{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:44:43Z","timestamp":1792532683621,"version":"4.5.0"},"reference-count":67,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:00:00Z","timestamp":1722384000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:00:00Z","timestamp":1722384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["AAPS PharmSciTech"],"DOI":"10.1208\/s12249-024-02895-7","type":"journal-article","created":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:08:11Z","timestamp":1722470891000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Bioadhesive Polymeric Films Containing Rhamnolipids, An Innovative Antimicrobial Topical Formulation"],"prefix":"10.1208","volume":"25","author":[{"given":"J\u00e9ssica B.","family":"Carra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamila B. B.","family":"Wessel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovana N.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana C.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietra M. T.","family":"Pattini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca L.","family":"Masquetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismael R.","family":"Amador","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos L.","family":"Bruschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00fabia","family":"Casagrande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra R.","family":"Georgetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Waldiceu A.","family":"Verri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerson","family":"Nakazato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josiane A.","family":"Vignoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doumit","family":"Camilios-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0400-7413","authenticated-orcid":false,"given":"Marcela M.","family":"Baracat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,31]]},"reference":[{"key":"2895_CR1","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s13555-018-0275-9","volume":"9","author":"DE Castillo","year":"2019","unstructured":"Castillo DE, Nanda S, Keri JE. Propionibacterium (Cutibacterium) acnes bacteriophage therapy in acne: current evidence and future perspectives. Dermatol Ther (Heidelb). 2019;9:19\u201331.","journal-title":"Dermatol Ther (Heidelb)"},{"key":"2895_CR2","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1111\/ced.14239","volume":"45","author":"C Dessinioti","year":"2020","unstructured":"Dessinioti C, Dreno B. Acne treatments: future trajectories. Clin Exp Dermatol. 2020;45:955\u201361.","journal-title":"Clin Exp Dermatol"},{"key":"2895_CR3","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1007\/s13555-019-00320-7","volume":"9","author":"N Zhang","year":"2019","unstructured":"Zhang N, Yuan R, Xin KZ, Lu Z, Ma Y. Antimicrobial susceptibility, biotypes and phylotypes of clinical Cutibacterium (Formerly Propionibacterium) acnes strains isolated from acne patients: an observational study. Dermatol Ther (Heidelb). 2019;9:735\u201346.","journal-title":"Dermatol Ther (Heidelb)"},{"key":"2895_CR4","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/s40257-018-00417-3","volume":"20","author":"H Xu","year":"2019","unstructured":"Xu H, Li H. Acne, the skin microbiome, and antibiotic treatment. Am J Clin Dermatol. 2019;20:335\u201344. https:\/\/doi.org\/10.1007\/s40257-018-00417-3.","journal-title":"Am J Clin Dermatol"},{"key":"2895_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ijms23105797","volume":"23","author":"A Chudzik","year":"2022","unstructured":"Chudzik A, Migda\u0142 P, Pa\u015bciak M. Different Cutibacterium acnes phylotypes release distinct extracellular vesicles. Int J Mol Sci. 2022;23:1\u201313.","journal-title":"Int J Mol Sci"},{"key":"2895_CR6","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/jdv.15043","volume":"32","author":"B Dr\u00e9no","year":"2018","unstructured":"Dr\u00e9no B, P\u00e9castaings S, Corvec S, Veraldi S, Khammari A, Roques C. Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates. J Eur Acad Dermatol Venereol. 2018;32:5\u201314.","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2895_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/microorganisms7050128","volume":"7","author":"J McLaughlin","year":"2019","unstructured":"McLaughlin J, Watterson S, Layton AM, Bjourson AJ, Barnard E, McDowell A. Propionibacterium acnes and acne vulgaris: New insights from the integration of population genetic, multi-omic, biochemical and host-microbe studies. Microorganisms. 2019;7:1\u201329.","journal-title":"Microorganisms"},{"key":"2895_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2013\/918320","volume":"2013","author":"G Kasimatis","year":"2013","unstructured":"Kasimatis G, Fitz-Gibbon S, Tomida S, Wong M, Li H. Analysis of complete genomes of propionibacterium acnes reveals a novel plasmid and increased Pseudogenes in an acne associated strain. Biomed Res Int. 2013;2013:1\u201311.","journal-title":"Biomed Res Int"},{"key":"2895_CR9","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1007\/BF00412883","volume":"275","author":"M Gehse","year":"1983","unstructured":"Gehse M, H\u00f6ffer U, Gloor M, Pulverer G. Propionibacteria in patients with acne vulgaris and in healthy persons. Arch Dermatol Res. 1983;275:100\u20134.","journal-title":"Arch Dermatol Res"},{"key":"2895_CR10","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1007\/s40257-020-00556-6","volume":"21","author":"MA Kayiran","year":"2020","unstructured":"Kayiran MA, Karadag AS, Al-Khuzaei S, Chen WC, Parish LC. Antibiotic resistance in acne: mechanisms, complications and management. Am J Clin Dermatol. 2020;21:813\u20139. https:\/\/doi.org\/10.1007\/s40257-020-00556-6.","journal-title":"Am J Clin Dermatol"},{"key":"2895_CR11","doi-asserted-by":"publisher","unstructured":"Aziz ZAA, Setapar SHM, Khatoon A, Ahmad A. The potential use of biosurfactants in cosmetics and dermatological products. Biosurfactants a Sustain Futur Prod Appl Environ Biomed. 2021;397\u2013421. https:\/\/doi.org\/10.1002\/9781119671022.ch18.","DOI":"10.1002\/9781119671022.ch18"},{"key":"2895_CR12","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1007\/s00253-010-2498-2","volume":"86","author":"AM Abdel-Mawgoud","year":"2010","unstructured":"Abdel-Mawgoud AM, L\u00e9pine F, D\u00e9ziel E. Rhamnolipids: Diversity of structures, microbial origins and roles. Appl Microbiol Biotechnol. 2010;86:1323\u201336.","journal-title":"Appl Microbiol Biotechnol"},{"key":"2895_CR13","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1111\/j.1468-2494.2009.00493.x","volume":"31","author":"N Lourith","year":"2009","unstructured":"Lourith N, Kanlayavattanakul M. Natural surfactants used in cosmetics: Glycolipids. Int J Cosmet Sci. 2009;31:255\u201361.","journal-title":"Int J Cosmet Sci"},{"key":"2895_CR14","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.carres.2015.07.016","volume":"416","author":"M In\u00e8s","year":"2015","unstructured":"In\u00e8s M, Dhouha G. Glycolipid biosurfactants: Potential related biomedical and biotechnological applications. Carbohydr Res. 2015;416:59\u201369. https:\/\/doi.org\/10.1016\/j.carres.2015.07.016.","journal-title":"Carbohydr Res"},{"key":"2895_CR15","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.biortech.2017.02.047","volume":"232","author":"SJ Varjani","year":"2017","unstructured":"Varjani SJ, Upasani VN. Critical review on biosurfactant analysis, purification and characterization using rhamnolipid as a model biosurfactant. Bioresour Technol. 2017;232:389\u201397. https:\/\/doi.org\/10.1016\/j.biortech.2017.02.047.","journal-title":"Bioresour Technol"},{"key":"2895_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/pharmaceutics12111099","volume":"12","author":"SA Adu","year":"2020","unstructured":"Adu SA, Naughton PJ, Marchant R, Banat IM. Microbial biosurfactants in cosmetic and personal skincare pharmaceutical formulations. Pharmaceutics. 