 days (azithromycin). Clin Infect Dis. 2001;32(12):1798\u2013802. https:\/\/doi.org\/10.1086\/320745.","journal-title":"Clin Infect Dis"},{"issue":"3","key":"2484_CR19","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/j.ejpb.2006.11.018","volume":"66","author":"PC Kayumba","year":"2007","unstructured":"Kayumba PC, Huyghebaert N, Cordella C, Ntawukuliryayo JD, Vervaet C, Remon JP. Quinine sulphate pellets for flexible pediatric drug dosing: formulation development and evaluation of taste-masking efficiency using the electronic tongue. Eur J Pharm Biopharm. 2007;66(3):460\u20135. https:\/\/doi.org\/10.1016\/j.ejpb.2006.11.018.","journal-title":"Eur J Pharm Biopharm"},{"key":"2484_CR20","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.aca.2019.05.024","volume":"1077","author":"T Wasilewski","year":"2019","unstructured":"Wasilewski T, Migo\u0144 D, G\u0119bicki J, Kamysz W. Critical review of electronic nose and tongue instruments prospects in pharmaceutical analysis. Anal Chim Acta. 2019;1077:14\u201329. https:\/\/doi.org\/10.1016\/j.aca.2019.05.024.","journal-title":"Anal Chim Acta"},{"issue":"1\u20132","key":"2484_CR21","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.ijpharm.2010.11.028","volume":"417","author":"K Woertz","year":"2011","unstructured":"Woertz K, Tissen C, Kleinebudde P, Breitkreutz J. Taste sensing systems (electronic tongues) for pharmaceutical applications. Int J Pharm. 2011;417(1\u20132):256\u201371. https:\/\/doi.org\/10.1016\/j.ijpharm.2010.11.028.","journal-title":"Int J Pharm"}],"container-title":["AAPS PharmSciTech"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1208\/s12249-022-02484-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1208\/s12249-022-02484-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1208\/s12249-022-02484-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T14:11:11Z","timestamp":1714745471000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1208\/s12249-022-02484-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,16]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["2484"],"URL":"https:\/\/doi.org\/10.1208\/s12249-022-02484-6","relation":{},"ISSN":["1530-9932"],"issn-type":[{"value":"1530-9932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,16]]},"assertion":[{"value":"5 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}],"article-number":"21"}}