2020;12:1\u201321.","journal-title":"Pharmaceutics"},{"key":"2895_CR17","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.micres.2017.04.005","volume":"200","author":"B Shao","year":"2017","unstructured":"Shao B, Liu Z, Zhong H, Zeng G, Liu G, Yu M, et al. Effects of rhamnolipids on microorganism characteristics and applications in composting: A review. Microbiol Res. 2017;200:33\u201344.","journal-title":"Microbiol Res"},{"key":"2895_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12934-017-0753-2","volume":"16","author":"H Chong","year":"2017","unstructured":"Chong H, Li Q. Microbial production of rhamnolipids: Opportunities, challenges and strategies. Microb Cell Fact. 2017;16:1\u201312.","journal-title":"Microb Cell Fact"},{"key":"2895_CR19","doi-asserted-by":"publisher","first-page":"279","DOI":"10.2298\/JSC140627096R","volume":"80","author":"MG Rikalovi\u0107","year":"2015","unstructured":"Rikalovi\u0107 MG, Vrvi\u0107 MM, Karad\u017ei\u0107 Im. Rhamnolipid biosurfactant from Pseudomonas aeruginosa \u2013 from discovery to application in contemporary technology. J Serbian Chem Soc. 2015;80:279\u2013304.","journal-title":"J Serbian Chem Soc."},{"key":"2895_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12934-020-01497-9","volume":"20","author":"P Thakur","year":"2021","unstructured":"Thakur P, Saini NK, Thakur VK, Gupta VK, Saini RV, Saini AK. Rhamnolipid the Glycolipid Biosurfactant: Emerging trends and promising strategies in the field of biotechnology and biomedicine. Microb Cell Fact. 2021;20:1\u201315. https:\/\/doi.org\/10.1186\/s12934-020-01497-9.","journal-title":"Microb Cell Fact"},{"key":"2895_CR21","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1016\/j.foodres.2018.09.005","volume":"116","author":"JF de Ferreira","year":"2019","unstructured":"de Ferreira JF, Vieira EA, Nitschke M. The antibacterial activity of rhamnolipid biosurfactant is pH dependent. Food Res Int. 2019;116:737\u201344. https:\/\/doi.org\/10.1016\/j.foodres.2018.09.005.","journal-title":"Food Res Int."},{"key":"2895_CR22","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/j.colsurfb.2012.10.064","volume":"103","author":"P Bharali","year":"2013","unstructured":"Bharali P, Saikia JP, Ray A, Konwar BK. Rhamnolipid (RL) from Pseudomonas aeruginosa OBP1: A novel chemotaxis and antibacterial agent. Colloids Surf B Biointerfaces. 2013;103:502\u20139.","journal-title":"Colloids Surf B Biointerfaces"},{"key":"2895_CR23","doi-asserted-by":"publisher","unstructured":"Riccio BVF, Silvestre ALP, Meneguin AB, Ribeiro T de C, Klosowski AB, Ferrari PC, et al. Exploiting polymeric films as a multipurpose drug delivery system: a Review. AAPS PharmSciTech. 2022;23:1\u201323. https:\/\/doi.org\/10.1208\/s12249-022-02414-6","DOI":"10.1208\/s12249-022-02414-6"},{"key":"2895_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/polym12123015","volume":"12","author":"N Saha","year":"2020","unstructured":"Saha N, Saha N, S\u00e1ha T, \u00d6ner ET, Brodnjak UV, Redl H, et al. Polymer based bioadhesive biomaterials for medical application\u2014a perspective of redefining healthcare system management. Polymers (Basel). 2020;12:1\u201319.","journal-title":"Polymers (Basel)"},{"key":"2895_CR25","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.jddst.2018.05.037","volume":"46","author":"PK Bolla","year":"2018","unstructured":"Bolla PK, Rodriguez VA, Kalhapure RS, Kolli CS, Andrews S, Renukuntla J. A review on pH and temperature responsive gels and other less explored drug delivery systems. J Drug Deliv Sci Technol. 2018;46:416\u201335. https:\/\/doi.org\/10.1016\/j.jddst.2018.05.037.","journal-title":"J Drug Deliv Sci Technol"},{"key":"2895_CR26","doi-asserted-by":"publisher","first-page":"106647","DOI":"10.1016\/j.polymertesting.2020.106647","volume":"90","author":"HM Ibrahim","year":"2020","unstructured":"Ibrahim HM, Klingner A. A review on electrospun polymeric nanofibers: Production parameters and potential applications. Polym Test. 2020;90:106647. https:\/\/doi.org\/10.1016\/j.polymertesting.2020.106647.","journal-title":"Polym Test"},{"key":"2895_CR27","doi-asserted-by":"publisher","first-page":"120248","DOI":"10.1016\/j.memsci.2021.120248","volume":"646","author":"S Huang","year":"2022","unstructured":"Huang S, Mansouri J, Le-Clech P, Leslie G, Tang CY, Fane AG. A comprehensive review of electrospray technique for membrane development: Current status, challenges, and opportunities. J Memb Sci. 2022;646:120248. https:\/\/doi.org\/10.1016\/j.memsci.2021.120248.","journal-title":"J Memb Sci"},{"key":"2895_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ijpharm.2019.118989","volume":"576","author":"R Thakkar","year":"2020","unstructured":"Thakkar R, Thakkar R, Pillai A, Ashour EA, Repka MA. Systematic screening of pharmaceutical polymers for hot melt extrusion processing: a comprehensive review. Int J Pharm. 2020;576:1\u201318. https:\/\/doi.org\/10.1016\/j.ijpharm.2019.118989.","journal-title":"Int J Pharm"},{"key":"2895_CR29","doi-asserted-by":"publisher","first-page":"109582","DOI":"10.1016\/j.foodres.2020.109582","volume":"136","author":"R Suhag","year":"2020","unstructured":"Suhag R, Kumar N, Petkoska AT, Upadhyay A. Film formation and deposition methods of edible coating on food products: A review. Food Res Int. 2020;136:109582. https:\/\/doi.org\/10.1016\/j.foodres.2020.109582.","journal-title":"Food Res Int"},{"key":"2895_CR30","first-page":"207","volume-title":"Aqueous Polym coatings Pharm Dos forms","author":"B Skalsky","year":"2017","unstructured":"Skalsky B, Petereit H-U. Aqueous polymeric coatings for pharmaceutical dosage forms. In: Felton LA, editor. Aqueous Polym coatings Pharm Dos forms. 4th ed. Albuquerque: CRC Press; 2017. p. 207\u201345.","edition":"4"},{"key":"2895_CR31","doi-asserted-by":"publisher","first-page":"30222","DOI":"10.1007\/s11356-020-09315-w","volume":"27","author":"KS Concei\u00e7\u00e3o","year":"2020","unstructured":"Concei\u00e7\u00e3o KS, de Almeida MA, Sawoniuk IC, Marques GD, de Faria-Tischer PCS, Tischer CA, et al. Rhamnolipid production by Pseudomonas aeruginosa grown on membranes of bacterial cellulose supplemented with corn bran water extract. Environ Sci Pollut Res. 2020;27:30222\u201331.","journal-title":"Environ Sci Pollut Res."},{"key":"2895_CR32","unstructured":"Concei\u00e7\u00e3o KS. Ramnolip\u00eddeos: desenvolvimento de biorreator e funcionaliza\u00e7\u00e3o de biocurativo de celulose bacteriana. Universidade Estadual de Londrina; 2022."},{"key":"2895_CR33","volume-title":"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically","author":"CLSI","year":"2012","unstructured":"CLSI. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically. 9th ed. Wayne: Clinical And Laboratory Standards Institute; 2012.","edition":"9"},{"key":"2895_CR34","doi-asserted-by":"publisher","first-page":"2994","DOI":"10.1021\/jm201451h","volume":"55","author":"E Izumi","year":"2012","unstructured":"Izumi E, Ueda-Nakamura T, Veiga VF Jr, Pinto AC, Nakamura CV. Terpenes from copaifera demonstrated in vitro antiparasitic and synergic activity. J Med Chem. 2012;55:2994\u20133001.","journal-title":"J Med Chem"},{"key":"2895_CR35","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.jconrel.2017.09.039","volume":"266","author":"RO do Couto","year":"2017","unstructured":"do Couto RO, Cubayachi C, Calefi PL, Lopez RFV, Pedrazzi V, de Gaitani CM, et al. Combining amino amide salts in mucoadhesive films enhances needle-free buccal anesthesia in adults. J Control Release. 2017;266:205\u201315.","journal-title":"J Control Release."},{"key":"2895_CR36","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1016\/j.injury.2020.02.027","volume":"51","author":"AC Guidi","year":"2020","unstructured":"Guidi AC, de Paula MN, Mosela M, Delanora LA, Soares GCA, de Morais GR, et al. Stem bark extract of Poincianella pluviosa incorporated in polymer film: Evaluation of wound healing and anti-staphylococcal activities. Injury. 2020;51:840\u20139. https:\/\/doi.org\/10.1016\/j.injury.2020.02.027.","journal-title":"Injury"},{"key":"2895_CR37","doi-asserted-by":"publisher","unstructured":"Li X-Q, Ye Z-M, Wang J-B, Fan C-R, Pan A-W, Li C, et al. Mucoadhesive buccal films of tramadol for effective pain management. Brazilian J Anesthesiol (English Ed). 2017;67:231\u20137. \nhttps:\/\/doi.org\/10.1016\/j.bjane.2015.08.016.","DOI":"10.1016\/j.bjane.2015.08.016"},{"key":"2895_CR38","doi-asserted-by":"crossref","unstructured":"de Lucena CAA, da Costa SC, de Eleamen GRA, de Mendon\u00e7a EAM, Oliveira EE. Desenvolvimento de biofilmes \u00e0 base de xilana e xilana\/gelatina para produ\u00e7\u00e3o de embalagens biodegrad\u00e1veis. 2017;27:35\u201341.","DOI":"10.1590\/0104-1428.2223"},{"key":"2895_CR39","unstructured":"ASTM. ASTM E96: Standard Test Methods for Water Vapor Transmission of Materials. 2000."},{"key":"2895_CR40","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1109\/33.19024","volume":"12","author":"RL Opila","year":"1989","unstructured":"Opila RL, Weschler CJ, Schubert R. Acidic vapors above saturated salt solutions commonly used for control of humidity. IEEE Trans Comp Hybrids Manuf Technol. 1989;12:114\u201320.","journal-title":"IEEE Trans Comp Hybrids Manuf Technol"},{"key":"2895_CR41","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1017\/S0007485300028947","volume":"42","author":"ME Solomon","year":"1951","unstructured":"Solomon ME. Control of humidity with potassium hydroxide, sulphuric acid, or other solutions. Bull Entomol Res. 1951;42:543\u201354.","journal-title":"Bull Entomol Res"},{"key":"2895_CR42","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1002\/jps.23944","volume":"103","author":"DJ Lunter","year":"2014","unstructured":"Lunter DJ, Rottke M, Daniels R. Oil-in-oil-emulsions with enhanced substantivity for the treatment of chronic skin diseases. J Pharm Sci. 2014;103:1515\u20139.","journal-title":"J Pharm Sci"},{"key":"2895_CR43","doi-asserted-by":"publisher","first-page":"2074","DOI":"10.1002\/jps.20843","volume":"96","author":"ML Bruschi","year":"2007","unstructured":"Bruschi ML, Jones DS, Panzeri H, Gremi\u00e3o MPD, de Freitas O, Lara EHG. Semisolid systems containing propolis for the treatment of periodontal disease: In vitro release kinetics, syringeability, rheological, textural, and mucoadhesive properties. J Pharm Sci. 2007;96:2074\u201389.","journal-title":"J Pharm Sci."},{"key":"2895_CR44","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/S0939-6411(03)00137-1","volume":"56","author":"T-W Lee","year":"2003","unstructured":"Lee T-W, Kim J-C, Hwang S-J. Hydrogel patches containing Triclosan for acne treatment. Eur J Pharm Biopharm. 2003;56:407\u201312.","journal-title":"Eur J Pharm Biopharm"},{"key":"2895_CR45","first-page":"512","volume":"49","author":"A Brantner","year":"1994","unstructured":"Brantner A, Pfeiffer KP, Brantner H. Applicability of diffusion methods required by the pharmacopoeias for testing antibacterial activity of natural compounds. Pharmazie. 1994;49:512\u20136.","journal-title":"Pharmazie"},{"key":"2895_CR46","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1080\/01621459.1974.10482955","volume":"69","author":"MB Brown","year":"1974","unstructured":"Brown MB, Forsythe AB. Robust tests for the equality of variances. J Am Stat Assoc. 1974;69:364\u20137.","journal-title":"J Am Stat Assoc"},{"key":"2895_CR47","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1080\/00401706.1972.10488921","volume":"14","author":"SS Shapiro","year":"1972","unstructured":"Shapiro SS, Wilk MB. An analysis of variance test for the exponential distribution (Complete Samples). Technometrics. 1972;14:355\u201370.","journal-title":"Technometrics"},{"key":"2895_CR48","first-page":"1","volume":"38","author":"RR Fazli","year":"2018","unstructured":"Fazli RR, Hertadi R. Production and characterization of rhamnolipids from bioconversion of palm oil mill effluent by the halophilic bacterium Pseudomonas stutzeri BK-AB12. Environ Prog Sustain Energy. 2018;38:1\u20136.","journal-title":"Environ Prog Sustain Energy"},{"key":"2895_CR49","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1007\/BF01626559","volume":"10","author":"TR Shryock","year":"1984","unstructured":"Shryock TR, Silver SA, Banschbach MW, Kramer JC. Effect of Pseudomonas aeruginosa rhamnolipid on human neutrophil and monocyte function. Curr Microbiol. 1984;10:323\u20138.","journal-title":"Curr Microbiol"},{"key":"2895_CR50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/antibiotics11050605","volume":"11","author":"Y Abo-Zeid","year":"2022","unstructured":"Abo-Zeid Y, Bakkar MR, Elkhouly GE, Raya NR, Zaafar D. Rhamnolipid nano-micelles versus alcohol-based hand sanitizer: a comparative study for antibacterial activity against hospital-acquired infections and toxicity concerns. Antibiotics. 2022;11:1\u201322.","journal-title":"Antibiotics"},{"key":"2895_CR51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/antibiotics11111556","volume":"11","author":"AM Ali","year":"2022","unstructured":"Ali AM, Hill HJ, Elkhouly GE, Bakkar MR, Raya NR, Stamataki Z, et al. Rhamnolipid nano-micelles inhibit SARS-CoV-2 infection and have no dermal or eye toxic effects in rabbits. Antibiotics. 2022;11:1\u201320.","journal-title":"Antibiotics"},{"key":"2895_CR52","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/1346-8138.14489","volume":"45","author":"E Proksch","year":"2018","unstructured":"Proksch E. pH in nature, humans and skin. J Dermatol. 2018;45:1\u20139.","journal-title":"J Dermatol"},{"key":"2895_CR53","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/j.ijbiomac.2019.02.117","volume":"130","author":"K Ghosal","year":"2019","unstructured":"Ghosal K, Das A, Das SK, Mahmood S, Ramadan MAM, Thomas S. Synthesis and characterization of interpenetrating polymeric networks based bio-composite alginate film: A well-designed drug delivery platform. Int J Biol Macromol. 2019;130:645\u201354. https:\/\/doi.org\/10.1016\/j.ijbiomac.2019.02.117.","journal-title":"Int J Biol Macromol"},{"key":"2895_CR54","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ejps.2020.105558","volume":"155","author":"M Fanous","year":"2020","unstructured":"Fanous M, Gold S, Hirsch S, Ogorka J, Imanidis G. Development of immediate release (IR) 3D-printed oral dosage forms with focus on industrial relevance. Eur J Pharm Sci. 2020;155:1\u201311. https:\/\/doi.org\/10.1016\/j.ejps.2020.105558.","journal-title":"Eur J Pharm Sci"},{"key":"2895_CR55","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.matdes.2020.109075","volume":"196","author":"M Wang","year":"2020","unstructured":"Wang M, Li D, Li J, Li S, Chen Z, Yu DG, et al. Electrospun Janus zein\u2013PVP nanofibers provide a two-stage controlled release of poorly water-soluble drugs. Mater Des. 2020;196:1\u201310. https:\/\/doi.org\/10.1016\/j.matdes.2020.109075.","journal-title":"Mater Des"},{"key":"2895_CR56","doi-asserted-by":"publisher","first-page":"31866","DOI":"10.1016\/j.ceramint.2022.07.120","volume":"48","author":"MKS Souza","year":"2022","unstructured":"Souza MKS, Lima EPN, Nascimento IVSR, Montazerian M, Baino F, Fook MVL. Development, characterization and optimization of a new bone cement based on calcium\u2013strontium aluminates and chitosan-glycerin solution. Ceram Int. 2022;48:31866\u201379. https:\/\/doi.org\/10.1016\/j.ceramint.2022.07.120.","journal-title":"Ceram Int"},{"key":"2895_CR57","first-page":"1","volume":"7","author":"SR Gomari","year":"2018","unstructured":"Gomari SR, Gomari KE, Islam M, Hughes D. New insight into the influence of rhamnolipid bio-surfactant on the carbonate rock\/water\/oil interaction at elevated temperature. Resources. 2018;7:1\u201312.","journal-title":"Resources"},{"key":"2895_CR58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/foods10071584","volume":"10","author":"M S\u00e1nchez-Guti\u00e9rrez","year":"2021","unstructured":"S\u00e1nchez-Guti\u00e9rrez M, Basc\u00f3n-Villegas I, Espinosa E, Carrasco E, P\u00e9rez-Rodr\u00edguez F, Rodr\u00edguez A. Cellulose nanofibers from olive tree pruning as food packaging additive of a biodegradable film. Foods. 2021;10:1\u201315.","journal-title":"Foods"},{"key":"2895_CR59","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1016\/j.jfoodeng.2006.07.016","volume":"80","author":"MA Bertuzzi","year":"2007","unstructured":"Bertuzzi MA, Castro Vidaurre EF, Armada M, Gottifredi JC. Water vapor permeability of edible starch based films. J Food Eng. 2007;80:972\u20138.","journal-title":"J Food Eng"},{"key":"2895_CR60","doi-asserted-by":"publisher","first-page":"1679","DOI":"10.1007\/s10856-014-5204-6","volume":"25","author":"K Ghosal","year":"2014","unstructured":"Ghosal K, Ranjan A, Bhowmik BB. A novel vaginal drug delivery system: Anti-HIV bioadhesive film containing abacavir. J Mater Sci Mater Med. 2014;25:1679\u201389.","journal-title":"J Mater Sci Mater Med"},{"key":"2895_CR61","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.ijpharm.2013.11.033","volume":"461","author":"M Preis","year":"2014","unstructured":"Preis M, Knop K, Breitkreutz J. Mechanical strength test for orodispersible and buccal films. Int J Pharm. 2014;461:22\u20139. https:\/\/doi.org\/10.1016\/j.ijpharm.2013.11.033.","journal-title":"Int J Pharm"},{"key":"2895_CR62","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1063\/1.3160165","volume":"1136","author":"KS Chan","year":"2009","unstructured":"Chan KS, Senin HB, Naimah I. Structural and mechanical properties of polyvinyl alcohol (PVA) thin film. AIP Conf Proc. 2009;1136:366\u20139.","journal-title":"AIP Conf Proc"},{"key":"2895_CR63","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/j.ijpharm.2013.08.077","volume":"457","author":"K Kolter","year":"2013","unstructured":"Kolter K, Dashevsky A, Irfan M, Bodmeier R. Polyvinyl acetate-based film coatings. Int J Pharm. 2013;457:470\u20139. https:\/\/doi.org\/10.1016\/j.ijpharm.2013.08.077.","journal-title":"Int J Pharm"},{"key":"2895_CR64","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1517\/17425247.2011.566266","volume":"8","author":"EA Fouad","year":"2011","unstructured":"Fouad EA, El-Badry M, Neau SH, Alanazi FK, Alsarra IA. Technology evaluation: Kollicoat IR. Expert Opin Drug Deliv. 2011;8:693\u2013703.","journal-title":"Expert Opin Drug Deliv"},{"key":"2895_CR65","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.jallcom.2015.05.262","volume":"646","author":"AM Abdelghany","year":"2015","unstructured":"Abdelghany AM, Mekhail MS, Abdelrazek EM, Aboud MM. Combined DFT\/FTIR structural studies of monodispersed PVP\/Gold and silver nano particles. J Alloys Compd. 2015;646:326\u201332. https:\/\/doi.org\/10.1016\/j.jallcom.2015.05.262.","journal-title":"J Alloys Compd"},{"key":"2895_CR66","volume-title":"Introdu\u00e7\u00e3o \u00e0 espectroscopia","author":"DL Pavia","year":"2010","unstructured":"Pavia DL, Lampman GM, Kriz GS, Vyvyan JR. Introdu\u00e7\u00e3o \u00e0 espectroscopia. 4th ed. Bellingham: Cengage Learning; 2010.","edition":"4"},{"key":"2895_CR67","doi-asserted-by":"publisher","first-page":"33089","DOI":"10.1039\/C5RA01233C","volume":"5","author":"H Hajfarajollah","year":"2015","unstructured":"Hajfarajollah H, Mehvari S, Habibian M, Mokhtarani B, Noghabi KA. Rhamnolipid biosurfactant adsorption on a plasma-treated polypropylene surface to induce antimicrobial and antiadhesive properties. RSC Adv. 2015;5:33089\u201397. https:\/\/doi.org\/10.1039\/C5RA01233C.","journal-title":"RSC Adv"}],"container-title":["AAPS PharmSciTech"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1208\/s12249-024-02895-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1208\/s12249-024-02895-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1208\/s12249-024-02895-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T21:05:54Z","timestamp":1725397554000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1208\/s12249-024-02895-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,31]]},"references-count":67,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["2895"],"URL":"https:\/\/doi.org\/10.1208\/s12249-024-02895-7","relation":{},"ISSN":["1530-9932"],"issn-type":[{"value":"1530-9932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,31]]},"assertion":[{"value":"2 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}],"article-number":"177"}}